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The map label for this gene is aroE [H]

Identifier: 237813862

GI number: 237813862

Start: 3512778

End: 3513656

Strand: Reverse

Name: aroE [H]

Synonym: GBP346_A3640

Alternate gene names: 237813862

Gene position: 3513656-3512778 (Counterclockwise)

Preceding gene: 237813863

Following gene: 237813861

Centisome position: 85.73

GC content: 73.04

Gene sequence:

>879_bases
ATGAGCACGGCCGTCGAATCGGCAGCGCGCGCGCGCGATCGCTATGCGGTGATCGGCAATCCGATCGCGCACAGCAAATC
GCCGTTCATCCATTCGCGTTTCGCCGAGCAGACGGGCGAGGCGATCGAATACACGCATCTGCTCGCGCCGCTCGACGGCT
TTTCGGCCACGGTGCGCGCGTTCATCGCGCAGGGCGGCCGCGGCGTGAACGTCACGGTGCCGTTCAAGCTCGAGGCCTAT
GCGCTCGCCGATGCGCTGTCGCCGCGCGCGGCGGCGGCGGGCGCGGTCAACACGCTGCGCTTCGACGCGGACGGCGTTTT
CGGCGACAACACCGACGGCGTCGGCCTCGTGCGCGACATCGAGGTGAATCTCGGCGTGAGCCTCACGGGCGCGCGGATCC
TGCTGCTCGGCGCGGGCGGCGCGGCACGCGGCGTCGTGCTGCCGATGCTCGAGCGCGGGCCCGCGTCGCTCACGATCGTC
AACCGGACCGCGAGCAAGGCGGAAGAACTCGTCGGCCAGTTCACGCAGGCGGCGCACGACGCGGGCTGCGTGCTCGCCGG
CGGCGGGCCCGAACGGATCGCGCGCGAGCCGTACGACGTGATCGTCAACGCGACGGCGGGCAGCCTCGACGCGGCGCTGC
CCGAGTGCGACGCGGCGGCCTTCGGCCCGGCGACGCTCGCGTACGACATGATGTACGGCGCGCGCCCGACCGTGTTCATG
GAGCACGCCGCGGCGCTCGGCGCGCGCACGGCGGATGGCCTCGGAATGCTCGTCGAGCAGGCCGCGGAATCGTTCCACGT
CTGGCGAGGCGTGCGACCCGACAGCGCGCCCGTGCTCGCCGCGCTGCGCGCCGCGCTCGCGGCGTCGGCCGCGCACTGA

Upstream 100 bases:

>100_bases
CCGACGAATCGGCGCAAGGCGAAGCGGAAGCGCTCGCCGAGGCGGGCGGCGCGGCGAGCGGCAACGGCGAATCGTCCGCG
AACGGCGAGGAACAATCGAA

Downstream 100 bases:

>100_bases
GCGCGGGAGGCGCACGCGGGATGCGCAACAGCCCCGTTTCGCCCGGCCCGGGTTACGCGCCGGCGCGCGGCTCGGAACGC
GCGCGCCGGCGCGGCGTCGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSTAVESAARARDRYAVIGNPIAHSKSPFIHSRFAEQTGEAIEYTHLLAPLDGFSATVRAFIAQGGRGVNVTVPFKLEAY
ALADALSPRAAAAGAVNTLRFDADGVFGDNTDGVGLVRDIEVNLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIV
NRTASKAEELVGQFTQAAHDAGCVLAGGGPERIAREPYDVIVNATAGSLDAALPECDAAAFGPATLAYDMMYGARPTVFM
EHAAALGARTADGLGMLVEQAAESFHVWRGVRPDSAPVLAALRAALAASAAH

Sequences:

>Translated_292_residues
MSTAVESAARARDRYAVIGNPIAHSKSPFIHSRFAEQTGEAIEYTHLLAPLDGFSATVRAFIAQGGRGVNVTVPFKLEAY
ALADALSPRAAAAGAVNTLRFDADGVFGDNTDGVGLVRDIEVNLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIV
NRTASKAEELVGQFTQAAHDAGCVLAGGGPERIAREPYDVIVNATAGSLDAALPECDAAAFGPATLAYDMMYGARPTVFM
EHAAALGARTADGLGMLVEQAAESFHVWRGVRPDSAPVLAALRAALAASAAH
>Mature_291_residues
STAVESAARARDRYAVIGNPIAHSKSPFIHSRFAEQTGEAIEYTHLLAPLDGFSATVRAFIAQGGRGVNVTVPFKLEAYA
LADALSPRAAAAGAVNTLRFDADGVFGDNTDGVGLVRDIEVNLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIVN
RTASKAEELVGQFTQAAHDAGCVLAGGGPERIAREPYDVIVNATAGSLDAALPECDAAAFGPATLAYDMMYGARPTVFME
HAAALGARTADGLGMLVEQAAESFHVWRGVRPDSAPVLAALRAALAASAAH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=49.6402877697842, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1787983, Length=268, Percent_Identity=29.1044776119403, Blast_Score=101, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=163, Percent_Identity=34.3558282208589, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30004; Mature: 29873

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAVESAARARDRYAVIGNPIAHSKSPFIHSRFAEQTGEAIEYTHLLAPLDGFSATVRA
CCHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
FIAQGGRGVNVTVPFKLEAYALADALSPRAAAAGAVNTLRFDADGVFGDNTDGVGLVRDI
HHHCCCCCEEEEECCEEEHHHHHHHCCCHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEE
EVNLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIVNRTASKAEELVGQFTQAAHD
EEECCEEECCCEEEEEECCCCCCCEEEHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
AGCVLAGGGPERIAREPYDVIVNATAGSLDAALPECDAAAFGPATLAYDMMYGARPTVFM
CCEEEECCCHHHHHCCCCEEEEECCCCCCHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
EHAAALGARTADGLGMLVEQAAESFHVWRGVRPDSAPVLAALRAALAASAAH
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STAVESAARARDRYAVIGNPIAHSKSPFIHSRFAEQTGEAIEYTHLLAPLDGFSATVRA
CHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
FIAQGGRGVNVTVPFKLEAYALADALSPRAAAAGAVNTLRFDADGVFGDNTDGVGLVRDI
HHHCCCCCEEEEECCEEEHHHHHHHCCCHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEE
EVNLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIVNRTASKAEELVGQFTQAAHD
EEECCEEECCCEEEEEECCCCCCCEEEHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
AGCVLAGGGPERIAREPYDVIVNATAGSLDAALPECDAAAFGPATLAYDMMYGARPTVFM
CCEEEECCCHHHHHCCCCEEEEECCCCCCHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
EHAAALGARTADGLGMLVEQAAESFHVWRGVRPDSAPVLAALRAALAASAAH
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA