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The map label for this gene is ftsK2 [H]

Identifier: 237813406

GI number: 237813406

Start: 3075379

End: 3077847

Strand: Reverse

Name: ftsK2 [H]

Synonym: GBP346_A3181

Alternate gene names: 237813406

Gene position: 3077847-3075379 (Counterclockwise)

Preceding gene: 237813410

Following gene: 237813405

Centisome position: 75.1

GC content: 67.64

Gene sequence:

>2469_bases
GTGGCGGCGCGCGCACATTTCGGCCCGAGTCGGCCGGGCGTTACCGTCATTTACACTTGGCGCGGCGGCGCAGCGTTTAC
AATAGATCGGATCGAACGATCGGCGGGCTGTCGGCGGTTTTTTGCCGCACGCGGCCGCCTCATCGCCCCTTTTGACGGAT
TCATGGCAAAAGCACCTTATACCGCTCAGGCCCAGGCGCTACCGCACCGGATGTCGCGCCTACTGACCGAGATCCGCTGG
ATTCTCCAGGTCGCGCTGCTCGCCTTCCTGCTGATGGCGCTCCTGAGCTACAGCCGGCGCGATCCGAGCTGGACCCACGC
CGCGCAGGTCGACCACATCGCGAACTGGGCAGGGCGGGTCGGCGCATGGACGGCCGACATCATGCTGCTGCTCTTCGGCC
TGTCCGCGTACTGGCTCATCGTGCTGCTCGGCCGGCGCGTGGCCGCGAACTATCGTCGCATCACCCGGCACGACGCGCTG
CCCGGCGAGCCGGAGAAGCCGGCCGGCTGGCTCGCCGAAGGCTTCGCGTTCGTGCTCGTGCTGCTCGCGAGCGACGGCAT
CGAGGCGCTGCGGATGTGGTCGCTGAAAGTGCAGTTGCCGCGCGCGCCGGGCGGCGTCGTCGGCGAGACGGTCGCGCGCG
GCGTCGCGCACGCGCTCGGCTTCACGGGCGGCACGCTCGCGCTGCTGATCGCGCTCGCGATCGGGCTGTCGCTGTATTTC
CGCTTTTCGTGGCTGTCGGTCGCCGAACGCGTCGGCGACGCGATCATCAACGCGTTCACGCTCGCGAAGCTGCGCCGCGA
GGCCGAGCGCGACCGCAAGCTCGGCGAGGCCGCGGCCGTCAAGCGCGAGGGCAAGGTGGAGGAGGAGCGCGTGCGCATCG
AGGAGCACGAGCCCGTCACGATCGTGCCGCCCGTCGTCACGCCCGCCAAATCCGAGCGCGCCGAGAAGGAGCGCCAGCAG
CCGCTGTTCACCGATCTGCCGGGCGATTCGACGCTGCCCGCGATCGCGCTGCTCGACCCCGCGCCGACGTCGCAGGAGAC
GATCTCCGCGGACACGCTCGAATTCACCTCGCGCCTGATCGAGAAGAAGCTGAAGGATTTCGGCGTCGAGGTGAGCGTCG
TCGCCGCGTATCCGGGCCCCGTCGTCACCCGCTACGAGATCGAGCCGGCGACGGGCGTGAAGGGCAGCCAGATCGTCAAT
CTGTCGAAGGATCTCGCGCGCTCGCTGTCGCTCGTGTCGATCCGCGTCGTCGAGACGATTCCCGGCAAGAACTTCATGGC
GCTCGAATTGCCGAACCAGCGCCGCCAGACGGTGCGGCTGTCCGAGATCCTCGGCTCCGAGGTCTATGCGGACGCGCCGT
CGATGCTCACCCTCGGCCTCGGCAAGGACATCGGCGGCAAGCCGGTGTGCGCGGATCTCGCGAAGATGCCGCACTTGCTC
GTCGCCGGCACGACGGGCTCGGGCAAGTCGGTGGGGATCAACGCGATGATCCTGTCGCTGCTCTACAAGGCGAGCGCCGA
GCAGGTGCGCCTCATCCTGATCGATCCGAAGATGCTCGAAATGAGCGTCTACGAAGGCATTCCGCATCTGCTGTGCCCGG
TCGTCACCGACATGCGCCAGGCAGGCCACGCGCTGAACTGGACCGTCGCCGAGATGGAGCGCCGCTACAAGCTGATGAGC
AAGCTCGGCGTGCGCAATCTCGCCGGCTACAACAACAAGATCGAGGACGCGAAGAAGCGCGAAGAGAAGATCCCGAATCC
GTTCAGCCTGACGCCGGACGATCCGGAGCCGCTCGGCCGGCTGCCGAACATCGTCGTCGTGATCGACGAGCTGGCCGATC
TGATGATGGTCGTCGGCAAGAAGGTGGAGGAGCTGATCGCGCGGATCGCGCAGAAGGCGCGCGCCGCGGGCATCCACCTG
ATTCTCGCGACGCAGCGCCCGTCGGTCGACGTGATCACGGGCCTCATCAAGGCCAATGTGCCGACGCGGATCGCGTTCCA
GGTGTCGTCGAAGATCGATTCGCGCACGATTCTCGACCAGATGGGCGCCGAATCGCTGCTCGGCCAGGGCGATATGCTGT
ACCTGCCGCCCGGTAGCGGGCTGCCCGTGCGCGTGCACGGCGCGTTCGTGTCGGACGACGAAGTGCACCGCGTCGTCGAG
AAGCTCAAGGAGCACGGCGAGCCGAACTACATCGAGGGCCTCCTCGAGGGCGGCACGATCGACGGCGACGAAGGCTCGGC
CGCGGGAACGGGCGAAGCGAACGGCGAGTCCGACCCGTTGTACGACCAGGCGGTCGAGATCGTCATCAAGAACCGGCGCG
CGTCGATCTCGCTCGTGCAGCGCCACCTGCGCATCGGCTACAACCGCGCGGCGCGGCTGCTCGAGCAAATGGAGCAGTCG
GGGCTCGTGTCGGCGATGTCGTCGAGCGGGAACCGCGAAATCCTCACCCCCGCGCGCGACGCGGAGTGA

Upstream 100 bases:

>100_bases
GATACCGTCGCAGATGGGTGCAAAGCCCGCATTATAAAGGGCTGCCCGCCGCGCCGCCGAATGGACTTTTCAATCGGCGC
GATAGCGTCGCGGCGCCGCT

Downstream 100 bases:

>100_bases
ATCCGCGCCGGCGCGCCTGCCGAACGCGCGCCGGCCCTCTACGGAGAAAACCACAGCATGCAGCATCAGTCGTTGGCAGT
TCATACCGGCTCCGGCTTCG

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 822; Mature: 821

Protein sequence:

>822_residues
MAARAHFGPSRPGVTVIYTWRGGAAFTIDRIERSAGCRRFFAARGRLIAPFDGFMAKAPYTAQAQALPHRMSRLLTEIRW
ILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIANWAGRVGAWTADIMLLLFGLSAYWLIVLLGRRVAANYRRITRHDAL
PGEPEKPAGWLAEGFAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGETVARGVAHALGFTGGTLALLIALAIGLSLYF
RFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIEEHEPVTIVPPVVTPAKSERAEKERQQ
PLFTDLPGDSTLPAIALLDPAPTSQETISADTLEFTSRLIEKKLKDFGVEVSVVAAYPGPVVTRYEIEPATGVKGSQIVN
LSKDLARSLSLVSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSEVYADAPSMLTLGLGKDIGGKPVCADLAKMPHLL
VAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWTVAEMERRYKLMS
KLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDDPEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHL
ILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLYLPPGSGLPVRVHGAFVSDDEVHRVVE
KLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRASISLVQRHLRIGYNRAARLLEQMEQS
GLVSAMSSSGNREILTPARDAE

Sequences:

>Translated_822_residues
MAARAHFGPSRPGVTVIYTWRGGAAFTIDRIERSAGCRRFFAARGRLIAPFDGFMAKAPYTAQAQALPHRMSRLLTEIRW
ILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIANWAGRVGAWTADIMLLLFGLSAYWLIVLLGRRVAANYRRITRHDAL
PGEPEKPAGWLAEGFAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGETVARGVAHALGFTGGTLALLIALAIGLSLYF
RFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIEEHEPVTIVPPVVTPAKSERAEKERQQ
PLFTDLPGDSTLPAIALLDPAPTSQETISADTLEFTSRLIEKKLKDFGVEVSVVAAYPGPVVTRYEIEPATGVKGSQIVN
LSKDLARSLSLVSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSEVYADAPSMLTLGLGKDIGGKPVCADLAKMPHLL
VAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWTVAEMERRYKLMS
KLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDDPEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHL
ILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLYLPPGSGLPVRVHGAFVSDDEVHRVVE
KLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRASISLVQRHLRIGYNRAARLLEQMEQS
GLVSAMSSSGNREILTPARDAE
>Mature_821_residues
AARAHFGPSRPGVTVIYTWRGGAAFTIDRIERSAGCRRFFAARGRLIAPFDGFMAKAPYTAQAQALPHRMSRLLTEIRWI
LQVALLAFLLMALLSYSRRDPSWTHAAQVDHIANWAGRVGAWTADIMLLLFGLSAYWLIVLLGRRVAANYRRITRHDALP
GEPEKPAGWLAEGFAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGETVARGVAHALGFTGGTLALLIALAIGLSLYFR
FSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIEEHEPVTIVPPVVTPAKSERAEKERQQP
LFTDLPGDSTLPAIALLDPAPTSQETISADTLEFTSRLIEKKLKDFGVEVSVVAAYPGPVVTRYEIEPATGVKGSQIVNL
SKDLARSLSLVSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSEVYADAPSMLTLGLGKDIGGKPVCADLAKMPHLLV
AGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWTVAEMERRYKLMSK
LGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDDPEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLI
LATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLYLPPGSGLPVRVHGAFVSDDEVHRVVEK
LKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRASISLVQRHLRIGYNRAARLLEQMEQSG
LVSAMSSSGNREILTPARDAE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=493, Percent_Identity=63.4888438133874, Blast_Score=609, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 89630; Mature: 89499

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARAHFGPSRPGVTVIYTWRGGAAFTIDRIERSAGCRRFFAARGRLIAPFDGFMAKAPY
CCCCCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHCCCEECCCCCHHCCCCC
TAQAQALPHRMSRLLTEIRWILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIANWAGRV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
GAWTADIMLLLFGLSAYWLIVLLGRRVAANYRRITRHDALPGEPEKPAGWLAEGFAFVLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
LLASDGIEALRMWSLKVQLPRAPGGVVGETVARGVAHALGFTGGTLALLIALAIGLSLYF
HHHCCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIEEHEPVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEE
IVPPVVTPAKSERAEKERQQPLFTDLPGDSTLPAIALLDPAPTSQETISADTLEFTSRLI
EECCCCCCCCHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
EKKLKDFGVEVSVVAAYPGPVVTRYEIEPATGVKGSQIVNLSKDLARSLSLVSIRVVETI
HHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHEEEEEEEC
PGKNFMALELPNQRRQTVRLSEILGSEVYADAPSMLTLGLGKDIGGKPVCADLAKMPHLL
CCCCEEEEECCCHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCEEE
VAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPVVTDMRQ
EEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHH
AGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDDPEPLGR
CCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHC
LPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANV
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCC
PTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLYLPPGSGLPVRVHGAFVSDDEVHRVVE
CCEEEEEEHHCCCHHHHHHHHCHHHHHCCCCEEEECCCCCCEEEEEEEECCCHHHHHHHH
KLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRASISLVQ
HHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
RHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILTPARDAE
HHHHHCHHHHHHHHHHHHHCCHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure 
AARAHFGPSRPGVTVIYTWRGGAAFTIDRIERSAGCRRFFAARGRLIAPFDGFMAKAPY
CCCCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHCCCEECCCCCHHCCCCC
TAQAQALPHRMSRLLTEIRWILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIANWAGRV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
GAWTADIMLLLFGLSAYWLIVLLGRRVAANYRRITRHDALPGEPEKPAGWLAEGFAFVLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
LLASDGIEALRMWSLKVQLPRAPGGVVGETVARGVAHALGFTGGTLALLIALAIGLSLYF
HHHCCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIEEHEPVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEE
IVPPVVTPAKSERAEKERQQPLFTDLPGDSTLPAIALLDPAPTSQETISADTLEFTSRLI
EECCCCCCCCHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
EKKLKDFGVEVSVVAAYPGPVVTRYEIEPATGVKGSQIVNLSKDLARSLSLVSIRVVETI
HHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHEEEEEEEC
PGKNFMALELPNQRRQTVRLSEILGSEVYADAPSMLTLGLGKDIGGKPVCADLAKMPHLL
CCCCEEEEECCCHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCEEE
VAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPVVTDMRQ
EEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHH
AGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDDPEPLGR
CCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHC
LPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANV
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCC
PTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLYLPPGSGLPVRVHGAFVSDDEVHRVVE
CCEEEEEEHHCCCHHHHHHHHCHHHHHCCCCEEEECCCCCCEEEEEEEECCCHHHHHHHH
KLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRASISLVQ
HHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
RHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILTPARDAE
HHHHHCHHHHHHHHHHHHHCCHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]