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The map label for this gene is lrp [H]

Identifier: 237814176

GI number: 237814176

Start: 3809265

End: 3809843

Strand: Reverse

Name: lrp [H]

Synonym: GBP346_A3970

Alternate gene names: 237814176

Gene position: 3809843-3809265 (Counterclockwise)

Preceding gene: 237814178

Following gene: 237814167

Centisome position: 92.96

GC content: 64.59

Gene sequence:

>579_bases
TTGGTCGCGCAACGCTACGCTTGCGCAATTTCTCGTCCGCACGAACAGGCAGGGAGACAGGAAATGGCGCACGTGGAATT
GGATGCGATTGACCGGCGCATTCTTTCTATCCTTCAGGAGAATGGGCGTTTGTCGAACCAGGACATCGCCGAGCGGGTGA
ATCTGTCGCCGAGTCCTTGCCTGAGGCGGATCCGCCGGCTCGAGGAAATGGGCGTGATCACCGGCTACGTCGCGCTGCTC
GATCCGCAGAAGCTCGGGCTCGATCTGCTCGCGTACGTGAGCGTGCGGCTGGAGAAGCGCGGCGGCGTCGCGCCCGTGCG
CGGCGACGAGACGTCCGCGCGCGCCGGCGCGACCCATGCCGAGCTGTTCCGCGCGGCGGTGCAGGCGTGGCCGGAAGTGG
TCGCGTGCCACGCGATGACGGGCGACATGGATTATCTGCTGCGCGTGCAGGTCGAGGACATGGCGCATTTCTCGCGCTTC
ATGCAGGAGCAACTGCTGCACCATCCGTCGGTGATCGACGTGAAGACGAGTTTCTCGCTCGAGCGCTTCAAGGAAACGAC
CGCGCTGCCGATCCGCTGA

Upstream 100 bases:

>100_bases
GGGGATTTGCATGGCGTCTCCTAGCCCTCGGCGGGGCACGCGTCTTGGTGAATGTCTGCGGCAAAGTGTAGCGGGGAGGG
CCGAGTGGAAACTTGCGAAC

Downstream 100 bases:

>100_bases
ACAGCATACATACGGATGCGCGGCCGGCCGGGCGGCCGCACGGCGTGCGCCGCGGCCGGCTCAAAAAAACGGGCGGCCCG
TTGTGGACCGCCCGTTCCCG

Product: transcriptional regulator, AsnC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MVAQRYACAISRPHEQAGRQEMAHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPCLRRIRRLEEMGVITGYVALL
DPQKLGLDLLAYVSVRLEKRGGVAPVRGDETSARAGATHAELFRAAVQAWPEVVACHAMTGDMDYLLRVQVEDMAHFSRF
MQEQLLHHPSVIDVKTSFSLERFKETTALPIR

Sequences:

>Translated_192_residues
MVAQRYACAISRPHEQAGRQEMAHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPCLRRIRRLEEMGVITGYVALL
DPQKLGLDLLAYVSVRLEKRGGVAPVRGDETSARAGATHAELFRAAVQAWPEVVACHAMTGDMDYLLRVQVEDMAHFSRF
MQEQLLHHPSVIDVKTSFSLERFKETTALPIR
>Mature_192_residues
MVAQRYACAISRPHEQAGRQEMAHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPCLRRIRRLEEMGVITGYVALL
DPQKLGLDLLAYVSVRLEKRGGVAPVRGDETSARAGATHAELFRAAVQAWPEVVACHAMTGDMDYLLRVQVEDMAHFSRF
MQEQLLHHPSVIDVKTSFSLERFKETTALPIR

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=167, Percent_Identity=40.7185628742515, Blast_Score=130, Evalue=4e-32,
Organism=Escherichia coli, GI87081742, Length=165, Percent_Identity=40, Blast_Score=127, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 21615; Mature: 21615

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAQRYACAISRPHEQAGRQEMAHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPC
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHH
LRRIRRLEEMGVITGYVALLDPQKLGLDLLAYVSVRLEKRGGVAPVRGDETSARAGATHA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
ELFRAAVQAWPEVVACHAMTGDMDYLLRVQVEDMAHFSRFMQEQLLHHPSVIDVKTSFSL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
ERFKETTALPIR
HHHHHCCCCCCC
>Mature Secondary Structure
MVAQRYACAISRPHEQAGRQEMAHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPC
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHH
LRRIRRLEEMGVITGYVALLDPQKLGLDLLAYVSVRLEKRGGVAPVRGDETSARAGATHA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
ELFRAAVQAWPEVVACHAMTGDMDYLLRVQVEDMAHFSRFMQEQLLHHPSVIDVKTSFSL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
ERFKETTALPIR
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]