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The map label for this gene is gph_2 [C]

Identifier: 237813945

GI number: 237813945

Start: 3600965

End: 3601702

Strand: Direct

Name: gph_2 [C]

Synonym: GBP346_A3729

Alternate gene names: 237813945

Gene position: 3600965-3601702 (Clockwise)

Preceding gene: 237813944

Following gene: 237813946

Centisome position: 87.86

GC content: 66.94

Gene sequence:

>738_bases
GTGAGCACGATGACGACGTCGCCTCTCAATGGCGCGCCGCGCATCGAAGCGGCGCTCATCGATCTCGACGGCACGATGGT
CGATACCGCAGACGATTTCACGGCCGGCCTGAACGCGATGCTCGCGCAGCTCGATGCCGAGGAGACGACGCGCGAGGAAG
TGATGCGCTATGTCGGCAAGGGTTCGGAGAACCTGATCCAGTGCGTGCTGACGCCGCGCTTTTCCGCAGACGACGCGAAC
GCGCGCTTCGACGAGGCGCTCGCGCTCTATCAGGCCGAATACGCGAAGATCAACGGCCGCCACACGCGGCTCTACCCGGA
CGTCGACGCAGGCTTGCGGGCGATGCGTGAAGCGGGCGTCAAGCTCGCATGCGTGACGAACAAGCCGTGCCGGTTCGCGG
TCGAGCTGCTCGCGCAGTACAGCCTGTCCGGCCATTTCTCCGCGGTGTTCGGCGGCGACAGCGTGCCGCGCAAGAAGCCC
GATCCGGCGCCGATGCTCGCCGCATGCGCCGCGCTCGGCGTCGCGCCGCGCGCGGCGGTCGCGATCGGCGATTCGGAGAA
CGACGCGCTCGCGGGCCGCGCGGCCGGGATGGCGACGCTGACGGTGCCGTACGGCTACAACCACGGCAACGCTATACAAA
CGATCGAATCGGATGGTATAGTCGATTCGCTTCTCGCCGCCGCACGGCTCATCGCCGCGCACAATTCGGCAGGATCAGCG
GCAAGATCAGCCATCTGA

Upstream 100 bases:

>100_bases
GCGCCGATACGTTCGTCGCGGGCTCGGCGATCTTCGGCAAGCCCGACTATCGGCAGGTGATCGGCGAGATGCGCGACGCG
CTCGCCACCGTCGGGCGCGC

Downstream 100 bases:

>100_bases
CTTTTTCTTCCATCCGCATGTTTCTGAACAAAAAACGGAGTCTGAGCAGCATCGACCGGGGAGCCTGGCCCTGGCGTCGC
TGGTCGCGCCAACCTCGATG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSTMTTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGKGSENLIQCVLTPRFSADDAN
ARFDEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGVKLACVTNKPCRFAVELLAQYSLSGHFSAVFGGDSVPRKKP
DPAPMLAACAALGVAPRAAVAIGDSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSA
ARSAI

Sequences:

>Translated_245_residues
MSTMTTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGKGSENLIQCVLTPRFSADDAN
ARFDEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGVKLACVTNKPCRFAVELLAQYSLSGHFSAVFGGDSVPRKKP
DPAPMLAACAALGVAPRAAVAIGDSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSA
ARSAI
>Mature_244_residues
STMTTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGKGSENLIQCVLTPRFSADDANA
RFDEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGVKLACVTNKPCRFAVELLAQYSLSGHFSAVFGGDSVPRKKPD
PAPMLAACAALGVAPRAAVAIGDSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSAA
RSAI

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=247, Percent_Identity=32.3886639676113, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25632; Mature: 25501

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMTTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGK
CCCCCCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
GSENLIQCVLTPRFSADDANARFDEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGV
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCC
KLACVTNKPCRFAVELLAQYSLSGHFSAVFGGDSVPRKKPDPAPMLAACAALGVAPRAAV
EEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEE
AIGDSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSA
EECCCCCCCHHHHCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCH
ARSAI
HHCCC
>Mature Secondary Structure 
STMTTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGK
CCCCCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
GSENLIQCVLTPRFSADDANARFDEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGV
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCC
KLACVTNKPCRFAVELLAQYSLSGHFSAVFGGDSVPRKKPDPAPMLAACAALGVAPRAAV
EEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEE
AIGDSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSA
EECCCCCCCHHHHCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCH
ARSAI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA