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The map label for this gene is visC [H]

Identifier: 237813955

GI number: 237813955

Start: 3611236

End: 3612417

Strand: Reverse

Name: visC [H]

Synonym: GBP346_A3739

Alternate gene names: 237813955

Gene position: 3612417-3611236 (Counterclockwise)

Preceding gene: 237813956

Following gene: 237813954

Centisome position: 88.14

GC content: 71.91

Gene sequence:

>1182_bases
ATGCCCGCCATGACTGCCTATCATCAGACCTTCGACGTCGCCGTCGTCGGCGGCGGCCTCGTCGGCAAGACGGCCGCGCT
CGCGCTGACGCAGGCGGGCCACAAGACCGCGCTGCTCGCGCAGCCAGCCGTCCCGCGCCCCGCCGATCTCGCGTTCGACT
CGCGCATCTACGCGCTATCCGCGAGCTCGCAGGCGCTGCTCGAGCGGCTGCGCGTGTGGCAAGCGCTCGACCACGGCCGG
CTCGCGCCCGTCTACGACATGCGCGTCTATGGCGACGCGCACGCCGAGCTGCACTTCTCCGCGTTCCAGTCGGCGGTGTC
GCAGCTCGCGTGGATCGGCGAATCGTCGCTGATCGAATGCGCGCTCGATGCCGCGCTGCGCTTCCAGCCGAACCTCACGT
GGTTCGACGCGCGCGCGCAAGGCCTCGACGTGACCCCGGGCGCCGCGACGCTCGCGCTCGCGAACGGCGACGTGATCGAA
TGCGATCTCGTCGTCGGCGCGGACGGCGCGCATTCGTGGGTGCGCTCGCAGATCGGCTCGAAGGTCGAGCGGCGCGATTA
CCGGCAGACGGGCGTCGTCGCGAATTTCAAGGCGGCGCAGCCGCATCGCGAGACCGCCTATCAATGGTTCCGCGACGGCG
AGATCGTCGCGCTGCTGCCGCTGCCGGACGGCCACGTGTCGCTCGTGTGGTCGGCGCACACCGCGCACGCCGACGAGCTG
CTCGCGCTCGATCCCGCGCGGCTCGCGGCTGAAGTCGAGCGCGTGACGCTGAACCGCCTCGGCGCGCTCGAGTGCATGAC
GCCCGCGCAGGGTTTCCCGCTCGCGCTGCAGACGGTCGACCGGCTGGTCGCGCCGCGCGTCGCCCTCGTCGGCGACGCCG
CGCACCTGATTCACCCGCTCGCGGGCCAGGGGATGAACCTTGGGCTGCGCGATGTCGCCGCGCTCGCCGATGTCCTCGCG
AACCGCGAAGCGTTCCGCGATCTCGGCGACACCGTGCTGCTGCGCCGCTACGAGCGCGCGCGGCGCGAGGACATTCGTGC
GCTGATGGTCGCGACCGACGGCTTGCAGCGGCTTTTCTCGCTGCCGGGCGCGCTTGCGCGCATCGTGCGCAACGCGGGAA
TGGCGCTCGTCGGTGCGCAGCCGCTCGTCAAGCGCTGGCTGGTCGCCTCGGCGCTCGGCTGA

Upstream 100 bases:

>100_bases
CGCGGCCGCCGCGAAACCGGCACGGCGCGTGCGGCGCCGTGCCGCGCACCCTGATTTACCGCAAGCTCCCCCGCGAAGCG
GCACGGCCCTCCCGGCTATA

Downstream 100 bases:

>100_bases
CGCGCGGCGCGAACCTTCGCGCGGCGCGGCGGTCGGACACTGCTCGGCCACAGTCAGTCGTACACTGTGGCGATGCACGC
ACGCTTTGAAGGATGATTTG

Product: ubiquinone biosynthesis hydroxylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPAMTAYHQTFDVAVVGGGLVGKTAALALTQAGHKTALLAQPAVPRPADLAFDSRIYALSASSQALLERLRVWQALDHGR
LAPVYDMRVYGDAHAELHFSAFQSAVSQLAWIGESSLIECALDAALRFQPNLTWFDARAQGLDVTPGAATLALANGDVIE
CDLVVGADGAHSWVRSQIGSKVERRDYRQTGVVANFKAAQPHRETAYQWFRDGEIVALLPLPDGHVSLVWSAHTAHADEL
LALDPARLAAEVERVTLNRLGALECMTPAQGFPLALQTVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLA
NREAFRDLGDTVLLRRYERARREDIRALMVATDGLQRLFSLPGALARIVRNAGMALVGAQPLVKRWLVASALG

Sequences:

>Translated_393_residues
MPAMTAYHQTFDVAVVGGGLVGKTAALALTQAGHKTALLAQPAVPRPADLAFDSRIYALSASSQALLERLRVWQALDHGR
LAPVYDMRVYGDAHAELHFSAFQSAVSQLAWIGESSLIECALDAALRFQPNLTWFDARAQGLDVTPGAATLALANGDVIE
CDLVVGADGAHSWVRSQIGSKVERRDYRQTGVVANFKAAQPHRETAYQWFRDGEIVALLPLPDGHVSLVWSAHTAHADEL
LALDPARLAAEVERVTLNRLGALECMTPAQGFPLALQTVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLA
NREAFRDLGDTVLLRRYERARREDIRALMVATDGLQRLFSLPGALARIVRNAGMALVGAQPLVKRWLVASALG
>Mature_392_residues
PAMTAYHQTFDVAVVGGGLVGKTAALALTQAGHKTALLAQPAVPRPADLAFDSRIYALSASSQALLERLRVWQALDHGRL
APVYDMRVYGDAHAELHFSAFQSAVSQLAWIGESSLIECALDAALRFQPNLTWFDARAQGLDVTPGAATLALANGDVIEC
DLVVGADGAHSWVRSQIGSKVERRDYRQTGVVANFKAAQPHRETAYQWFRDGEIVALLPLPDGHVSLVWSAHTAHADELL
ALDPARLAAEVERVTLNRLGALECMTPAQGFPLALQTVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAN
REAFRDLGDTVLLRRYERARREDIRALMVATDGLQRLFSLPGALARIVRNAGMALVGAQPLVKRWLVASALG

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=386, Percent_Identity=29.2746113989637, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI32967307, Length=277, Percent_Identity=32.8519855595668, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1789273, Length=390, Percent_Identity=34.1025641025641, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1786883, Length=393, Percent_Identity=35.1145038167939, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1789274, Length=372, Percent_Identity=32.258064516129, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25146631, Length=417, Percent_Identity=30.9352517985612, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6321694, Length=464, Percent_Identity=25.6465517241379, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920760, Length=439, Percent_Identity=31.6628701594533, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42277; Mature: 42146

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAMTAYHQTFDVAVVGGGLVGKTAALALTQAGHKTALLAQPAVPRPADLAFDSRIYALS
CCCCCHHHHEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEC
ASSQALLERLRVWQALDHGRLAPVYDMRVYGDAHAELHFSAFQSAVSQLAWIGESSLIEC
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
ALDAALRFQPNLTWFDARAQGLDVTPGAATLALANGDVIECDLVVGADGAHSWVRSQIGS
HHHHHHEECCCCEEEECCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCHHHHHHHHHCC
KVERRDYRQTGVVANFKAAQPHRETAYQWFRDGEIVALLPLPDGHVSLVWSAHTAHADEL
HHHHHHHHHHCCEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHH
LALDPARLAAEVERVTLNRLGALECMTPAQGFPLALQTVDRLVAPRVALVGDAAHLIHPL
EECCHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCHHHEECCHHHHHHHH
AGQGMNLGLRDVAALADVLANREAFRDLGDTVLLRRYERARREDIRALMVATDGLQRLFS
CCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPGALARIVRNAGMALVGAQPLVKRWLVASALG
CCHHHHHHHHHCCEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAMTAYHQTFDVAVVGGGLVGKTAALALTQAGHKTALLAQPAVPRPADLAFDSRIYALS
CCCCHHHHEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEC
ASSQALLERLRVWQALDHGRLAPVYDMRVYGDAHAELHFSAFQSAVSQLAWIGESSLIEC
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
ALDAALRFQPNLTWFDARAQGLDVTPGAATLALANGDVIECDLVVGADGAHSWVRSQIGS
HHHHHHEECCCCEEEECCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCHHHHHHHHHCC
KVERRDYRQTGVVANFKAAQPHRETAYQWFRDGEIVALLPLPDGHVSLVWSAHTAHADEL
HHHHHHHHHHCCEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHH
LALDPARLAAEVERVTLNRLGALECMTPAQGFPLALQTVDRLVAPRVALVGDAAHLIHPL
EECCHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCHHHEECCHHHHHHHH
AGQGMNLGLRDVAALADVLANREAFRDLGDTVLLRRYERARREDIRALMVATDGLQRLFS
CCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPGALARIVRNAGMALVGAQPLVKRWLVASALG
CCHHHHHHHHHCCEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]