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The map label for this gene is yfdZ [C]

Identifier: 237813434

GI number: 237813434

Start: 3102929

End: 3104122

Strand: Direct

Name: yfdZ [C]

Synonym: GBP346_A3209

Alternate gene names: 237813434

Gene position: 3102929-3104122 (Clockwise)

Preceding gene: 237813433

Following gene: 237813435

Centisome position: 75.71

GC content: 69.43

Gene sequence:

>1194_bases
ATGAATACCGCTGCCGATTCGCTCCTGAGGCTCGCGTCGCGCGTCGACGCGATCGAGCCGTTCTACGTGATGGAAATCGT
CAAGGAAGCCGCCGTGCTCGAGCGCGCCGGCCGCGACATCATCCATATGAGCATCGGCGAGCCGGATTTCACGGCGCCCG
AGCCCGTCGTCGACGCGGCCGCCGCCGCGCTGCGCCGAGGCGTCACGCAATACACGAGCGCGCTCGGCATCGCGCCGCTG
CGCGAGGCGATCGCCGCGCACTATGCGCGCGCGCACGGGCTCTCGATCGCACCCGAGCGGATTGTCGTGACGGCGGGCGC
ATCGGCCGCGCTGCTGCTCGCGTGCCTCGCGCTCGTCGGCCGCGACGACGAAGTGCTGATGCCCGACCCGTCGTATCCGT
GCAACCGCCACTTCGTCGCGACGGCCGAAGGCCGCGCAGTGCTCGTGCCGAGCGGCCCCGAAACCCGCTTCCAGCTGACC
GCGGACGACGTGAAAACGCGCTGGGGCGAGCGCACGCGCGGCGTGCTGCTCGCGTCGCCGTCGAACCCGACGGGCACGTC
GCTCGAGCCCGCCGAGCTCGGTCGGATCATCGGCGCCGTTCGCGCACGCGGCGGCTTTTCGATCGTCGACGAGATTTACC
AGGGGCTGAGCTACGACGGCGCGCCCGTGTCGGCGCTGTCGTTCGGCGACGACGTCGTCACCGTCAACAGCTTCTCGAAA
TACTTCAACATGACCGGCTGGCGGCTCGGCTGGCTCGTCGTGCCGCCGGCGCTCGTCGGCACGTTCGAGAAGCTCGCGCA
GAACCTGTTCATCTGCCCGTCCGCCCTCGCGCAGCATGCGGCGCTCGCGTGCTTCGAGCCGGACACCCTCGCGATCTACG
AGGCGCGCCGCGCCGAATTCCGGCGTCGCCGCGATTTCATCGTGCCGGCGATCGAATCGCTCGGCTTCAAGGTGCCCGTG
ATGCCCGACGGCGCGTTCTATGTGTACGCGCAATGCGGCGGCGTCGCGCATCCGGCCGCAGGAGACAGCGCCGCGCTCGT
GAACGCGATGCTGCACGACGCGGGCGTCGTGCTCGTGCCGGGGATGGATTTCGGAGTTCATGCGCCGCGCGACTATATCC
GCCTGTCCTATGCAACCGCGTACTCGCGGCTCGAAGAGGCGGTCGAGCGTCTCGGCAAGCTGTTCGGGCGCTAA

Upstream 100 bases:

>100_bases
CGCCCGGCCGAGACGCAAGCGCGGCGCGGCGCGTAACCTTCCTTTGCGGGCGCGCAGCGCGCGCCCGCTTTTCGCCTTCC
TCCCCCGTTTTGATTCGACG

Downstream 100 bases:

>100_bases
CCGCCGCATGCGGACGGCCGCCGGCGCGGCGTTCGGCAAAGCGCTGGGGGCCGACGGCCGGTGCCGCCGGCTCGCTCGCC
ACGCGGCCCCCCTCCGCCTG

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNTAADSLLRLASRVDAIEPFYVMEIVKEAAVLERAGRDIIHMSIGEPDFTAPEPVVDAAAAALRRGVTQYTSALGIAPL
REAIAAHYARAHGLSIAPERIVVTAGASAALLLACLALVGRDDEVLMPDPSYPCNRHFVATAEGRAVLVPSGPETRFQLT
ADDVKTRWGERTRGVLLASPSNPTGTSLEPAELGRIIGAVRARGGFSIVDEIYQGLSYDGAPVSALSFGDDVVTVNSFSK
YFNMTGWRLGWLVVPPALVGTFEKLAQNLFICPSALAQHAALACFEPDTLAIYEARRAEFRRRRDFIVPAIESLGFKVPV
MPDGAFYVYAQCGGVAHPAAGDSAALVNAMLHDAGVVLVPGMDFGVHAPRDYIRLSYATAYSRLEEAVERLGKLFGR

Sequences:

>Translated_397_residues
MNTAADSLLRLASRVDAIEPFYVMEIVKEAAVLERAGRDIIHMSIGEPDFTAPEPVVDAAAAALRRGVTQYTSALGIAPL
REAIAAHYARAHGLSIAPERIVVTAGASAALLLACLALVGRDDEVLMPDPSYPCNRHFVATAEGRAVLVPSGPETRFQLT
ADDVKTRWGERTRGVLLASPSNPTGTSLEPAELGRIIGAVRARGGFSIVDEIYQGLSYDGAPVSALSFGDDVVTVNSFSK
YFNMTGWRLGWLVVPPALVGTFEKLAQNLFICPSALAQHAALACFEPDTLAIYEARRAEFRRRRDFIVPAIESLGFKVPV
MPDGAFYVYAQCGGVAHPAAGDSAALVNAMLHDAGVVLVPGMDFGVHAPRDYIRLSYATAYSRLEEAVERLGKLFGR
>Mature_397_residues
MNTAADSLLRLASRVDAIEPFYVMEIVKEAAVLERAGRDIIHMSIGEPDFTAPEPVVDAAAAALRRGVTQYTSALGIAPL
REAIAAHYARAHGLSIAPERIVVTAGASAALLLACLALVGRDDEVLMPDPSYPCNRHFVATAEGRAVLVPSGPETRFQLT
ADDVKTRWGERTRGVLLASPSNPTGTSLEPAELGRIIGAVRARGGFSIVDEIYQGLSYDGAPVSALSFGDDVVTVNSFSK
YFNMTGWRLGWLVVPPALVGTFEKLAQNLFICPSALAQHAALACFEPDTLAIYEARRAEFRRRRDFIVPAIESLGFKVPV
MPDGAFYVYAQCGGVAHPAAGDSAALVNAMLHDAGVVLVPGMDFGVHAPRDYIRLSYATAYSRLEEAVERLGKLFGR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=418, Percent_Identity=27.0334928229665, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI169881279, Length=418, Percent_Identity=27.0334928229665, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI56713254, Length=353, Percent_Identity=26.0623229461756, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI56713256, Length=340, Percent_Identity=26.1764705882353, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=24.1721854304636, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=22.9381443298969, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=28.7878787878788, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786816, Length=374, Percent_Identity=29.144385026738, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=26.4248704663212, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1787710, Length=335, Percent_Identity=25.6716417910448, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=391, Percent_Identity=25.8312020460358, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=391, Percent_Identity=25.8312020460358, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=319, Percent_Identity=25.0783699059561, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17567663, Length=398, Percent_Identity=25.1256281407035, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=23.6503856041131, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=25.9640102827763, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=25.9640102827763, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=25.9640102827763, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=25.9640102827763, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI18859735, Length=399, Percent_Identity=24.3107769423559, Blast_Score=98, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42557; Mature: 42557

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAADSLLRLASRVDAIEPFYVMEIVKEAAVLERAGRDIIHMSIGEPDFTAPEPVVDAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHH
AAALRRGVTQYTSALGIAPLREAIAAHYARAHGLSIAPERIVVTAGASAALLLACLALVG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHC
RDDEVLMPDPSYPCNRHFVATAEGRAVLVPSGPETRFQLTADDVKTRWGERTRGVLLASP
CCCCEECCCCCCCCCCCEEEECCCCEEEECCCCCCEEEEEHHHHHHHCCCCCCCEEEECC
SNPTGTSLEPAELGRIIGAVRARGGFSIVDEIYQGLSYDGAPVSALSFGDDVVTVNSFSK
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEHHHHHH
YFNMTGWRLGWLVVPPALVGTFEKLAQNLFICPSALAQHAALACFEPDTLAIYEARRAEF
HHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCEEEHHHHHHHH
RRRRDFIVPAIESLGFKVPVMPDGAFYVYAQCGGVAHPAAGDSAALVNAMLHDAGVVLVP
HHHHCHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEC
GMDFGVHAPRDYIRLSYATAYSRLEEAVERLGKLFGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTAADSLLRLASRVDAIEPFYVMEIVKEAAVLERAGRDIIHMSIGEPDFTAPEPVVDAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHH
AAALRRGVTQYTSALGIAPLREAIAAHYARAHGLSIAPERIVVTAGASAALLLACLALVG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHC
RDDEVLMPDPSYPCNRHFVATAEGRAVLVPSGPETRFQLTADDVKTRWGERTRGVLLASP
CCCCEECCCCCCCCCCCEEEECCCCEEEECCCCCCEEEEEHHHHHHHCCCCCCCEEEECC
SNPTGTSLEPAELGRIIGAVRARGGFSIVDEIYQGLSYDGAPVSALSFGDDVVTVNSFSK
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEHHHHHH
YFNMTGWRLGWLVVPPALVGTFEKLAQNLFICPSALAQHAALACFEPDTLAIYEARRAEF
HHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCEEEHHHHHHHH
RRRRDFIVPAIESLGFKVPVMPDGAFYVYAQCGGVAHPAAGDSAALVNAMLHDAGVVLVP
HHHHCHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEC
GMDFGVHAPRDYIRLSYATAYSRLEEAVERLGKLFGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]