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The map label for this gene is tkt [H]

Identifier: 237813834

GI number: 237813834

Start: 3487883

End: 3489955

Strand: Reverse

Name: tkt [H]

Synonym: GBP346_A3612

Alternate gene names: 237813834

Gene position: 3489955-3487883 (Counterclockwise)

Preceding gene: 237813835

Following gene: 237813833

Centisome position: 85.15

GC content: 68.31

Gene sequence:

>2073_bases
ATGCCGCCCGTGCCCCGTTTTCTCGACTCGTTCTCCGGACTCGACATGACGACTTCGTCTCCCGCCTCCACCACTCTGAT
GGCCAACGCGATCCGCGCGCTCGCGATGGACGCCGTCCAGCAAGCGAACTCCGGCCACCCCGGCATGCCGATGGGCATGG
CCGAGATCGGCGTCGCGCTGTGGTCGCGCCACCTGAAGCACAACCCGACGAACCCGCATTGGGCCGACCGCGACCGCTTC
GTGCTGTCGAACGGCCACGGCTCGATGCTGCTGTACTCGCTGCTGCACCTGACGGGCTACGATCTGCCGATCGAAGAGCT
GAAGAATTTCCGGCAATTGCATTCGAAGACGCCGGGCCACCCGGAATACGGGATCACGCCGGGCGTCGAGACGACGACGG
GCCCGCTCGGCCAGGGCCTCGCGAACGCGGTCGGCATGGCGCTCGGCGAGGCGCTGCTCGCCGCCGAGTTCAACCGCGAC
GACGCGAAGATCGTCGATCATCACACGTACGTGTTCGTCGGCGACGGCTGCCTGATGGAGGGCATCTCGCACGAAGCGTG
CTCGCTCGCGGGCACGCTCAAGCTCAACAAGCTGATCGCGTTCTACGACGACAACGGGATCTCGATCGACGGCGACGTCG
TCAACTGGTTCCACGACGACACGCCGAAGCGCTTCGAGGCGTACGGCTGGAACGTGATTCCGAACGTGAACGGCCACGAC
GTCGACGCGGTCGATGCCGCGATCGCGAAGGCGAAGAGCGCGGACAAGCCGACGCTCATCTGCTGCAAGACGGTGATCGG
CAAGGGCGCGGCGACGAAGGCGGGCGGCCACGACGTGCACGGCGCGGCGCTCGGCGCGGAGGAAATCGCGAAGACGCGCG
ACGCGCTCGGCTGGAAGTGGGCGCCGTTCGTGATTCCGCAGGAAGTCTACGCGGCGTGGGACGCGAAGGAAGCGGGCAAG
CGCCGCGAAGGCGACTGGAACGCGGCGTTCGCGCAGTACCGCGCGAAGTACCCGGCCGAGGCCGCCGAATTCGAGCGCCG
CATGGCGGGCAAGCTGCCGGCCGACTGGGCCGAGAAGGCCGCGGCGATCGTCGCCGGCGCGAACGAGCGCGGCGAGACGG
TCGCGACGCGCAAGGCGTCGCAGCAGACGATCGAGGGCCTTGCCGCCGTGCTGCCCGAGCTGCTCGGCGGCTCGGCCGAC
CTGACGGGCTCGAACCTCACGAACTGGAAGGCGTCGAAGGCGGTGCGCGCGAATGCGCACGGCGCGGGCATCCAGTGGGG
CAACCACATCAACTACGGCGTGCGCGAATTCGGCATGAGCGCCGCGATCAACGGCCTCGTGCTGCACGGCGGCTACAAGC
CGTTCGGCGGCACGTTCCTCACGTTCTCCGACTACAGCCGCAACGCGCTGCGCGTCGCCGCGCTGATGAAGGTGCCGTCG
ATCTTCGTGTTCACGCACGATTCGATCGGCCTCGGCGAAGACGGGCCGACGCACCAGTCGGTCGAGCACGTCGCGAGCCT
GCGGCTGATTCCGAACCTCGACGTCTGGCGCCCGGCCGACACGGTCGAGACGGCGGTCGCGTGGACCCACGCGGTCTCGC
ACCAGCACCCGTCGTGCCTGGTCTTCAGCCGCCAGAACCTCGCGTTCAACGCGCGCACCGACGCGCAGCTCGCGAACATC
GAGAAGGGCGGCTACGTGCTGCGCGACTGGGACGAAGAGATCGTCGCGCGCAAGATCATCCTGATCGCGACGGGCTCGGA
AGTGGAGCTCGCGATGAAGGCGGTCGAGCCGCTCGCGCAGCAGGGGATCGCCGCGCGCGTCGTGTCGATGCCGTCGACCG
ACGTGTTCGACCGGCAGGACGCCGAGTACCGCGAGCGCGTGCTGCCGCACGGCGTGCGCCGCGTCGCGATCGAAGCGGGC
GTCACCGATTTCTGGCGCAAGTACGTGGGCCTCGAAGGCGGCGTGGTCGGCATCGACACGTTCGGCGAGTCGGCTCCGGC
TGGCGTGTTGTTCAAGCATTTCGGCTTCACGATCGAGCACGTGGTCGAAACGGCGAAGGCGGTGCTCGCGTAA

Upstream 100 bases:

>100_bases
TTAAAATGACCAGCTTTGCAGCCTCGTCCGTCTGCTCGTCCGCTTCGCCTCCCGCCGGCGCCGCACCGCGCGCCGGAAAC
GGTTGGCCCGCGAGCCTCGG

Downstream 100 bases:

>100_bases
CCCATTCGACGCCCGGGCGGCCGTGCCCCGCGCCGGCCGGGCGCGCGTGAAGCTGCACGAAGTATTTTTTCAGCCATCAG
GAGATACATCATGACGATTC

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MPPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRD
DAKIVDHHTYVFVGDGCLMEGISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAVDAAIAKAKSADKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDAKEAGK
RREGDWNAAFAQYRAKYPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSAD
LTGSNLTNWKASKAVRANAHGAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDAQLANI
EKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAG
VTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFGFTIEHVVETAKAVLA

Sequences:

>Translated_690_residues
MPPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRD
DAKIVDHHTYVFVGDGCLMEGISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAVDAAIAKAKSADKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDAKEAGK
RREGDWNAAFAQYRAKYPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSAD
LTGSNLTNWKASKAVRANAHGAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDAQLANI
EKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAG
VTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFGFTIEHVVETAKAVLA
>Mature_689_residues
PPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFV
LSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDD
AKIVDHHTYVFVGDGCLMEGISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDV
DAVDAAIAKAKSADKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDAKEAGKR
REGDWNAAFAQYRAKYPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADL
TGSNLTNWKASKAVRANAHGAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPSI
FVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDAQLANIE
KGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAGV
TDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFGFTIEHVVETAKAVLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=607, Percent_Identity=27.1828665568369, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4507521, Length=607, Percent_Identity=27.1828665568369, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI133778974, Length=263, Percent_Identity=33.0798479087452, Blast_Score=109, Evalue=1e-23,
Organism=Escherichia coli, GI48994911, Length=671, Percent_Identity=63.6363636363636, Blast_Score=877, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=61.4114114114114, Blast_Score=823, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=680, Percent_Identity=26.0294117647059, Blast_Score=154, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6325331, Length=672, Percent_Identity=49.702380952381, Blast_Score=613, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319593, Length=674, Percent_Identity=45.6973293768546, Blast_Score=557, Evalue=1e-159,
Organism=Drosophila melanogaster, GI24666278, Length=263, Percent_Identity=34.2205323193916, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45551847, Length=309, Percent_Identity=32.3624595469256, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI45550715, Length=309, Percent_Identity=32.3624595469256, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24645119, Length=260, Percent_Identity=33.0769230769231, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74355; Mature: 74224

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFVGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCHHHH
GISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCC
VDAVDAAIAKAKSADKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKW
CHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCC
APFVIPQEVYAAWDAKEAGKRREGDWNAAFAQYRAKYPAEAAEFERRMAGKLPADWAEKA
CCCCCCHHHHHHCCHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHH
AAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAVRANAH
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCC
GAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
CCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCL
EEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
VFSRQNLAFNARTDAQLANIEKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCEEECCCCCHHHCCCCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKHFGFTIEHVVETAKAVLA
CCCCCCCHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFVGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCHHHH
GISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCC
VDAVDAAIAKAKSADKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKW
CHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCC
APFVIPQEVYAAWDAKEAGKRREGDWNAAFAQYRAKYPAEAAEFERRMAGKLPADWAEKA
CCCCCCHHHHHHCCHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHH
AAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAVRANAH
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCC
GAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
CCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCL
EEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
VFSRQNLAFNARTDAQLANIEKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCEEECCCCCHHHCCCCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKHFGFTIEHVVETAKAVLA
CCCCCCCHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA