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The map label for this gene is ubiA [H]

Identifier: 237813715

GI number: 237813715

Start: 3380526

End: 3381389

Strand: Reverse

Name: ubiA [H]

Synonym: GBP346_A3492

Alternate gene names: 237813715

Gene position: 3381389-3380526 (Counterclockwise)

Preceding gene: 237813716

Following gene: 237813711

Centisome position: 82.5

GC content: 65.74

Gene sequence:

>864_bases
ATGCTCGCCCGTTTTCCCCTCTATTTGCGGCTGATCCGGATGGACAAGCCGATCGGCAGCCTGCTGCTGCTCTGGCCGAC
GCTCAATGCGCTGTGGATCGCGTCCGACGGCCATCCTGCGCCGTCGCTCGTCGCGATCTTCGCGCTCGGCACGCTGCTGA
TGCGCTCGGCCGGCTGCGCGATCAACGATTACGCCGATCGCGATTTCGACCGCCACGTGAAGCGCACCGCCGAGCGGCCG
CTCACGTCGGGCAAGATCCGCGCATGGGAGGCGATCGCGATCGCGGTCGGTCTCGCGCTCGTGTCGTTTCTGCTGATCCT
GCCGCTCAACGGGCTGACGAAGGAGCTGTCCGTCGTCGCGGTGTTCGTCGCGGCGACCTACCCGTTCATGAAGCGCTTCT
TCGCGATTCCGCAGGCGTATCTCGGCATCGCGTTCGGCTTCGGGATTCCGATGGCGTTCGCGGCCGTGCAGGATACGGTG
CCGATGATCGCTTGGGCGATGCTCGCGGCCAACGTGTTCTGGTCGGTTGCGTACGACACCGCGTATGCGATGGTCGATCG
CGACGACGATCTGAAGATCGGCATGCGCACGTCGGCGATCACGTTCGGCCGCCATGACGTGCTCGCGATCATGCTCTGCT
ACGCGGCGATGCTCGGCATCTACGTGTGGCTCGGCGCGGCGCTGCATTTCGGTTGGCCGTATTGGGCGGGCTGGGCGGCG
GCGGCCGGCTGCGCGATCTACCATTACACGCTGATCAAGGATCGCGAGCGGATGGCGTGCTTCGCCGCGTTCAGGCACAA
CAACTGGTTGGGCGGCGTGCTTTTCGCGGGGATCGCCGCGCATTACGCGCTCGCCGTGCGGTAA

Upstream 100 bases:

>100_bases
ACAAAAAAGGGCGATGGCGCGGCCCGGCGTTTTGCCGCGAATCCCGCGCGGTTCTACAATGCCGGGGTTACGTTCGAGGG
CTCGCCGCCCGTTCTCGCCG

Downstream 100 bases:

>100_bases
GCGGCGGGCCGGCGGGCGCGGTGCGCTCGGGCGCGATCGGGAAGCGGCCTGCGGGCCGCTTTCTTTTTGGGGCGATGCTT
TGGGGGGCGAGGCGGGCGTG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVAIFALGTLLMRSAGCAINDYADRDFDRHVKRTAERP
LTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAAMLGIYVWLGAALHFGWPYWAGWAA
AAGCAIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR

Sequences:

>Translated_287_residues
MLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVAIFALGTLLMRSAGCAINDYADRDFDRHVKRTAERP
LTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAAMLGIYVWLGAALHFGWPYWAGWAA
AAGCAIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR
>Mature_287_residues
MLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVAIFALGTLLMRSAGCAINDYADRDFDRHVKRTAERP
LTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAAMLGIYVWLGAALHFGWPYWAGWAA
AAGCAIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=275, Percent_Identity=33.4545454545455, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1790473, Length=273, Percent_Identity=53.4798534798535, Blast_Score=280, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI17553718, Length=280, Percent_Identity=33.5714285714286, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32565247, Length=280, Percent_Identity=32.1428571428571, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17553720, Length=337, Percent_Identity=28.7833827893175, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=40.8759124087591, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=40.6015037593985, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324370, Length=295, Percent_Identity=28.4745762711864, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355567, Length=274, Percent_Identity=33.5766423357664, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 31645; Mature: 31645

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVAIFALGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
INDYADRDFDRHVKRTAERPLTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVA
CCCHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMIAWAMLAANVFWSVAYDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAAMLGIYVWLGAALHFGWPYWAGWAA
HEEEECCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAGCAIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVAIFALGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
INDYADRDFDRHVKRTAERPLTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVA
CCCHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMIAWAMLAANVFWSVAYDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAAMLGIYVWLGAALHFGWPYWAGWAA
HEEEECCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAGCAIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA