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The map label for this gene is fbp [H]

Identifier: 237813358

GI number: 237813358

Start: 3036534

End: 3037550

Strand: Direct

Name: fbp [H]

Synonym: GBP346_A3128

Alternate gene names: 237813358

Gene position: 3036534-3037550 (Clockwise)

Preceding gene: 237813357

Following gene: 237813359

Centisome position: 74.09

GC content: 65.29

Gene sequence:

>1017_bases
ATGTCCATTACCCGACGCACCACGCTGTCCAAGTATCTGATCGAGCAGCAGCGTGAAACCCACAACCTCCCCGCCGACCT
GCGCCTGCTGATCGAAGTGGTCGCGCGCGCGTGCAAGGCGATCAGCTACAACGTGAGCAAGGGCGCGTTGGGCGATGCGC
TCGGCACGGCGGGCAGCGAGAACGTCCAGGGCGAAGTGCAGAAGAAGCTCGACATCCTGTCGAACGAGATCCTGCTCGAC
GCGAACGAATGGGGCGGCAATCTCGCCGCGATGGCGTCCGAGGAGATGGAAACGTTCTTCCCGATCCCGGCGAACTACCC
GCGCGGCGAATACCTGCTCGTGTTCGACCCGCTCGACGGCTCGTCGAACATCGACGTGAACGTGTCGATCGGCACGATCT
TCTCGGTGCTGCGCTGCCCGGACGGCCAGCAGGCGACCGAACAGTCGTTCCTGCAGCCGGGCACGGAACAGGTCGCGGCG
GGCTACGCGGTGTACGGCCCGCAAACCGTGTTCGTGCTGACGACGGGCAACGGCGTGAACTGCTTCACGCTCGATCGCGA
AGTCGGCTCGTGGGTGCTCACGCAAAGCAATCTGCGCATCCCGGAGGACACGCGCGAATACGCGATCAACGCGTCGAACG
CGCGCCACTGGTACGAACCGGTGAAGCGCTACATCGACGAGCTGAACGCGGGCGCCGAAGGCCCGCGCGGCGAGAACTTC
AACATGCGCTGGATCGCGTCGATGGTCGCCGACGTGCACCGTATCCTGAACCGCGGCGGCATCTTCATGTACCCGGCCGA
CAAGCGCACGCCGGATCGCCCGGGCAAGCTGCGGCTGATGTACGAGGCGAATCCGATGTCGTTCATCGTCGAGCAGGCGG
GCGGCGCGGCGACGACGGGCCTGAAGCGGATCCTCGACGTGCAGCCGACGGGCCTGCACCAGCGCGTGCCGGTGATTCTC
GGCTCGAAGAACGAAGTCGAGCGCGTCGCGCGTTATCACGAGCAAGCGCAGTCGTAA

Upstream 100 bases:

>100_bases
TTTTCGCCGAAAAACCGTCGGCCGCCGGTCGCCGCGGGTAAAATCGAGCCTATTCCTATCCCAACATCCCATGCATTCGT
CAGCCTCTCGGAGTTCCCCC

Downstream 100 bases:

>100_bases
CGCAACGGCGACGTCGATGGGGCGGCGGGACCGCGCCCCCATCGCGTCGAACGGACCGGCGCGTCGAGCGGTGCGTGCCG
GCGCGCTCGCGGACTGACCG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSITRRTTLSKYLIEQQRETHNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLD
ANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGQQATEQSFLQPGTEQVAA
GYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNLRIPEDTREYAINASNARHWYEPVKRYIDELNAGAEGPRGENF
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGLKRILDVQPTGLHQRVPVIL
GSKNEVERVARYHEQAQS

Sequences:

>Translated_338_residues
MSITRRTTLSKYLIEQQRETHNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLD
ANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGQQATEQSFLQPGTEQVAA
GYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNLRIPEDTREYAINASNARHWYEPVKRYIDELNAGAEGPRGENF
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGLKRILDVQPTGLHQRVPVIL
GSKNEVERVARYHEQAQS
>Mature_337_residues
SITRRTTLSKYLIEQQRETHNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLDA
NEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGQQATEQSFLQPGTEQVAAG
YAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNLRIPEDTREYAINASNARHWYEPVKRYIDELNAGAEGPRGENFN
MRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGLKRILDVQPTGLHQRVPVILG
SKNEVERVARYHEQAQS

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=334, Percent_Identity=42.2155688622754, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI16579888, Length=334, Percent_Identity=42.2155688622754, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI22907028, Length=324, Percent_Identity=42.2839506172839, Blast_Score=250, Evalue=1e-66,
Organism=Escherichia coli, GI1790679, Length=327, Percent_Identity=44.954128440367, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17508131, Length=329, Percent_Identity=44.6808510638298, Blast_Score=280, Evalue=9e-76,
Organism=Saccharomyces cerevisiae, GI6323409, Length=335, Percent_Identity=40, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI19921562, Length=325, Percent_Identity=43.6923076923077, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI45550998, Length=325, Percent_Identity=43.6923076923077, Blast_Score=259, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37378; Mature: 37247

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITRRTTLSKYLIEQQRETHNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSE
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
NVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDG
CCHHHHHHHHHHHCCEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCCEEEEEECCCC
SSNIDVNVSIGTIFSVLRCPDGQQATEQSFLQPGTEQVAAGYAVYGPQTVFVLTTGNGVN
CCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCEEEECCCEEEEEECCCCEE
CFTLDREVGSWVLTQSNLRIPEDTREYAINASNARHWYEPVKRYIDELNAGAEGPRGENF
EEEECCCCCCEEEECCCCCCCCCHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTG
CHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHCCCHHHHH
LKRILDVQPTGLHQRVPVILGSKNEVERVARYHEQAQS
HHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SITRRTTLSKYLIEQQRETHNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSE
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
NVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDG
CCHHHHHHHHHHHCCEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCCEEEEEECCCC
SSNIDVNVSIGTIFSVLRCPDGQQATEQSFLQPGTEQVAAGYAVYGPQTVFVLTTGNGVN
CCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCEEEECCCEEEEEECCCCEE
CFTLDREVGSWVLTQSNLRIPEDTREYAINASNARHWYEPVKRYIDELNAGAEGPRGENF
EEEECCCCCCEEEECCCCCCCCCHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTG
CHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHCCCHHHHH
LKRILDVQPTGLHQRVPVILGSKNEVERVARYHEQAQS
HHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA