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The map label for this gene is paaD [H]

Identifier: 237813940

GI number: 237813940

Start: 3596335

End: 3596727

Strand: Direct

Name: paaD [H]

Synonym: GBP346_A3723

Alternate gene names: 237813940

Gene position: 3596335-3596727 (Clockwise)

Preceding gene: 237813939

Following gene: 237813941

Centisome position: 87.75

GC content: 64.38

Gene sequence:

>393_bases
ATGTACGCCGCGGACGCCTGCAGCCGCAGCCTCGGCATCGAGGTGCTCGAAGTGCGGCCGGGCTACGCGCGCGCGCGCAT
GCCCGTGCGCGGCGATTTTCTGAACGGTCACCAGATCTGCCATGGTGGGCTCGTCTTCACGCTCGCGGATTCGACCTTCG
CGTTCGCCTGCAACTCGTACAACATCAATACGGTCGCAGCCGGCTGCTCGATCGAATTCCTGCGCCCGGTGGCGGGCGGC
GACGTGCTCACCGCGGAAGCGACGGAGCAGACGCTGAACGGCCGGCACGGCATCTACGATATTCGCGTAACGAATCGGGC
GGGAGAAACCGTCGCGATGTTCCGCGGCAAGTCGACTCAAATCAAAGGGACGGTGATCCCTGTAGACCGTTAG

Upstream 100 bases:

>100_bases
TTCGAAGGACGCTGAGATGGCCGCACGCTCTCCCGAACGCTCGCCAACGGCGACCGCAGAACGCTCCGCCGAAGCGCTCG
CCCGCGCAACCGCCGAAGCA

Downstream 100 bases:

>100_bases
CGTCCACGCACGCTCACATAAATATATTGGAGACATCATGGCAACCTCGCTTCCGCTCGACCCGATCGAACGAGCGAGCC
GCGACGAACTGCTCGCGCTT

Product: phenylacetic acid degradation protein PaaD

Products: NA

Alternate protein names: Phenylacetic acid degradation protein PaaI [H]

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MYAADACSRSLGIEVLEVRPGYARARMPVRGDFLNGHQICHGGLVFTLADSTFAFACNSYNINTVAAGCSIEFLRPVAGG
DVLTAEATEQTLNGRHGIYDIRVTNRAGETVAMFRGKSTQIKGTVIPVDR

Sequences:

>Translated_130_residues
MYAADACSRSLGIEVLEVRPGYARARMPVRGDFLNGHQICHGGLVFTLADSTFAFACNSYNINTVAAGCSIEFLRPVAGG
DVLTAEATEQTLNGRHGIYDIRVTNRAGETVAMFRGKSTQIKGTVIPVDR
>Mature_130_residues
MYAADACSRSLGIEVLEVRPGYARARMPVRGDFLNGHQICHGGLVFTLADSTFAFACNSYNINTVAAGCSIEFLRPVAGG
DVLTAEATEQTLNGRHGIYDIRVTNRAGETVAMFRGKSTQIKGTVIPVDR

Specific function: Thioesterase with a preference for ring-hydroxylated phenylacetyl-CoA esters. Hydrolyzes 3,4-dihydroxyphenylacetyl-CoA, 3-hydroxyphenylacetyl-CoA and 4-hydroxyphenylacetyl-CoA. Inactive towards 4-hydroxybenzoyl-CoA and 4-hydroxyphenacyl-CoA [H]

COG id: COG2050

COG function: function code Q; Uncharacterized protein, possibly involved in aromatic compounds catabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase PaaI family [H]

Homologues:

Organism=Escherichia coli, GI1787662, Length=125, Percent_Identity=48.8, Blast_Score=134, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011973
- InterPro:   IPR003736
- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: NA

Molecular weight: Translated: 13968; Mature: 13968

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAADACSRSLGIEVLEVRPGYARARMPVRGDFLNGHQICHGGLVFTLADSTFAFACNSY
CCCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCEEECCCEEEEEECCEEEEEECCC
NINTVAAGCSIEFLRPVAGGDVLTAEATEQTLNGRHGIYDIRVTNRAGETVAMFRGKSTQ
CCEEEEECCEEEEECCCCCCCEEEECCCHHHCCCCCCEEEEEEECCCCCEEEEEECCCCE
IKGTVIPVDR
EEEEEEECCC
>Mature Secondary Structure
MYAADACSRSLGIEVLEVRPGYARARMPVRGDFLNGHQICHGGLVFTLADSTFAFACNSY
CCCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCEEECCCEEEEEECCEEEEEECCC
NINTVAAGCSIEFLRPVAGGDVLTAEATEQTLNGRHGIYDIRVTNRAGETVAMFRGKSTQ
CCEEEEECCEEEEECCCCCCCEEEECCCHHHCCCCCCEEEEEEECCCCCEEEEEECCCCE
IKGTVIPVDR
EEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]