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The map label for this gene is ureC [H]

Identifier: 237813480

GI number: 237813480

Start: 3141379

End: 3143085

Strand: Direct

Name: ureC [H]

Synonym: GBP346_A3256

Alternate gene names: 237813480

Gene position: 3141379-3143085 (Clockwise)

Preceding gene: 237813479

Following gene: 237813481

Centisome position: 76.65

GC content: 68.31

Gene sequence:

>1707_bases
ATGACATTACGTTTGAGCCGCCGCGCGTACGCGGAAATGTACGGGCCGACGACGGGCGACCGCATCCGCCTCGCGGACAC
CGAACTGCTGATCGAAGTCGAGCGCGACCACACGCTCTACGGCGAGGAAGTGAAGTTCGGCGGCGGCAAGGTGATCCGCG
ACGGCATGGGCCAATCGCAGCTCCCCGCGGCCGACGTGGCGGACACCGTGATCACGAACGCGGTGATTCTCGATCACTGG
GGCATCGTGAAGGCGGACATCGCGATCAAGCACGGCCGCATCGCGGCGATCGGCAAGGCGGGCAATCCGGACATCCAGCC
GGGCGTGACGATCGCGATCGGCGCGGCGACCGAGATCATCGCGGGCGAAGGCCTGATCGTGACGGCGGGCGGCATCGATA
CGCACATCCACTTCATCAGCCCGCAGCAGATCGACGAAGCGCTCGCATCGGGCGTGACGACGATGATCGGCGGCGGCACG
GGCCCTGCGACCGGCACCAACGCGACGACCTGCACGCCGGGGCCGTGGCACATGGAGCGGATGCTGCAGGCGGCCGACGG
CTGGCCGATCAATCTCGGCTTTCTCGGCAAGGGCAACGCGAGCCGGCCGCAGCCGCTCGTCGAGCAGATCGAGGCGGGCG
CGATCGGCCTGAAGCTGCACGAGGACTGGGGCACGACGCCCGCCGCGATCGACAACTGCCTGACGGTGGCCGACGACACC
GACACGCAGGTCGCGATTCACACCGATACGCTGAACGAGGCCGGCTTCGTCGAGGCGACGGTCGCCGCGTTCAAGGGCCG
CACGATCCACACGTACCACACCGAGGGCGCGGGCGGCGGCCATGCGCCCGACATCCTGAAGGTGTGCGGCGAGGCGAACG
TGCTGCCTTCATCGACGAACCCGACGCGCCCGTACACGATCAACACGCTCGACGAACACCTCGACATGCTGATGGTCTGC
CATCACCTCGATCCGTCGATCGCCGAGGATCTCGCGTTCGCCGAATCGCGGATTCGCCGCGAGACGATCGCGGCCGAGGA
CATCCTGCACGACCTCGGCGCGCTGTCGATGCTGTCGTCCGATTCGCAGGCGATGGGCCGCGTCGGCGAAGTGATCATCC
GCACGTGGCAGACCGCGCACAAGATGAAGGTGCAGCGCGGCGCGCTCGCCGACGACGGCGCGCGCAACGACAACTTCCGC
GCGAAGCGCTACGTCGCGAAATACACGATCAATCCGGCGCTCACGCACGGCATCGCGCACGAGGTCGGCTCGATCGAGCC
GGGCAAATGGGCGGACCTCGTGCTGTGGGAGCCCGCGTTCTTCGGGGTCAAGCCGGCGATGATCGTCAAGGGCGGCATGA
TCGCCGTCGCGCAGATGGGCGATCCGAATGCGTCGATCCCGACGCCGCAGCCCGTGCATTACCGCGAGATGTTCGCCACC
CGCGGCGGCGCGCTCGCGCGCACGTCGCTCACGTTCGTGTCGCAGCTCGCGCTCGATGCGGGCATCGGCGCGCGCTACGG
GCTCGCGAAGCGGCTCGTGCCGGTGCGCGGCTGCCGCACGGTGACCAAGCGCGACATGATCCACAACGCATGGCAACCGG
CCATCCGCGTCGACCCCGAAACCTACGACGTCGTCGCCGACGGCGCGCTGCTCACCTGCGAGCCCGCCGCCGTGCTGCCG
ATGGCGCAACGCTACTTCCTGTTCTGA

Upstream 100 bases:

>100_bases
TACGGCTTCCAGGGCAAGGTGATGGGGCCGCTCTGAGCGCCGGCGCTTCGCCGCGCTGCGCTGTGACACGCCCGCACGGG
CATCCGAAGGATTCGACGAC

Downstream 100 bases:

>100_bases
AGCCCTGACGAATCATCATGCGCACGATCGACAAACGCATCGCCCCGAACGTGAGGCTCGCCGCCACGCTCGTCGCGCGC
GCGCCCGCGCTCACGCTCGC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MTLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQLPAADVADTVITNAVILDHW
GIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGT
GPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDT
DTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTNPTRPYTINTLDEHLDMLMVC
HHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALADDGARNDNFR
AKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIVKGGMIAVAQMGDPNASIPTPQPVHYREMFAT
RGGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPETYDVVADGALLTCEPAAVLP
MAQRYFLF

Sequences:

>Translated_568_residues
MTLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQLPAADVADTVITNAVILDHW
GIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGT
GPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDT
DTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTNPTRPYTINTLDEHLDMLMVC
HHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALADDGARNDNFR
AKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIVKGGMIAVAQMGDPNASIPTPQPVHYREMFAT
RGGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPETYDVVADGALLTCEPAAVLP
MAQRYFLF
>Mature_567_residues
TLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQLPAADVADTVITNAVILDHWG
IVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTG
PATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDTD
TQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTNPTRPYTINTLDEHLDMLMVCH
HLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALADDGARNDNFRA
KRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIVKGGMIAVAQMGDPNASIPTPQPVHYREMFATR
GGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPETYDVVADGALLTCEPAAVLPM
AQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 60721; Mature: 60590

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQ
CEEEECHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCCCCEEEECCCEEEECCCCCCC
LPAADVADTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEII
CCHHHHHHHHHHHEEEEECCCEEEEEEEEECCCEEEECCCCCCCCCCCEEEEECCCEEEE
AGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTGPATGTNATTCTPGPWHMER
ECCCEEEEECCCEEEEEEECHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHHHHH
MLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDT
HHHHCCCCEEEEEEECCCCCCCCCHHHHHHCCCEEEEEEECCCCCCHHHHHCEEEEECCC
DTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTN
CCEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCC
PTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSS
CCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSQAMGRVGEVIIRTWQTAHKMKVQRGALADDGARNDNFRAKRYVAKYTINPALTHGIAH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEEECCHHHHHHHHH
EVGSIEPGKWADLVLWEPAFFGVKPAMIVKGGMIAVAQMGDPNASIPTPQPVHYREMFAT
HHCCCCCCCCEEEEEECCHHHCCCCHHEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
RGGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPE
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECCC
TYDVVADGALLTCEPAAVLPMAQRYFLF
CEEEEECCEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
TLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQ
EEEECHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCCCCEEEECCCEEEECCCCCCC
LPAADVADTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEII
CCHHHHHHHHHHHEEEEECCCEEEEEEEEECCCEEEECCCCCCCCCCCEEEEECCCEEEE
AGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTGPATGTNATTCTPGPWHMER
ECCCEEEEECCCEEEEEEECHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHHHHH
MLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDT
HHHHCCCCEEEEEEECCCCCCCCCHHHHHHCCCEEEEEEECCCCCCHHHHHCEEEEECCC
DTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTN
CCEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCC
PTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSS
CCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSQAMGRVGEVIIRTWQTAHKMKVQRGALADDGARNDNFRAKRYVAKYTINPALTHGIAH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEEECCHHHHHHHHH
EVGSIEPGKWADLVLWEPAFFGVKPAMIVKGGMIAVAQMGDPNASIPTPQPVHYREMFAT
HHCCCCCCCCEEEEEECCHHHCCCCHHEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
RGGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPE
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECCC
TYDVVADGALLTCEPAAVLPMAQRYFLF
CEEEEECCEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA