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The map label for this gene is dgk [H]

Identifier: 237813674

GI number: 237813674

Start: 3333085

End: 3333774

Strand: Direct

Name: dgk [H]

Synonym: GBP346_A3451

Alternate gene names: 237813674

Gene position: 3333085-3333774 (Clockwise)

Preceding gene: 237813673

Following gene: 237813675

Centisome position: 81.32

GC content: 67.68

Gene sequence:

>690_bases
TTGCCGATGAACTCGACACCGCTTACCGTCACCGCCCCCGACTGGCGGCCGCCGTGCCGCTACCTCGCGATCGAAGGGCC
GATCGGCGTCGGCAAGACGACGCTCGCGACGCTGCTCGCCGAACGCTGGTCGATGCGCGCGCTCCTCGAGCGCCCGCAGG
ACAACCCGTTTCTCGAGCGTTTCTATCGCGACACCGCGCGCTACGCGCTGCCGACGCAGCTCGCGTTCGCGCTGCAGCGC
GAACGTCAGGCCCGCGAGATCGCCGCGGCCCACGAAGCGAACACGCCGATCGTTGCGGATTTCATGCCGCAGAAGAACGA
AATCTTCGCGCGGCTCACGCTGCCCGACGACGAATGGCAACTGTACCGCTCGCTCGCCGCGCATCTCGACGCGCCGGCGC
CCGCGCCCGATCTCGTCGTCTATCTGCAGGCGAGCCCCGAAGTGCTGTTCTCGCGCATCCAGAAACGCGGCGAGCCGATG
GAGCTGCAGATCGGCGACGCGTACCTGCGCTCGCTCTGCGACGCATACAACGAATTCTTCTATCACTACGACCGCACGCC
CGTGCTGACGGTCGCCGCCGAGCACCTGAACCCGCTCGACTCCCCCGACGACCTCGCGCTGCTCGTCGATCGCATCGCAT
CGATGCGCGGCCGCAAGGAATTCTTCGTCAAGGGCGGCAGCGCGCGCTGA

Upstream 100 bases:

>100_bases
GCCGCGCCGACGGATTCCTCGCCGACGTCGCGCACCAGCGCATCGAGAAGGTCCAGACCTGCCAGTGCCTCGCGATGCGG
GCCGCCGCCGAAAAGAACCG

Downstream 100 bases:

>100_bases
CGAACGCGCGCGGCGTCGCCGATCGCGACGCCGCCCTTTTCCTCACCATCGAATCGGACCTCCCATGACCTACCTTCAGG
AATCCAGCCGACCGGCCGTG

Product: deoxynucleoside kinase family protein

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPMNSTPLTVTAPDWRPPCRYLAIEGPIGVGKTTLATLLAERWSMRALLERPQDNPFLERFYRDTARYALPTQLAFALQR
ERQAREIAAAHEANTPIVADFMPQKNEIFARLTLPDDEWQLYRSLAAHLDAPAPAPDLVVYLQASPEVLFSRIQKRGEPM
ELQIGDAYLRSLCDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLVDRIASMRGRKEFFVKGGSAR

Sequences:

>Translated_229_residues
MPMNSTPLTVTAPDWRPPCRYLAIEGPIGVGKTTLATLLAERWSMRALLERPQDNPFLERFYRDTARYALPTQLAFALQR
ERQAREIAAAHEANTPIVADFMPQKNEIFARLTLPDDEWQLYRSLAAHLDAPAPAPDLVVYLQASPEVLFSRIQKRGEPM
ELQIGDAYLRSLCDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLVDRIASMRGRKEFFVKGGSAR
>Mature_228_residues
PMNSTPLTVTAPDWRPPCRYLAIEGPIGVGKTTLATLLAERWSMRALLERPQDNPFLERFYRDTARYALPTQLAFALQRE
RQAREIAAAHEANTPIVADFMPQKNEIFARLTLPDDEWQLYRSLAAHLDAPAPAPDLVVYLQASPEVLFSRIQKRGEPME
LQIGDAYLRSLCDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLVDRIASMRGRKEFFVKGGSAR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 26003; Mature: 25872

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMNSTPLTVTAPDWRPPCRYLAIEGPIGVGKTTLATLLAERWSMRALLERPQDNPFLER
CCCCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
FYRDTARYALPTQLAFALQRERQAREIAAAHEANTPIVADFMPQKNEIFARLTLPDDEWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCHHHH
LYRSLAAHLDAPAPAPDLVVYLQASPEVLFSRIQKRGEPMELQIGDAYLRSLCDAYNEFF
HHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
YHYDRTPVLTVAAEHLNPLDSPDDLALLVDRIASMRGRKEFFVKGGSAR
HHCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure 
PMNSTPLTVTAPDWRPPCRYLAIEGPIGVGKTTLATLLAERWSMRALLERPQDNPFLER
CCCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
FYRDTARYALPTQLAFALQRERQAREIAAAHEANTPIVADFMPQKNEIFARLTLPDDEWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCHHHH
LYRSLAAHLDAPAPAPDLVVYLQASPEVLFSRIQKRGEPMELQIGDAYLRSLCDAYNEFF
HHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
YHYDRTPVLTVAAEHLNPLDSPDDLALLVDRIASMRGRKEFFVKGGSAR
HHCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]