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The map label for this gene is gltK [H]

Identifier: 237813796

GI number: 237813796

Start: 3452973

End: 3453650

Strand: Reverse

Name: gltK [H]

Synonym: GBP346_A3574

Alternate gene names: 237813796

Gene position: 3453650-3452973 (Counterclockwise)

Preceding gene: 237813797

Following gene: 237813795

Centisome position: 84.26

GC content: 64.31

Gene sequence:

>678_bases
ATGCATCAGTTCGACTGGAGTAGTATCCCCGGCGCGCTGCCGACGCTCTGGACGGGCGCGGTCGTCACGTTCAAGATCAC
GCTGCTCGCGATCGTGATCGGCATCGTCTGGGGCACGTTGCTCGCGCTGATGCGCCTGTCGGGCGTGAAGCCGCTCGCGT
GGTTCGCGCAGGGCTACGTCACCGTGTTCCGCTCGATCCCGCTCGTGATGGTGCTGCTGTGGTTTTTCCTGATCGTGCCG
CAGTTGCTGCAGGGCGTGCTCGGGCTGTCGCCGACGATCGACATCCGGCTCGCCTCGGCGATGGTGGCGTTCTCGCTGTT
CGAGGCCGCGTATTATTCGGAGATCATCCGCGCGGGCATTCAGGCGGTGCCGCGCGGGCAGGTGAACGCCGCGTTTGCGC
TCGGCATGAACTATGCGCAGGCGATGCGCCTCGTGATCCTGCCGCAGGCGTTTCGCGCGATGGTGCCGCTGCTGCTCACG
CAGGCGATCGTGCTGTTCCAGGACACGTCGCTCGTCTACGTGATCAGCCTCGCGGACTTCTTCCGCACGGCCGCGAACAT
CGGCGATCGCGACGGCACGAGCGTCGAGATGATCCTGTTCGCGGGCGCATGCTATTTCGTCGTGTGCTCGGTCGCATCCG
CGTTGGTCAAAGGTCTCCAGAAAAAGGTCACAAGATGA

Upstream 100 bases:

>100_bases
CGGTCACGCTCGCGTACGTGGTGATCAACCTGATCGTGATGACGTTCATGCGCTGGGTCGAGAGCAAATCCCGGCTGCCC
GGCTACATCGGAGGCAAGTG

Downstream 100 bases:

>100_bases
TTTCCATTAAGAACGTGTCGAAGTGGTACGGCCAGTTTCAGGTGCTGACGGACTGCACGACGGAAGTGAAGAAGGGCGAG
GTGGTGGTCGTGTGCGGGCC

Product: glutamate/aspartate ABC transporter, permease protein GltK

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MHQFDWSSIPGALPTLWTGAVVTFKITLLAIVIGIVWGTLLALMRLSGVKPLAWFAQGYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTAANIGDRDGTSVEMILFAGACYFVVCSVASALVKGLQKKVTR

Sequences:

>Translated_225_residues
MHQFDWSSIPGALPTLWTGAVVTFKITLLAIVIGIVWGTLLALMRLSGVKPLAWFAQGYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTAANIGDRDGTSVEMILFAGACYFVVCSVASALVKGLQKKVTR
>Mature_225_residues
MHQFDWSSIPGALPTLWTGAVVTFKITLLAIVIGIVWGTLLALMRLSGVKPLAWFAQGYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTAANIGDRDGTSVEMILFAGACYFVVCSVASALVKGLQKKVTR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=72.0720720720721, Blast_Score=321, Evalue=2e-89,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=36.4485981308411, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI87082239, Length=210, Percent_Identity=34.2857142857143, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786874, Length=187, Percent_Identity=32.620320855615, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787030, Length=225, Percent_Identity=29.7777777777778, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787087, Length=227, Percent_Identity=27.3127753303965, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=26.7281105990783, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI48994930, Length=129, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788646, Length=208, Percent_Identity=25.4807692307692, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=24.2990654205607, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24537; Mature: 24537

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQFDWSSIPGALPTLWTGAVVTFKITLLAIVIGIVWGTLLALMRLSGVKPLAWFAQGYV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TVFRSIPLVMVLLWFFLIVPQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLADF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FRTAANIGDRDGTSVEMILFAGACYFVVCSVASALVKGLQKKVTR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHQFDWSSIPGALPTLWTGAVVTFKITLLAIVIGIVWGTLLALMRLSGVKPLAWFAQGYV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TVFRSIPLVMVLLWFFLIVPQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLADF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FRTAANIGDRDGTSVEMILFAGACYFVVCSVASALVKGLQKKVTR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]