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The map label for this gene is recQ [H]

Identifier: 237814152

GI number: 237814152

Start: 3776918

End: 3778765

Strand: Reverse

Name: recQ [H]

Synonym: GBP346_A3938

Alternate gene names: 237814152

Gene position: 3778765-3776918 (Counterclockwise)

Preceding gene: 237814155

Following gene: 237814150

Centisome position: 92.2

GC content: 68.07

Gene sequence:

>1848_bases
ATGTCCCGTTCGCTCGAAATTCTCAACGAAGTCTTCGGCTATCCCGCCTTCCGAGGTCAACAGGGCGAGATCGTCGAGCA
CGTTGCGGCGGGCGGCGACTGTCTCGTGCTGATGCCCACGGGCGGCGGCAAGTCGCTCTGCTACCAGATTCCGGCGCTCG
TGCGCAGCGAAGCGGGCCGCGGCGCGGGCATCGTCGTGTCGCCGCTCATCGCGCTGATGCAGGATCAGGTCGCCGCATTG
TCCGAGGTCGGCGTGCGCGCCGCGTATCTGAACTCGACGCTGTCGGGGGCCGAGGCGGCCGCGACCGAACGCGCGCTGCG
CGACGGCGACATCGATCTGCTCTACGTCGCGCCCGAGCGGCTGATGACGCCGCGCTTCCTCGATCTGCTCGAGCGCGCGC
GCATCGGGCTTTTCGCGATCGACGAGGCGCACTGCGTATCGCAGTGGGGGCACGATTTCCGGCCCGAGTACATTCAGCTG
TCGGTGCTGCACGAGCGCTTTCCGGACGTGCCGCGGATCGCGCTGACCGCGACCGCCGATGCGATCACCCGCGACGAGAT
CGTGCAGCGTCTGGCGCTCGACGACGCGCGAATCTTCGTGTCGAGCTTCGACCGGCCGAACATCCGCTACCGGATCGTCG
AAAAGGACAACGCGCGCTCGCAGTTGCTCGACTTCATTCGCGCCGAGCATACGAACGCCGACGGTACGACCGACGCTGGC
GTCGTGTACTGCCTGTCGCGCCGCAAGGTCGAGGAGACGGCCGAATGGCTGAAGGCGCAAGGGGTTCGTGCGCTGCCGTA
TCACGCGGGAATGGAGTTCGAGATCCGGCAGAAGCACCAGGAGATGTTCCAGCGCGAGGAAGGGGTCGTGATGTGCGCGA
CGATCGCGTTCGGCATGGGCATCGACAAGCCGGACGTGCGCTTCGTCGCACACCTGGATCTGCCGAAGAGCGTCGAAGGC
TATTACCAGGAGACCGGACGCGCGGGGCGCGACGGCCTGCCGGCGAACGCGTGGATGGCGTACGGGCTCGGCGACGTCGT
TCAGCAGCGCAAGATGATCGACGAATCGGAAGCCGACGACACGCACAAGCGTGTCCAGACGTCGAAGCTCGACGCGCTGC
TCGGGCTGTGCGAGACGGCATCGTGCCGCCGCGTGCGGCTCCTCGCGTATTTCGGCGAGACGAGCGGCCCGTGCGGCAAC
TGCGACACCTGCCTCGAGCCGCCGGCGACATGGGACGCGACGCGCGAAGCGCAGATGGCGCTGTCGTGCGTATTCCGCGC
GCAGCGCGCAAGCGGCTTCAATTTCGGCGCGAGCCATCTGATCGAAGTGCTGCGCGGTGCGCGGACCGAGAAGGTCCAGC
AACGCGGCCACGACAGTCTCAGCACGTTCGGCATCGGCGCCGAGTTGTCCGAAGCCGAATGGCGCGCGATCTTCCGGCAG
CTCGTCGCGTTCGGCTATCTCGCCGTCGACCACGGCGGCTTCGGCGCGCTCGTGCTGACGGAGGCGAGCAAGCCGGTGCT
CAAGGGCGAGGAGAAGGTCACGCTGCGCCGCTACGTGAAGCCGGCGCGCACACGGCAGTCCTCCGGCCGCAGCGGCGCGC
GCGTCGATCCGACGGCCGGCATGAGCGCGCGCGAGCGCGCGTGCTGGGAGCGCCTGCGCGCGTGGCGCGCGGAAACGGCG
AAGAGCGACGGCGTGCCTGCGTACGTGATCTTCCACGACGCGACGCTCGCGGAGATCGCGCGCAACGCGCCCGAATCGAT
CGACGATCTGCGCCATATCCCCGGAATCGGCGCGCGCAAGCTCGATCGCTTCGGCGACGAGATTCTCGAGGTCGTCGAGT
CGGCCTGA

Upstream 100 bases:

>100_bases
CCGAATGGACGACGTGCGACCTTCGTCCACCTTTCGCGGCGGCGACGTTGGTAAAATTCACGCCACCGCCCCTTTTCGCA
GCCCATCCATCTCCAGATCC

Downstream 100 bases:

>100_bases
GCAGGCCGCCCGCCTTTGCATTCCGGCACCAAAAATCACGCAAGCTGTTGACTCGCTTGGGATTTTCGGAATATCATGCC
GGGTTCCGGTTCTCGGTGGG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MSRSLEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIPALVRSEAGRGAGIVVSPLIALMQDQVAAL
SEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLERARIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGVVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESEADDTHKRVQTSKLDALLGLCETASCRRVRLLAYFGETSGPCGN
CDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGARTEKVQQRGHDSLSTFGIGAELSEAEWRAIFRQ
LVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRSGARVDPTAGMSARERACWERLRAWRAETA
KSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEVVESA

Sequences:

>Translated_615_residues
MSRSLEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIPALVRSEAGRGAGIVVSPLIALMQDQVAAL
SEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLERARIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGVVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESEADDTHKRVQTSKLDALLGLCETASCRRVRLLAYFGETSGPCGN
CDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGARTEKVQQRGHDSLSTFGIGAELSEAEWRAIFRQ
LVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRSGARVDPTAGMSARERACWERLRAWRAETA
KSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEVVESA
>Mature_614_residues
SRSLEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIPALVRSEAGRGAGIVVSPLIALMQDQVAALS
EVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLERARIGLFAIDEAHCVSQWGHDFRPEYIQLS
VLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAGV
VYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGVVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGY
YQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESEADDTHKRVQTSKLDALLGLCETASCRRVRLLAYFGETSGPCGNC
DTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGARTEKVQQRGHDSLSTFGIGAELSEAEWRAIFRQL
VAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRSGARVDPTAGMSARERACWERLRAWRAETAK
SDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEVVESA

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=650, Percent_Identity=34.4615384615385, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI14591902, Length=417, Percent_Identity=37.8896882494005, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI14591904, Length=417, Percent_Identity=37.8896882494005, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI148612816, Length=431, Percent_Identity=39.4431554524362, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI169218196, Length=606, Percent_Identity=32.1782178217822, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI110735439, Length=606, Percent_Identity=32.1782178217822, Blast_Score=259, Evalue=8e-69,
Organism=Homo sapiens, GI51242947, Length=394, Percent_Identity=40.1015228426396, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI51242943, Length=394, Percent_Identity=40.1015228426396, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI284005309, Length=347, Percent_Identity=36.5994236311239, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI148613856, Length=347, Percent_Identity=25.6484149855908, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI38201710, Length=347, Percent_Identity=25.6484149855908, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI4758138, Length=346, Percent_Identity=25.1445086705202, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI48994977, Length=614, Percent_Identity=44.7882736156352, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI87082221, Length=346, Percent_Identity=24.8554913294798, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=663, Percent_Identity=35.4449472096531, Blast_Score=339, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI71987993, Length=410, Percent_Identity=40, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI71987997, Length=410, Percent_Identity=40, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI32564293, Length=672, Percent_Identity=30.3571428571429, Blast_Score=281, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17552866, Length=448, Percent_Identity=36.6071428571429, Blast_Score=255, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI17510307, Length=325, Percent_Identity=25.5384615384615, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17510309, Length=325, Percent_Identity=25.5384615384615, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995718, Length=336, Percent_Identity=23.5119047619048, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995514, Length=325, Percent_Identity=25.5384615384615, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71987143, Length=331, Percent_Identity=25.6797583081571, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115533224, Length=350, Percent_Identity=24, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=542, Percent_Identity=35.4243542435424, Blast_Score=349, Evalue=6e-97,
Organism=Saccharomyces cerevisiae, GI6324778, Length=232, Percent_Identity=27.1551724137931, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325138, Length=335, Percent_Identity=25.0746268656716, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646066, Length=642, Percent_Identity=36.4485981308411, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24664226, Length=456, Percent_Identity=37.0614035087719, Blast_Score=269, Evalue=4e-72,
Organism=Drosophila melanogaster, GI62472181, Length=437, Percent_Identity=37.7574370709382, Blast_Score=265, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24664230, Length=437, Percent_Identity=37.7574370709382, Blast_Score=265, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21358123, Length=361, Percent_Identity=34.9030470914127, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI28574962, Length=354, Percent_Identity=24.8587570621469, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67829; Mature: 67698

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSLEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIPALVRSEAGR
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
GAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECHHH
LMTPRFLDLLERARIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATAD
HCCHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCEEEEECHH
AITRDEIVQRLALDDARIFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGVVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESEADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHHCCCCCCH
THKRVQTSKLDALLGLCETASCRRVRLLAYFGETSGPCGNCDTCLEPPATWDATREAQMA
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LSCVFRAQRASGFNFGASHLIEVLRGARTEKVQQRGHDSLSTFGIGAELSEAEWRAIFRQ
HHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHH
LVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRSGARVDPTAG
HHHHHHHEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCCC
MSARERACWERLRAWRAETAKSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARK
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHCCCCCHHH
LDRFGDEILEVVESA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRSLEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIPALVRSEAGR
CCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
GAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECHHH
LMTPRFLDLLERARIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATAD
HCCHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCEEEEECHH
AITRDEIVQRLALDDARIFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGVVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESEADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHHCCCCCCH
THKRVQTSKLDALLGLCETASCRRVRLLAYFGETSGPCGNCDTCLEPPATWDATREAQMA
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LSCVFRAQRASGFNFGASHLIEVLRGARTEKVQQRGHDSLSTFGIGAELSEAEWRAIFRQ
HHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHH
LVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRSGARVDPTAG
HHHHHHHEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCCC
MSARERACWERLRAWRAETAKSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARK
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHCCCCCHHH
LDRFGDEILEVVESA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]