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The map label for this gene is galE [H]

Identifier: 237813491

GI number: 237813491

Start: 3153756

End: 3154778

Strand: Direct

Name: galE [H]

Synonym: GBP346_A3267

Alternate gene names: 237813491

Gene position: 3153756-3154778 (Clockwise)

Preceding gene: 237813490

Following gene: 237813492

Centisome position: 76.95

GC content: 68.52

Gene sequence:

>1023_bases
ATGAGCACGAAGGGCACGATCCTCGTCACCGGCGGCGCGGGCTATATCGGTTCGCACACCGCCGTCGAGCTGCTCGCGCA
CGGCTACGACGTCGTGATCGCCGACAACCTCGTCAACAGCAAGCGCGAGGCGATCGCGCGGATCGAGAAGATCACCGGCA
AGACGCCGGCGTTTCACGAAACCGACGTGAGCGACGAGCGCGCGCTCGCGCGGATCTTCGACGCGCATCCGATCACGGCC
GCGATCCATTTCGCGGCGCTGAAGGCGGTCGGCGAATCGGTCGCGAAGCCCATCGAGTACTACCGCAACAACCTCGACAG
CCTGCTGTCGCTGCTGCGCGTGATGCGCGAGCGCGACGTGAAGCGGATCGTGTTCAGCTCGTCGGCGACCGTATACGGCG
TACCCGAGCGCTCGCCGATCGACGAGACGTTCCCGCTTTCGGCGACCAACCCGTACGGCCAGACGAAGCTGATGGCCGAG
CAGATCCTGCGCGATGTCGAAGCCGCCGATCCGTCCTGGCGCGTCGCGACGCTGCGCTACTTCAATCCGGTCGGCGCGCA
CGAAAGCGGCCTCATCGGCGAGGACCCGGCCGGCATTCCGAACAACCTGATGCCGTACGTCGCGCAGGTCGCGGTGGGCA
AGCTCGAGAAGCTGCGCGTGTTCGGCAGCGACTACCCGACGCCCGACGGCACCGGCGTGCGCGATTACATCCACGTCGTC
GATCTCGCGCGCGGCCACATCGCGGCGCTCGACGCGCTCGAGCGCCGCGACGCGAGCCTCACCGTCAACCTCGGCACGGG
CCGCGGCTACAGCGTGCTCGAAGTCGTGCGCGCGTTCGAGAAGGCGTCGGGGCGCGCCGTGCCGTACGAACTCGTCGCGC
GCCGCCCGGGCGACGTCGCCGAGTGCTACGCGAACCCCGCCGCGGCGGCCGAGACGATCGGATGGAAGGCCGAGCGCGAC
CTCGAGCGGATGTGCGCGGACCACTGGCGCTGGCAGGAGAACAACCCGCGCGGTTTTGTATAA

Upstream 100 bases:

>100_bases
GAAAGATCGTCGCGGAATTCGACGAGGCGAAGGTCGTCGAGCGTTATCATCAGACCATTTCGGCCCTGACGGGCATCACA
CTTTGACGGAGCAATCAGCA

Downstream 100 bases:

>100_bases
TCCGCTGTCCAATTTTCGGGCACGCCCATGCTCAGCTTCGCCGTCGGCTTCATCGTCTCGCTTCTCGTCACGCTGCTCAT
CGTCCGCTATGCGCACCTGC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSTKGTILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSDERALARIFDAHPITA
AIHFAALKAVGESVAKPIEYYRNNLDSLLSLLRVMRERDVKRIVFSSSATVYGVPERSPIDETFPLSATNPYGQTKLMAE
QILRDVEAADPSWRVATLRYFNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
DLARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAFEKASGRAVPYELVARRPGDVAECYANPAAAAETIGWKAERD
LERMCADHWRWQENNPRGFV

Sequences:

>Translated_340_residues
MSTKGTILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSDERALARIFDAHPITA
AIHFAALKAVGESVAKPIEYYRNNLDSLLSLLRVMRERDVKRIVFSSSATVYGVPERSPIDETFPLSATNPYGQTKLMAE
QILRDVEAADPSWRVATLRYFNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
DLARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAFEKASGRAVPYELVARRPGDVAECYANPAAAAETIGWKAERD
LERMCADHWRWQENNPRGFV
>Mature_339_residues
STKGTILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSDERALARIFDAHPITAA
IHFAALKAVGESVAKPIEYYRNNLDSLLSLLRVMRERDVKRIVFSSSATVYGVPERSPIDETFPLSATNPYGQTKLMAEQ
ILRDVEAADPSWRVATLRYFNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVVD
LARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAFEKASGRAVPYELVARRPGDVAECYANPAAAAETIGWKAERDL
ERMCADHWRWQENNPRGFV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=57.9411764705882, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=57.9411764705882, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=57.9411764705882, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=25.1824817518248, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=53.8922155688623, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=25.6906077348066, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994969, Length=344, Percent_Identity=24.1279069767442, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=54.8104956268222, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=54.4927536231884, Blast_Score=381, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6319493, Length=347, Percent_Identity=52.7377521613833, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=54.8104956268222, Blast_Score=391, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37183; Mature: 37052

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKGTILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHE
CCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCC
TDVSDERALARIFDAHPITAAIHFAALKAVGESVAKPIEYYRNNLDSLLSLLRVMRERDV
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
KRIVFSSSATVYGVPERSPIDETFPLSATNPYGQTKLMAEQILRDVEAADPSWRVATLRY
HHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEE
FNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
DLARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAFEKASGRAVPYELVARRPGDVA
HHHCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHH
ECYANPAAAAETIGWKAERDLERMCADHWRWQENNPRGFV
HHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
STKGTILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHE
CCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCC
TDVSDERALARIFDAHPITAAIHFAALKAVGESVAKPIEYYRNNLDSLLSLLRVMRERDV
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
KRIVFSSSATVYGVPERSPIDETFPLSATNPYGQTKLMAEQILRDVEAADPSWRVATLRY
HHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEE
FNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
DLARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAFEKASGRAVPYELVARRPGDVA
HHHCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHH
ECYANPAAAAETIGWKAERDLERMCADHWRWQENNPRGFV
HHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]