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The map label for this gene is ribE [H]

Identifier: 237813428

GI number: 237813428

Start: 3099616

End: 3100230

Strand: Direct

Name: ribE [H]

Synonym: GBP346_A3203

Alternate gene names: 237813428

Gene position: 3099616-3100230 (Clockwise)

Preceding gene: 237813427

Following gene: 237813430

Centisome position: 75.63

GC content: 67.32

Gene sequence:

>615_bases
ATGTTTACCGGAATCGTCGCGGCGGTCGGCCGCATCGAAGCGATCACGCCGATCGCCGCCTCGCCCGATGCGGGCGTGCG
CCTCACGCTGCGCGCAGGCGGGCTCGACCTCGCCGATGTCGCGCTCGGCGACAGCATCGCGATCCAGGGCGCGTGCATGA
CGGTCGTCGCGAAGACGGCCGACACGTTCGACGTCGAGGTGTCGCGCGAAAGCCTGAACAGGACGGTCGGCCTCGCCGAG
CCGGGCGACGTGAATCTTGAAAAGGCGCTGCGCGCGCACGACCGGCTGGGCGGCCACATCGTGTCCGGGCACGTCGACGG
GCTCGGCACCGTCACGCGCTTCGCGCCCGTGGGCGAATCGCACGAACTGCGCGTGCTCGCGCCGCGCGAGCTCGGCCGCT
ATCTCGCGTACAAGGGCTCGATCACCGTCAACGGCGTGAGCCTCACCGTCAATTCGGTCGACGACCGCGACGACGGCTGC
GAATTCTCGATCAACCTGATTCCTCATACGGTCGAAGTGACGACGCTGCGGCACCTGACGGCCGGCGCGAAGGTCAATCT
CGAGATCGACATGATCGCGCGGTATGTGGAGCGGATGACGAACGCACCGAAATAA

Upstream 100 bases:

>100_bases
ACAGCGTCGAGCGCGTCGGCGACGACCTGCGCATTCTCGCGCGCTTCGCGAACGCTCACGCGAGCGCCTCCCCTACTCGT
TCATAACGGAATCCGACACG

Downstream 100 bases:

>100_bases
GCGCGCATCGGCGCCGCGCGCGTCGTGCTTGGGCTCGTGCGGCCGGAATTGCCGCCGTGCGACGCGCGTTCGTTCGATCG
GCCCGGCCGCCGGGCGAGCG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MFTGIVAAVGRIEAITPIAASPDAGVRLTLRAGGLDLADVALGDSIAIQGACMTVVAKTADTFDVEVSRESLNRTVGLAE
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGESHELRVLAPRELGRYLAYKGSITVNGVSLTVNSVDDRDDGC
EFSINLIPHTVEVTTLRHLTAGAKVNLEIDMIARYVERMTNAPK

Sequences:

>Translated_204_residues
MFTGIVAAVGRIEAITPIAASPDAGVRLTLRAGGLDLADVALGDSIAIQGACMTVVAKTADTFDVEVSRESLNRTVGLAE
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGESHELRVLAPRELGRYLAYKGSITVNGVSLTVNSVDDRDDGC
EFSINLIPHTVEVTTLRHLTAGAKVNLEIDMIARYVERMTNAPK
>Mature_204_residues
MFTGIVAAVGRIEAITPIAASPDAGVRLTLRAGGLDLADVALGDSIAIQGACMTVVAKTADTFDVEVSRESLNRTVGLAE
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGESHELRVLAPRELGRYLAYKGSITVNGVSLTVNSVDDRDDGC
EFSINLIPHTVEVTTLRHLTAGAKVNLEIDMIARYVERMTNAPK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=198, Percent_Identity=32.8282828282828, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319733, Length=207, Percent_Identity=34.7826086956522, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21567; Mature: 21567

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVAAVGRIEAITPIAASPDAGVRLTLRAGGLDLADVALGDSIAIQGACMTVVAKTA
CCCHHHHHHHCHHEECCCCCCCCCCEEEEEEECCCCEEHEECCCCEEECCCEEEEEEECC
DTFDVEVSRESLNRTVGLAEPGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGES
CCEEEEEEHHHHCCEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCCCC
HELRVLAPRELGRYLAYKGSITVNGVSLTVNSVDDRDDGCEFSINLIPHTVEVTTLRHLT
CCEEEECHHHHCCCEEEECCEEEEEEEEEEECCCCCCCCCEEEEEECCCEEEEEEEEECC
AGAKVNLEIDMIARYVERMTNAPK
CCCEEEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIVAAVGRIEAITPIAASPDAGVRLTLRAGGLDLADVALGDSIAIQGACMTVVAKTA
CCCHHHHHHHCHHEECCCCCCCCCCEEEEEEECCCCEEHEECCCCEEECCCEEEEEEECC
DTFDVEVSRESLNRTVGLAEPGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGES
CCEEEEEEHHHHCCEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCCCC
HELRVLAPRELGRYLAYKGSITVNGVSLTVNSVDDRDDGCEFSINLIPHTVEVTTLRHLT
CCEEEECHHHHCCCEEEECCEEEEEEEEEEECCCCCCCCCEEEEEECCCEEEEEEEEECC
AGAKVNLEIDMIARYVERMTNAPK
CCCEEEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]