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The map label for this gene is tdcB [H]

Identifier: 237813439

GI number: 237813439

Start: 3109155

End: 3110138

Strand: Reverse

Name: tdcB [H]

Synonym: GBP346_A3214

Alternate gene names: 237813439

Gene position: 3110138-3109155 (Counterclockwise)

Preceding gene: 237813441

Following gene: 237813436

Centisome position: 75.88

GC content: 70.73

Gene sequence:

>984_bases
ATGTCCGTTCAATCCGCCTCCGACCTTATTTTGCCGACCTTCGACGACGTGACCGACGCAGCCGCCCGGCTCGCCGGCGT
CGCGCATCGCACGCCCGTCCTCACGTCGAGCACCGCCGACGCGCGCGCGGGCGCGACGATCTTCTTCAAATGCGAGAACT
TCCAGCGGATGGGCGCGTTCAAGTTTCGCGGCGCATACAACGCGATTTCGCACTTCGACGCCGAGCAGCGCCGCGCGGGC
GTGCTCACGTATTCGTCGGGCAACCATGCGCAGGCGATCGCGCTCGCCGCGCGTCTCGCGGGCATCCGCGCGACGATCGT
GATGCCGCACGACGCGCCGGCCGCGAAGGTCGCGGCGACGAAGGGCTACGGCGGCGAAGTCATCACCTACGATCGCTACA
CGGAAAGCCGGGAGGAGATCGGCGCGCGGCTCGCGCAGGAGCGCGGCATGACGCTCGTGCCGCCGTACGATCACCCGCAC
GTGATCGCCGGCCAGGGGACGGCCGCGAAAGAGCTGATCGACGAAGTCGGCGAGCTCGACATGCTCGTCGCGCCGCTCGG
CGGCGGCGGGCTGATCGCGGGCACCGCGCTGTCGGCCGCCGCGCTGTCGGCGGGCTGCGCGGTGATCGGCGTCGAGCCGG
AGGCGGGCAACGACGCGCAGCAGTCGCTCGAGCGCGGCGAGGTCGTGCGCATTCCGGTGCCGCGGACGATCGCGGACGGC
GCGGCGTCGACGCACGTCGGCGCGTACAACTTTCCGGTCATCCAGCGGCTCGTCAAGCGGATCGTCACGGCGAGCGACGC
GCAGCTCGTCGATACGATGCGTTTTTTCGCGGAGCGGATGAAACTCGTCGTCGAGCCGACCGGCTGCCTCGGCGCGGCCG
CGGTGCTTGACGGCGTGCTGCCCGTCGCGGGCAGGCGCATCGGCGTGATCCTGAGCGGCGGCAACGTCGATCTCGCGCGC
TACGGCGAGTTCCTGCGCGGGTGA

Upstream 100 bases:

>100_bases
TGTCCGTGCCGCGCCGTTTTCTTTTCAGGTGGCTGCGCGCGGCGCGCGAAGCTGGGACAATGGCCCCTTCCTTGTCCAAC
GCGTTTTCGCACTCGCCGCC

Downstream 100 bases:

>100_bases
GCATGGCGGCCGGCCGCTTGCGCGGCCGTCGCAGCCCGCCTGCGCGTGCGGCACGGAGCCGGCCGGCACCGGCGAGTGCC
GCCGACGTGTGCGGCCGTCG

Product: serine/threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSVQSASDLILPTFDDVTDAAARLAGVAHRTPVLTSSTADARAGATIFFKCENFQRMGAFKFRGAYNAISHFDAEQRRAG
VLTYSSGNHAQAIALAARLAGIRATIVMPHDAPAAKVAATKGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPH
VIAGQGTAAKELIDEVGELDMLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVRIPVPRTIADG
AASTHVGAYNFPVIQRLVKRIVTASDAQLVDTMRFFAERMKLVVEPTGCLGAAAVLDGVLPVAGRRIGVILSGGNVDLAR
YGEFLRG

Sequences:

>Translated_327_residues
MSVQSASDLILPTFDDVTDAAARLAGVAHRTPVLTSSTADARAGATIFFKCENFQRMGAFKFRGAYNAISHFDAEQRRAG
VLTYSSGNHAQAIALAARLAGIRATIVMPHDAPAAKVAATKGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPH
VIAGQGTAAKELIDEVGELDMLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVRIPVPRTIADG
AASTHVGAYNFPVIQRLVKRIVTASDAQLVDTMRFFAERMKLVVEPTGCLGAAAVLDGVLPVAGRRIGVILSGGNVDLAR
YGEFLRG
>Mature_326_residues
SVQSASDLILPTFDDVTDAAARLAGVAHRTPVLTSSTADARAGATIFFKCENFQRMGAFKFRGAYNAISHFDAEQRRAGV
LTYSSGNHAQAIALAARLAGIRATIVMPHDAPAAKVAATKGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPHV
IAGQGTAAKELIDEVGELDMLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVRIPVPRTIADGA
ASTHVGAYNFPVIQRLVKRIVTASDAQLVDTMRFFAERMKLVVEPTGCLGAAAVLDGVLPVAGRRIGVILSGGNVDLARY
GEFLRG

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=321, Percent_Identity=40.4984423676012, Blast_Score=232, Evalue=3e-61,
Organism=Homo sapiens, GI19923959, Length=300, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI295821202, Length=181, Percent_Identity=33.1491712707182, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI295821200, Length=181, Percent_Identity=33.1491712707182, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4557415, Length=181, Percent_Identity=33.1491712707182, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI33469958, Length=307, Percent_Identity=28.3387622149837, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789505, Length=318, Percent_Identity=36.7924528301887, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1790207, Length=293, Percent_Identity=35.8361774744027, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17508781, Length=311, Percent_Identity=33.7620578778135, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71991565, Length=310, Percent_Identity=32.258064516129, Blast_Score=147, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17537387, Length=313, Percent_Identity=32.2683706070287, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322631, Length=319, Percent_Identity=58.9341692789969, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6320930, Length=304, Percent_Identity=34.8684210526316, Blast_Score=156, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6319788, Length=286, Percent_Identity=23.4265734265734, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355833, Length=314, Percent_Identity=36.624203821656, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24645328, Length=219, Percent_Identity=35.6164383561644, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 34169; Mature: 34038

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQSASDLILPTFDDVTDAAARLAGVAHRTPVLTSSTADARAGATIFFKCENFQRMGAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCHHCCCE
KFRGAYNAISHFDAEQRRAGVLTYSSGNHAQAIALAARLAGIRATIVMPHDAPAAKVAAT
EECCHHHHHHHCCHHHHHCCEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHEEEE
KGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPHVIAGQGTAAKELIDEVGELD
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCHHHHHHHHHCCCE
MLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVRIPVPRTIADG
EEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCEEEECCCCHHCCC
AASTHVGAYNFPVIQRLVKRIVTASDAQLVDTMRFFAERMKLVVEPTGCLGAAAVLDGVL
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
PVAGRRIGVILSGGNVDLARYGEFLRG
HHCCCEEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
SVQSASDLILPTFDDVTDAAARLAGVAHRTPVLTSSTADARAGATIFFKCENFQRMGAF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCHHCCCE
KFRGAYNAISHFDAEQRRAGVLTYSSGNHAQAIALAARLAGIRATIVMPHDAPAAKVAAT
EECCHHHHHHHCCHHHHHCCEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHEEEE
KGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPHVIAGQGTAAKELIDEVGELD
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCHHHHHHHHHCCCE
MLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVRIPVPRTIADG
EEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCEEEECCCCHHCCC
AASTHVGAYNFPVIQRLVKRIVTASDAQLVDTMRFFAERMKLVVEPTGCLGAAAVLDGVL
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
PVAGRRIGVILSGGNVDLARYGEFLRG
HHCCCEEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA