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The map label for this gene is exuR [H]

Identifier: 237813826

GI number: 237813826

Start: 3481383

End: 3482075

Strand: Direct

Name: exuR [H]

Synonym: GBP346_A3604

Alternate gene names: 237813826

Gene position: 3481383-3482075 (Clockwise)

Preceding gene: 237813822

Following gene: 237813827

Centisome position: 84.94

GC content: 66.52

Gene sequence:

>693_bases
ATGAAGAACGTTCCGCATACCGTCACCGACGCCGCCATCGCCACGATCCGTGAGCGGATCGAGCGCGGCTTCTATCCCGT
CGGCAGCCTGTTGCCCGCGCAACGTCAATTGTCCGAAGAACTGGAAATCAGCCGCGCGTCGCTGCGCGAGGCGCTGTCGA
CGCTCGAGGCGCTCGGCATGCTGCGCATCCGGCCCGGCAAGGGCGTGTACGTCGAAAGCGCGCAGGCGAGCGCCGCGCAT
GCGTGGCGCTTCGCCGAGCAGTCTTCGCTGCCCGACACCTACCAGATGCGCTATGCGCTCGAAGGCTTCGCCGCGCGAAT
GGCCGCGCTCGCCGTCAGCGAGGAGGATCTCGCGTGGTTCGAGGAGAATGTCGCCGCGCTGCAGGAGGCGCTCGCGAACG
ACGAGCTCGATAGCGCATCGCAGCTCGATTTCGATTTCCACATGCGCATCGTCAGCCTCGCCGGCAACGCGGCGATCGAA
TCGATCCTGCGCGGCAGCGCGGACATCATGAAGGAAAGCCAGCGGATGCCGTTCTATCGGCGCGAGCTCGTGCTTTCGAC
GTATCGCGAGCATCGCGCGATTCTCGATGCGCTGATCGCGAAGGATCCCGCCGCGGCGGGCGCGGCGATCGAAGCGCACA
TCTCGAACGCCGCGCAGCGCGCGGGCGTGTTCTTTCCGACGCCGAAGCGCTGA

Upstream 100 bases:

>100_bases
CGGGCGCGGCGCACGCCGGATCATCGCTTTCCCGGAGCTCGGGCGCGCGGCGGCGGGGCCGGTTTACAATGCCGGTCAGA
CCGCGCAATCGATCCACTGC

Downstream 100 bases:

>100_bases
CGCGGCGCATGCGTGCTCGTGCGCGGGGCGGCATACGGCGCACGGGCGCGCGGGCGTTGCGCCGTCCGCGCGCATTTGCG
CAAGCGCCGGCGCGGCGTGC

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKNVPHTVTDAAIATIRERIERGFYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRPGKGVYVESAQASAAH
AWRFAEQSSLPDTYQMRYALEGFAARMAALAVSEEDLAWFEENVAALQEALANDELDSASQLDFDFHMRIVSLAGNAAIE
SILRGSADIMKESQRMPFYRRELVLSTYREHRAILDALIAKDPAAAGAAIEAHISNAAQRAGVFFPTPKR

Sequences:

>Translated_230_residues
MKNVPHTVTDAAIATIRERIERGFYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRPGKGVYVESAQASAAH
AWRFAEQSSLPDTYQMRYALEGFAARMAALAVSEEDLAWFEENVAALQEALANDELDSASQLDFDFHMRIVSLAGNAAIE
SILRGSADIMKESQRMPFYRRELVLSTYREHRAILDALIAKDPAAAGAAIEAHISNAAQRAGVFFPTPKR
>Mature_230_residues
MKNVPHTVTDAAIATIRERIERGFYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRPGKGVYVESAQASAAH
AWRFAEQSSLPDTYQMRYALEGFAARMAALAVSEEDLAWFEENVAALQEALANDELDSASQLDFDFHMRIVSLAGNAAIE
SILRGSADIMKESQRMPFYRRELVLSTYREHRAILDALIAKDPAAAGAAIEAHISNAAQRAGVFFPTPKR

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=215, Percent_Identity=30.2325581395349, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790032, Length=236, Percent_Identity=29.6610169491525, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790780, Length=215, Percent_Identity=29.7674418604651, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786303, Length=196, Percent_Identity=31.1224489795918, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1789353, Length=225, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25348; Mature: 25348

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVPHTVTDAAIATIRERIERGFYPVGSLLPAQRQLSEELEISRASLREALSTLEALGM
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LRIRPGKGVYVESAQASAAHAWRFAEQSSLPDTYQMRYALEGFAARMAALAVSEEDLAWF
EEECCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
EENVAALQEALANDELDSASQLDFDFHMRIVSLAGNAAIESILRGSADIMKESQRMPFYR
HHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
RELVLSTYREHRAILDALIAKDPAAAGAAIEAHISNAAQRAGVFFPTPKR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKNVPHTVTDAAIATIRERIERGFYPVGSLLPAQRQLSEELEISRASLREALSTLEALGM
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LRIRPGKGVYVESAQASAAHAWRFAEQSSLPDTYQMRYALEGFAARMAALAVSEEDLAWF
EEECCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
EENVAALQEALANDELDSASQLDFDFHMRIVSLAGNAAIESILRGSADIMKESQRMPFYR
HHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
RELVLSTYREHRAILDALIAKDPAAAGAAIEAHISNAAQRAGVFFPTPKR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA