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The map label for this gene is cof [C]

Identifier: 237814257

GI number: 237814257

Start: 3882711

End: 3883532

Strand: Reverse

Name: cof [C]

Synonym: GBP346_A4052

Alternate gene names: 237814257

Gene position: 3883532-3882711 (Counterclockwise)

Preceding gene: 237814258

Following gene: 237814253

Centisome position: 94.75

GC content: 64.84

Gene sequence:

>822_bases
ATGTATAAAGCCATCGCTACCGATCTCGACGGAACCCTGCTCAATAGCGACCACCAGCTCGATCCTTATACGATCGACAC
CGTGCGGCGGCTCGCGGGCAGCGGCGTGCCCTTCGTGATCGCGACGGGGCGCCACTATGCGGATGTCGCGGGTATTCGCG
ACGTGCTCGGCATCCGTCCTTACCTGATCACGTCGAACGGCGCGCGCGTGCACGGGCCGGACGACACGCGGATCCACGCG
CAGGACGTGCCCGCCGACGCGGTGCGGCAACTGGTGCGGCCCGAGCTCGTCGGCACGCATGGCCGGGTGATCGTCAATCT
GTTCACGAACGACGGCTGGCTGATCGATCGCGATGCGCCGCAACTGCTCGCATTCCATCAGGATTCCGGATTTCGCTACG
AAATCGTCGATATGCTGGCGCACGACGGCGCGGACATTGCGAAAGTGCTGTACATCGGCGAGCCCGAGGATCTGGCCGTC
GTCTCGGGCAATCTCGCGCGCCGGTTCGGCGACGCGCTGTACGTCACGTATTCGCTGCCCGATTGCCTCGAGGTGATGAC
GGCGAATGTATCGAAGGGGCGCGCGCTGCGCGTCGTGCTCGAGCGGCTCGGCGTCGATCCTGCCCACTGCGTGGCGTTCG
GCGACAACATGAACGATATCGACCTGCTCGAGACGGCCGGGTATCCGTTCATGATGAACAACGCGAATCCCGACCTCGCC
TTGCGCCTGCCGAAGGTGCCGCGGATCGGCAACAACTTCGAAGCGGGCGTCGCGCGCCATCTGCGCGCGCTGTTCGCGCT
CGAGGATTCCATCGCGCACTGA

Upstream 100 bases:

>100_bases
CGGCCCGCCGCGCGGGAATCGACGCCAGTGAGCGGCACGCGTCGTCCGACGATAAAATGTCCGCTCTCTCCCGTGTCAGT
TGCATCCTCCGATGTCCGCC

Downstream 100 bases:

>100_bases
GCGTCGCCGGCCGCTCCGCCGATGGGTGCGGCCCGGCCGCATCCGCCACGAAAACGGGCGCCGCGGCGCCCGTTTTCGCT
TGTGTCCCGCTGCCGTCGGC

Product: HAD hydrolase, IIB family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHGPDDTRIHA
QDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAPQLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEPEDLAV
VSGNLARRFGDALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMNNANPDLA
LRLPKVPRIGNNFEAGVARHLRALFALEDSIAH

Sequences:

>Translated_273_residues
MYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHGPDDTRIHA
QDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAPQLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEPEDLAV
VSGNLARRFGDALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMNNANPDLA
LRLPKVPRIGNNFEAGVARHLRALFALEDSIAH
>Mature_273_residues
MYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHGPDDTRIHA
QDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAPQLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEPEDLAV
VSGNLARRFGDALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMNNANPDLA
LRLPKVPRIGNNFEAGVARHLRALFALEDSIAH

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI48994981, Length=266, Percent_Identity=38.3458646616541, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI87081741, Length=261, Percent_Identity=37.1647509578544, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI2367265, Length=284, Percent_Identity=29.9295774647887, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 29889; Mature: 29889

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDVLGIRP
CCCCEECCCCCEEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCC
YLITSNGARVHGPDDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAP
EEEECCCCEEECCCCCEEEECCCCHHHHHHHHCHHHCCCCCEEEEEEECCCCEEEECCCC
QLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEPEDLAVVSGNLARRFGDALYVTYSLP
CEEEEECCCCCEEHHHHHHHCCCCCEEEEEEECCCCCEEEECCHHHHHCCCEEEEEECCH
DCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMNNANPDLA
HHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHCCCCEEECCCCCCEE
LRLPKVPRIGNNFEAGVARHLRALFALEDSIAH
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDVLGIRP
CCCCEECCCCCEEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCC
YLITSNGARVHGPDDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAP
EEEECCCCEEECCCCCEEEECCCCHHHHHHHHCHHHCCCCCEEEEEEECCCCEEEECCCC
QLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEPEDLAVVSGNLARRFGDALYVTYSLP
CEEEEECCCCCEEHHHHHHHCCCCCEEEEEEECCCCCEEEECCHHHHHCCCEEEEEECCH
DCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMNNANPDLA
HHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHCCCCEEECCCCCCEE
LRLPKVPRIGNNFEAGVARHLRALFALEDSIAH
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]