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The map label for this gene is tolB [H]

Identifier: 237813605

GI number: 237813605

Start: 3261833

End: 3263125

Strand: Direct

Name: tolB [H]

Synonym: GBP346_A3381

Alternate gene names: 237813605

Gene position: 3261833-3263125 (Clockwise)

Preceding gene: 237813604

Following gene: 237813606

Centisome position: 79.58

GC content: 65.12

Gene sequence:

>1293_bases
ATGACGAAGCTAGGTTTCAGGGCACTCGTGGCCTCGTGTCTGATTGCCGCGGGCGGCGCCGCCCACGCGCAGGTGAACGT
TCTGATCACGGGCGTCGGCTCCACCCAGTTTCCGATCGCCACCGCGAATTTCGTCAACGAAGCGAGCCTGCCGCAGCAGG
TCACGTCGGTCGTGCGCGGCGACCTCGCGCGAAGCGGCAAATTCTCCAACGTCGACGCGGGCAGCACGCCCGTGCCGGAA
ACCGCATCGGTCGATTTCGGCGCATGGAAGGCGAAAGGCGCGAACGCATTCGTCGCGGGCAGCGTGAACCGCGAGCCGAA
CGGCCAGTACAAGGTCAACTTCATCCTCTACGACACCGTCAAGCAGCAAAGCCTCGGAGGGCTGTCGCTCACGACGTCGA
ACGACAACGAGGGGATGCGCAAGACCGGCCACAAGATCGCCGACTACATCTACCAAAAGCTGCTCGGCGTGCGCGGCGTC
TTCAACACGCGCCTGTCGTACGTGCAGCGCACGGGCAACGTCTACAAGCTGCTGATCTCCGATTCGGACGGCCAGAACGC
GATCCCCGCGCTCACGAGCAAGGAGCCGATCATCTCGCCCGCGTGGTCGCCGAGCGGCACGAAGGTTGCGTACGTATCGT
TCGAGTTGAGAAAGCCCGTCGTGTACATCCACGATCTGCCGACCGGGCGCCGCTACGTGATCTCGAACCAGAAAGGCAAC
AACAGCGCGCCCGCGTGGTCGCCGGATGGCCAGACGCTTGCCGTCGCGCTGTCGCTCACGGGCAATACGCAGATTTACTC
CGTCAGCTCGACGGGCACCGGGCTGCGCCGCTTGACGCGCAGCAGCTCGATCGACACCGAGCCGTTCTACTCGCCTGACG
GCAAGTGGATCTATTTCACGAGCGACCGCGGCGGCGCGCCGCAAATCTACCGGATGCCCGCCGAAGGCGAGAGCGCCGGC
GCCGCTCAGCGCGTGACGTTTACCGGCAGCTACAATACGAGTCCGCGCGTCAGCCCGGACGGCAAGCTGCTCGCGTACAT
CTCACGCACGGGCGGGGGCTTCAAGCTGTACGTTCAGGATCTGCAATCGGGTGCGGCGAACGCCGTCACCAACACGACGC
GCGACGAATCGCCGAGCTTCGCGGCGAATGGTCAGTACATTCTGTACGCTACACAATCGGGGGGCCGCAGCGTGCTGGCT
GCCGTTCCGTCCGACGGCAGCGCGCCGCCGCAGATCTTGTCCGTTCAGGGCGGCGCGATCCGCGAGCCGTCCTGGGGGCC
CTTCATGCAATGA

Upstream 100 bases:

>100_bases
TTTGCGCTTACACTCCCGCCGTCGCACCGGGAACGAATCGGGTATTTTTGAGTCTCTGCGGTTGCGCAGCGTACATACGG
GAACAAGAAGCATGAGTTTG

Downstream 100 bases:

>100_bases
CCACAAGGAGAGTAACCATGATGTCGAAGAAACTTCGTCTGGCGTTCGCGATGCTGATGATCGGCGCGCTCGCGGCATGC
AAGTCGGGCGTGAAGCTCGA

Product: translocation protein TolB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTKLGFRALVASCLIAAGGAAHAQVNVLITGVGSTQFPIATANFVNEASLPQQVTSVVRGDLARSGKFSNVDAGSTPVPE
TASVDFGAWKAKGANAFVAGSVNREPNGQYKVNFILYDTVKQQSLGGLSLTTSNDNEGMRKTGHKIADYIYQKLLGVRGV
FNTRLSYVQRTGNVYKLLISDSDGQNAIPALTSKEPIISPAWSPSGTKVAYVSFELRKPVVYIHDLPTGRRYVISNQKGN
NSAPAWSPDGQTLAVALSLTGNTQIYSVSSTGTGLRRLTRSSSIDTEPFYSPDGKWIYFTSDRGGAPQIYRMPAEGESAG
AAQRVTFTGSYNTSPRVSPDGKLLAYISRTGGGFKLYVQDLQSGAANAVTNTTRDESPSFAANGQYILYATQSGGRSVLA
AVPSDGSAPPQILSVQGGAIREPSWGPFMQ

Sequences:

>Translated_430_residues
MTKLGFRALVASCLIAAGGAAHAQVNVLITGVGSTQFPIATANFVNEASLPQQVTSVVRGDLARSGKFSNVDAGSTPVPE
TASVDFGAWKAKGANAFVAGSVNREPNGQYKVNFILYDTVKQQSLGGLSLTTSNDNEGMRKTGHKIADYIYQKLLGVRGV
FNTRLSYVQRTGNVYKLLISDSDGQNAIPALTSKEPIISPAWSPSGTKVAYVSFELRKPVVYIHDLPTGRRYVISNQKGN
NSAPAWSPDGQTLAVALSLTGNTQIYSVSSTGTGLRRLTRSSSIDTEPFYSPDGKWIYFTSDRGGAPQIYRMPAEGESAG
AAQRVTFTGSYNTSPRVSPDGKLLAYISRTGGGFKLYVQDLQSGAANAVTNTTRDESPSFAANGQYILYATQSGGRSVLA
AVPSDGSAPPQILSVQGGAIREPSWGPFMQ
>Mature_429_residues
TKLGFRALVASCLIAAGGAAHAQVNVLITGVGSTQFPIATANFVNEASLPQQVTSVVRGDLARSGKFSNVDAGSTPVPET
ASVDFGAWKAKGANAFVAGSVNREPNGQYKVNFILYDTVKQQSLGGLSLTTSNDNEGMRKTGHKIADYIYQKLLGVRGVF
NTRLSYVQRTGNVYKLLISDSDGQNAIPALTSKEPIISPAWSPSGTKVAYVSFELRKPVVYIHDLPTGRRYVISNQKGNN
SAPAWSPDGQTLAVALSLTGNTQIYSVSSTGTGLRRLTRSSSIDTEPFYSPDGKWIYFTSDRGGAPQIYRMPAEGESAGA
AQRVTFTGSYNTSPRVSPDGKLLAYISRTGGGFKLYVQDLQSGAANAVTNTTRDESPSFAANGQYILYATQSGGRSVLAA
VPSDGSAPPQILSVQGGAIREPSWGPFMQ

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family [H]

Homologues:

Organism=Escherichia coli, GI1786961, Length=440, Percent_Identity=36.5909090909091, Blast_Score=247, Evalue=8e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943 [H]

Pfam domain/function: PF07676 PD40; PF04052 TolB_N [H]

EC number: NA

Molecular weight: Translated: 45562; Mature: 45431

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLGFRALVASCLIAAGGAAHAQVNVLITGVGSTQFPIATANFVNEASLPQQVTSVVRG
CCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEEHHHCCCCCCHHHHHHHHHH
DLARSGKFSNVDAGSTPVPETASVDFGAWKAKGANAFVAGSVNREPNGQYKVNFILYDTV
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCCEEEEEEEEECC
KQQSLGGLSLTTSNDNEGMRKTGHKIADYIYQKLLGVRGVFNTRLSYVQRTGNVYKLLIS
HHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEEEEEEE
DSDGQNAIPALTSKEPIISPAWSPSGTKVAYVSFELRKPVVYIHDLPTGRRYVISNQKGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCEEEEECCCCC
NSAPAWSPDGQTLAVALSLTGNTQIYSVSSTGTGLRRLTRSSSIDTEPFYSPDGKWIYFT
CCCCCCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEE
SDRGGAPQIYRMPAEGESAGAAQRVTFTGSYNTSPRVSPDGKLLAYISRTGGGFKLYVQD
CCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEEE
LQSGAANAVTNTTRDESPSFAANGQYILYATQSGGRSVLAAVPSDGSAPPQILSVQGGAI
HHCCCCHHHCCCCCCCCCCEECCCCEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCC
REPSWGPFMQ
CCCCCCCCCC
>Mature Secondary Structure 
TKLGFRALVASCLIAAGGAAHAQVNVLITGVGSTQFPIATANFVNEASLPQQVTSVVRG
CCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEEHHHCCCCCCHHHHHHHHHH
DLARSGKFSNVDAGSTPVPETASVDFGAWKAKGANAFVAGSVNREPNGQYKVNFILYDTV
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCCEEEEEEEEECC
KQQSLGGLSLTTSNDNEGMRKTGHKIADYIYQKLLGVRGVFNTRLSYVQRTGNVYKLLIS
HHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEEEEEEE
DSDGQNAIPALTSKEPIISPAWSPSGTKVAYVSFELRKPVVYIHDLPTGRRYVISNQKGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCEEEEECCCCC
NSAPAWSPDGQTLAVALSLTGNTQIYSVSSTGTGLRRLTRSSSIDTEPFYSPDGKWIYFT
CCCCCCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEE
SDRGGAPQIYRMPAEGESAGAAQRVTFTGSYNTSPRVSPDGKLLAYISRTGGGFKLYVQD
CCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEEE
LQSGAANAVTNTTRDESPSFAANGQYILYATQSGGRSVLAAVPSDGSAPPQILSVQGGAI
HHCCCCHHHCCCCCCCCCCEECCCCEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCC
REPSWGPFMQ
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA