BacMap

Definition	Burkholderia pseudomallei MSHR346 chromosome I, complete genome.
Accession	NC_012695
Length	4,098,576

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The map label for this gene is fabG [H]

Identifier: 237813849

GI number: 237813849

Start: 3501017

End: 3501823

Strand: Reverse

Name: fabG [H]

Synonym: GBP346_A3627

Alternate gene names: 237813849

Gene position: 3501823-3501017 (Counterclockwise)

Preceding gene: 237813850

Following gene: 237813848

Centisome position: 85.44

GC content: 70.26

Gene sequence:

>807_bases
ATGGCTTCGCATCGCGAATCGAATGGCGCGCTCGACGCGCAACACGAGCGTTACGCACGCTACCCGAGCCTCGTCGGCCG
CGCGGTGCTGATCACGGGCGGCGCGACGGGCATCGGCGCGTCGTTCGTCGAGCACTTCGCGCGGCAGGGCGCGCGCGTCG
CGTTCGTCGATCTCGACGAGAAGGCCGGCCGCGCGCTCGTCGCGCGGCTTGCCGACGCCGCGCACGAACCGGTGTTCGTC
GTGTGCGACCTCACCGACATCGGCGCGCTGCGCGGCGCGATCGACGCGATCCGCGTGCGCATCGGCCCGATCGCGGTGCT
CGTCAACAACGCGGCGAACGACGTGCGGCACGCGGTCGCCGACGTGACGCCCGAATCGTTCGACGCGAGCATCGCGGTGA
ATCTGCGTCATCAGTTCTTCGCCGCGCAGGCGGTGATCGACGACATGAAACGGCTGGGCGGCGGCGCGATCGTCAATCTC
GGCTCGATCGGCTGGATGCTGAAGAACGCCGGCTATCCGGTCTACGCGACCGCGAAGGCGGCGGTGCAGGGGCTCACGCG
TGCGCTCGCGCGCGAGCTCGGGCCGTTCGGCATTCGCGTGAACACGCTCGTGCCGGGCTGGGTGATGACCGACAAGCAAC
GCCGCTTGTGGCTCGACGATGCGGGCCGCGCGGCGATCAAGGCGGGGCAGTGCATCGACGCCGAACTGCTGCCGGGCGAT
CTCGCGCGCATGGCGCTCTTTCTCGCCGCGGACGACAGCCGGCTGATCACCGCGCAGGACGTTGTCGTCGACGGCGGCTG
GGCATAG

Upstream 100 bases:

>100_bases
GCGCGATCCTGCTCGCCGCCGTGCTGCTCGACCAGCTGAAGAACCGCGGCGCGCGCGATTGAGCGCGGCGCCCATTTCCG
GGAACGAACAGGTAAACGAC

Downstream 100 bases:

>100_bases
CATTCGTGCGGATGACCAAACGCGACGAAAGCAGGAGGACCGAATCATGACGGCGACGCATTCTCGATCCACAGCCACCG
ATGCGGTGCAAACCTTGCAG

Product: oxidoreductase, short chain dehydrogenase/reductase family

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MASHRESNGALDAQHERYARYPSLVGRAVLITGGATGIGASFVEHFARQGARVAFVDLDEKAGRALVARLADAAHEPVFV
VCDLTDIGALRGAIDAIRVRIGPIAVLVNNAANDVRHAVADVTPESFDASIAVNLRHQFFAAQAVIDDMKRLGGGAIVNL
GSIGWMLKNAGYPVYATAKAAVQGLTRALARELGPFGIRVNTLVPGWVMTDKQRRLWLDDAGRAAIKAGQCIDAELLPGD
LARMALFLAADDSRLITAQDVVVDGGWA

Sequences:

>Translated_268_residues
MASHRESNGALDAQHERYARYPSLVGRAVLITGGATGIGASFVEHFARQGARVAFVDLDEKAGRALVARLADAAHEPVFV
VCDLTDIGALRGAIDAIRVRIGPIAVLVNNAANDVRHAVADVTPESFDASIAVNLRHQFFAAQAVIDDMKRLGGGAIVNL
GSIGWMLKNAGYPVYATAKAAVQGLTRALARELGPFGIRVNTLVPGWVMTDKQRRLWLDDAGRAAIKAGQCIDAELLPGD
LARMALFLAADDSRLITAQDVVVDGGWA
>Mature_267_residues
ASHRESNGALDAQHERYARYPSLVGRAVLITGGATGIGASFVEHFARQGARVAFVDLDEKAGRALVARLADAAHEPVFVV
CDLTDIGALRGAIDAIRVRIGPIAVLVNNAANDVRHAVADVTPESFDASIAVNLRHQFFAAQAVIDDMKRLGGGAIVNLG
SIGWMLKNAGYPVYATAKAAVQGLTRALARELGPFGIRVNTLVPGWVMTDKQRRLWLDDAGRAAIKAGQCIDAELLPGDL
ARMALFLAADDSRLITAQDVVVDGGWA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=32.2709163346614, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=35.4581673306773, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=32.2709163346614, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=32.6424870466321, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=25.968992248062, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=28.2700421940928, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=30.3501945525292, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=26.7716535433071, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=28.3261802575107, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=30.5263157894737, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=30.9941520467836, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4503817, Length=207, Percent_Identity=26.5700483091787, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=30, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI302344755, Length=103, Percent_Identity=37.8640776699029, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI210032110, Length=211, Percent_Identity=26.0663507109005, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=24.2798353909465, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=32.4, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=30.7377049180328, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=31.5573770491803, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=27.2357723577236, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=29.5275590551181, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=31.6, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=28.90625, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=29.6747967479675, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=189, Percent_Identity=31.2169312169312, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=26.0869565217391, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=31.2757201646091, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=29.3436293436293, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=30.9963099630996, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=28.4552845528455, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=28.6792452830189, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=28.2258064516129, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=29.4736842105263, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=30.1470588235294, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=29.368029739777, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=27.8625954198473, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=27.2357723577236, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=30, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=27.6515151515151, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=28.6245353159851, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=27.6752767527675, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=29.368029739777, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=27.2373540856031, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=187, Percent_Identity=26.2032085561497, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=26.2032085561497, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=26.6932270916335, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=27.037037037037, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=26.9662921348315, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=27.2373540856031, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=25.4980079681275, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=202, Percent_Identity=28.7128712871287, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=25.3968253968254, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.7086614173228, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=28.9156626506024, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=28.9156626506024, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=29.8387096774194, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=31.2, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=27.710843373494, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644337, Length=246, Percent_Identity=30.0813008130081, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364892, Length=185, Percent_Identity=32.4324324324324, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=25.8823529411765, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737361, Length=201, Percent_Identity=30.3482587064677, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24584752, Length=224, Percent_Identity=29.0178571428571, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640492, Length=219, Percent_Identity=26.9406392694064, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356301, Length=208, Percent_Identity=27.4038461538462, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581726, Length=200, Percent_Identity=26.5, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28401; Mature: 28270

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASHRESNGALDAQHERYARYPSLVGRAVLITGGATGIGASFVEHFARQGARVAFVDLDE
CCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCC
KAGRALVARLADAAHEPVFVVCDLTDIGALRGAIDAIRVRIGPIAVLVNNAANDVRHAVA
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHEECEEEEEEECCHHHHHHHHH
DVTPESFDASIAVNLRHQFFAAQAVIDDMKRLGGGAIVNLGSIGWMLKNAGYPVYATAKA
HCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCEEEHHHH
AVQGLTRALARELGPFGIRVNTLVPGWVMTDKQRRLWLDDAGRAAIKAGQCIDAELLPGD
HHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCEEEECCCCCHHHHCCCCCCCCCCCHH
LARMALFLAADDSRLITAQDVVVDGGWA
HHHHEEEEECCCCCEEEEEEEEECCCCC
>Mature Secondary Structure 
ASHRESNGALDAQHERYARYPSLVGRAVLITGGATGIGASFVEHFARQGARVAFVDLDE
CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCC
KAGRALVARLADAAHEPVFVVCDLTDIGALRGAIDAIRVRIGPIAVLVNNAANDVRHAVA
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHEECEEEEEEECCHHHHHHHHH
DVTPESFDASIAVNLRHQFFAAQAVIDDMKRLGGGAIVNLGSIGWMLKNAGYPVYATAKA
HCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCEEEHHHH
AVQGLTRALARELGPFGIRVNTLVPGWVMTDKQRRLWLDDAGRAAIKAGQCIDAELLPGD
HHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCEEEECCCCCHHHHCCCCCCCCCCCHH
LARMALFLAADDSRLITAQDVVVDGGWA
HHHHEEEEECCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]