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The map label for this gene is glcD [H]

Identifier: 237813697

GI number: 237813697

Start: 3362534

End: 3364027

Strand: Direct

Name: glcD [H]

Synonym: GBP346_A3474

Alternate gene names: 237813697

Gene position: 3362534-3364027 (Clockwise)

Preceding gene: 237813696

Following gene: 237813698

Centisome position: 82.04

GC content: 69.14

Gene sequence:

>1494_bases
ATGAACGCCCCCGCCGAACTGTCGGCCGATCTGCGCGCGCAGCGCCAGCGCGAAGTCGTGCAGGCGCTGATGGCCGTGCT
GCCGACCCATTGCCTGCTGCATCGCGACGAGGACACGGCCGCGTACGAATGCGATGCGCTGTCCGCATACCGCCGGCTGC
CGCTCGCGGTGGCGCTGCCGGAGACCGAATCGCAGGTGCAGCGGATCGTGCAGATCTGCCGGCGCATGAACGTGCCGATC
GTGCCGCGCGGCGCGGGCACGAGCCTGTCGGGCGGCGCGCTGCCGATCGGGCACGGCGTCGTGCTGTCGCTCGCGCGCTT
CACGCGGATCGTCGAAGTCGATTCCTATGCGCGCACGGCCACCGTTCAGCCCGGCGTGCGCAATCTCGCGATCTCCGAGG
CCGCCGCGCCGTACGGCCTCTACTACGCGCCCGATCCCTCGTCGCAGATCGCGTGCACGATCGGCGGCAACGTGTCGGAG
AACTCGGGCGGCGTTCATTGCCTGAAATACGGGCTCACATGCCATAACGTGCTGCGCGTGCGCGGCGTGACGATCGACGG
CGAGATCGTCGAGTTCGGCTCGCTCGCGCCCGACGTGCCGGGCCTCGATCTGCTCACCGTCACGATCGGCAGCGAAGGCA
TGTTCATCGTCGTCACCGAGGTGACGGTGCGGCTGATCCCGAAGCCGCAGTGCGCGCAGCTCGTGATGGCGAGCTTCGAC
GACGTCGTCAAGGGCGGCGAGGCCGTTGCCGCGATCATCGCGTCGGGCATCATTCCGGCCGGGCTCGAGATGATGGACAA
GCCCGCGACGCAGGCGGTCGAGGCGTTCACGCACGCGGGCTACGATCTCGACGCGGCCGCGATCCTGCTGTGCGAATCGG
ACGGCACACAGGAGGAAGTCGCCGAGGAGATCGTGCGGATGACCGCGGTGCTGCGCGAGCACGGCGCGACGCGCATCCAG
GTCTCGCGCAGCGAGGCCGAGCGGCTGCGCTTCTGGTCGGGCCGCAAGAACGCGTTCCCGGCCGCGGGCCGCATTTCGCC
CGACTATTACTGCATGGACGGCACGGTGCCGCGCCGCGCGATCGGGCCGCTCCTCGCGCGCATCGAGCAGATGGAGACGA
AGTACGGGCTGCGCTGCATCAACGTGTTCCACGCGGGCGACGGCAACATGCACCCGCTCATCCTGTTCAACGCGAACGAC
GTCGACGAGCTGCACCGCGCGGAGGCGTTCGGCGCGGACATCCTCGAGACCTGCGTCGAATTCGGCGGCACGGTGACGGG
CGAGCACGGCGTCGGCGTCGAGAAGCTGAACTCGATGTGCGTGCAGTTCTCGCGCGAGGAGTGCGATGCGTTCTTCGCGG
TCAAGCGCGCGTTCGATCCGCCCGAGCTGCTGAATCCGGACAAGGGCATTCCGACCCGCGCGCGCTGCGCCGAATACGGC
CGGATGCACGTGCGCGGCGGGCTGCTGCCGCATCCGGACCTGCCGCGCTTTTGA

Upstream 100 bases:

>100_bases
ATGAACCCCGGCAAGATCTTCACGATCGACGCATGAAAACGACGGCGCCCGCGACGAGCCCGAACCGCCGCGCGCCGTGC
GCCGCGCAACAGGAGAAGAC

Downstream 100 bases:

>100_bases
CGCCGCGCGCGGGCCCCAAGCGGATCGTAGGGGTTCGGCCCGACTGTGCGATCGCGCCGCCCCGGTAGAATCGACCGAAA
CGAACAACGAAACACAACGC

Product: glycolate oxidase, subunit GlcD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNAPAELSADLRAQRQREVVQALMAVLPTHCLLHRDEDTAAYECDALSAYRRLPLAVALPETESQVQRIVQICRRMNVPI
VPRGAGTSLSGGALPIGHGVVLSLARFTRIVEVDSYARTATVQPGVRNLAISEAAAPYGLYYAPDPSSQIACTIGGNVSE
NSGGVHCLKYGLTCHNVLRVRGVTIDGEIVEFGSLAPDVPGLDLLTVTIGSEGMFIVVTEVTVRLIPKPQCAQLVMASFD
DVVKGGEAVAAIIASGIIPAGLEMMDKPATQAVEAFTHAGYDLDAAAILLCESDGTQEEVAEEIVRMTAVLREHGATRIQ
VSRSEAERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRAIGPLLARIEQMETKYGLRCINVFHAGDGNMHPLILFNAND
VDELHRAEAFGADILETCVEFGGTVTGEHGVGVEKLNSMCVQFSREECDAFFAVKRAFDPPELLNPDKGIPTRARCAEYG
RMHVRGGLLPHPDLPRF

Sequences:

>Translated_497_residues
MNAPAELSADLRAQRQREVVQALMAVLPTHCLLHRDEDTAAYECDALSAYRRLPLAVALPETESQVQRIVQICRRMNVPI
VPRGAGTSLSGGALPIGHGVVLSLARFTRIVEVDSYARTATVQPGVRNLAISEAAAPYGLYYAPDPSSQIACTIGGNVSE
NSGGVHCLKYGLTCHNVLRVRGVTIDGEIVEFGSLAPDVPGLDLLTVTIGSEGMFIVVTEVTVRLIPKPQCAQLVMASFD
DVVKGGEAVAAIIASGIIPAGLEMMDKPATQAVEAFTHAGYDLDAAAILLCESDGTQEEVAEEIVRMTAVLREHGATRIQ
VSRSEAERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRAIGPLLARIEQMETKYGLRCINVFHAGDGNMHPLILFNAND
VDELHRAEAFGADILETCVEFGGTVTGEHGVGVEKLNSMCVQFSREECDAFFAVKRAFDPPELLNPDKGIPTRARCAEYG
RMHVRGGLLPHPDLPRF
>Mature_497_residues
MNAPAELSADLRAQRQREVVQALMAVLPTHCLLHRDEDTAAYECDALSAYRRLPLAVALPETESQVQRIVQICRRMNVPI
VPRGAGTSLSGGALPIGHGVVLSLARFTRIVEVDSYARTATVQPGVRNLAISEAAAPYGLYYAPDPSSQIACTIGGNVSE
NSGGVHCLKYGLTCHNVLRVRGVTIDGEIVEFGSLAPDVPGLDLLTVTIGSEGMFIVVTEVTVRLIPKPQCAQLVMASFD
DVVKGGEAVAAIIASGIIPAGLEMMDKPATQAVEAFTHAGYDLDAAAILLCESDGTQEEVAEEIVRMTAVLREHGATRIQ
VSRSEAERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRAIGPLLARIEQMETKYGLRCINVFHAGDGNMHPLILFNAND
VDELHRAEAFGADILETCVEFGGTVTGEHGVGVEKLNSMCVQFSREECDAFFAVKRAFDPPELLNPDKGIPTRARCAEYG
RMHVRGGLLPHPDLPRF

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=421, Percent_Identity=28.2660332541568, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI37595754, Length=445, Percent_Identity=27.6404494382022, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI119964728, Length=453, Percent_Identity=24.9448123620309, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI4501993, Length=235, Percent_Identity=28.5106382978723, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI1789351, Length=479, Percent_Identity=59.7077244258873, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1787977, Length=515, Percent_Identity=24.2718446601942, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI48994907, Length=451, Percent_Identity=22.6164079822616, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71992373, Length=425, Percent_Identity=25.4117647058824, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI71992381, Length=425, Percent_Identity=24.2352941176471, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71992392, Length=358, Percent_Identity=25.1396648044693, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17534361, Length=449, Percent_Identity=24.9443207126949, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17556096, Length=456, Percent_Identity=21.4912280701754, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320027, Length=432, Percent_Identity=26.3888888888889, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320023, Length=460, Percent_Identity=28.0434782608696, Blast_Score=146, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6320764, Length=462, Percent_Identity=25.5411255411255, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI18921117, Length=444, Percent_Identity=27.027027027027, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24639277, Length=444, Percent_Identity=27.027027027027, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24639275, Length=444, Percent_Identity=27.027027027027, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24653753, Length=223, Percent_Identity=28.2511210762332, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 53660; Mature: 53660

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPAELSADLRAQRQREVVQALMAVLPTHCLLHRDEDTAAYECDALSAYRRLPLAVALP
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHCCEEEECC
ETESQVQRIVQICRRMNVPIVPRGAGTSLSGGALPIGHGVVLSLARFTRIVEVDSYARTA
CCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCEE
TVQPGVRNLAISEAAAPYGLYYAPDPSSQIACTIGGNVSENSGGVHCLKYGLTCHNVLRV
ECCCCHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHEE
RGVTIDGEIVEFGSLAPDVPGLDLLTVTIGSEGMFIVVTEVTVRLIPKPQCAQLVMASFD
EEEEECCCCEECCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCHHHHHHHHHHH
DVVKGGEAVAAIIASGIIPAGLEMMDKPATQAVEAFTHAGYDLDAAAILLCESDGTQEEV
HHHCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHH
AEEIVRMTAVLREHGATRIQVSRSEAERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRA
HHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHH
IGPLLARIEQMETKYGLRCINVFHAGDGNMHPLILFNANDVDELHRAEAFGADILETCVE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHH
FGGTVTGEHGVGVEKLNSMCVQFSREECDAFFAVKRAFDPPELLNPDKGIPTRARCAEYG
HCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHC
RMHVRGGLLPHPDLPRF
CEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNAPAELSADLRAQRQREVVQALMAVLPTHCLLHRDEDTAAYECDALSAYRRLPLAVALP
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHCCEEEECC
ETESQVQRIVQICRRMNVPIVPRGAGTSLSGGALPIGHGVVLSLARFTRIVEVDSYARTA
CCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCEE
TVQPGVRNLAISEAAAPYGLYYAPDPSSQIACTIGGNVSENSGGVHCLKYGLTCHNVLRV
ECCCCHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHEE
RGVTIDGEIVEFGSLAPDVPGLDLLTVTIGSEGMFIVVTEVTVRLIPKPQCAQLVMASFD
EEEEECCCCEECCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCHHHHHHHHHHH
DVVKGGEAVAAIIASGIIPAGLEMMDKPATQAVEAFTHAGYDLDAAAILLCESDGTQEEV
HHHCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHH
AEEIVRMTAVLREHGATRIQVSRSEAERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRA
HHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHH
IGPLLARIEQMETKYGLRCINVFHAGDGNMHPLILFNANDVDELHRAEAFGADILETCVE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHH
FGGTVTGEHGVGVEKLNSMCVQFSREECDAFFAVKRAFDPPELLNPDKGIPTRARCAEYG
HCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHC
RMHVRGGLLPHPDLPRF
CEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]