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The map label for this gene is nudL [H]

Identifier: 237813266

GI number: 237813266

Start: 2947856

End: 2948806

Strand: Reverse

Name: nudL [H]

Synonym: GBP346_A3033

Alternate gene names: 237813266

Gene position: 2948806-2947856 (Counterclockwise)

Preceding gene: 237813269

Following gene: 237813265

Centisome position: 71.95

GC content: 69.82

Gene sequence:

>951_bases
ATGGCGCACGACGCACGGCGCACGGCACACGGCACACGGCGCACGGCCGACGACGCATGGCGCGGCCGCTTGCCTGCGTT
CGGCCGGCGAGCCGCGGCCGATAGCGTTTCCTCACCCTCGTCACGCAACGCGGCCCGACAGGCGCGCCGTCCCATCGCGC
GGCGCATGCCGCGCTCGACGGCGGCGCCATCCGGCGAGCGACTCGCCGCGCGCTTTTTTCTTTTCGGCGCGACAATATGG
CCATATCCATTCCGAGCAGAGCTTGACTTGATCCGTCGCCCCATCATCGACCCTGAAGTGCTGCCGATCGAGACGACCGG
CGCCGACCTGCCAGTCGTCCGGCCGTCGTCGATGACGCCGGCCGGCCTGCGCGAGCGTTTCGCCGAGCCGCCCGAATGGA
CGCAGGAGCCCGCCGAGGCGCAGCTTGCCCACGGCGTCGATCCGCGCAGCGCGGCCGTGCTCGTGCCGCTCGTCGTGCGT
GAACGCGGCCTGACGGTGCTGCTCACGCAGCGTGCGGACCACCTGAACGATCATGCCGGCCAGATCAGCTTTCCGGGCGG
GCGCCGCGAGCCCGATGACCGCGACGCGAACGCCACCGCGCTGCGCGAGGCGCGCGAGGAAATCGCGCTTGCCCACGAGC
GCGTCGAGCTGCTGGGCGCGCTGCCCGACTATCTGACAGGCACGGGCTTTTGCGTGACGCCCGTCGTCGGGCTCGTCCAT
CCGCCATTCACGGTGCAGCCGGATACGCTCGAAGTGGCCGAGATCTTCGAGGTGCCGCTCGATTTCCTGATGAATCCCGC
GCATCACCAGATCAGGGTGTTGCGCTGGGAGGGCGGCGAGCGGCGCTTTTTCGCGATGCCGTATCCGCGCGGGCCGGTCG
GCGGCCAGTATTTCATCTGGGGCGCGACGGCCGGCATGCTGCGCAACCTGTATCGCTTTCTGTCGGCCTAA

Upstream 100 bases:

>100_bases
GGGGCGTGTTCATGCCGCCGCACCCGAATCCGCGAGCGCGGCGTGGACCTCGATACGCGCCCGTCGCCGCATCCGCCCAT
TCGCCCATTCGCCCATTCGC

Downstream 100 bases:

>100_bases
TGGCGCGCGCCACAGTCGGTGCACGCCGGAGCCATCCGTTGCGCCCGCTGTGCTATCTTTACGCGAAAAATCAATCATCC
AGAACGGCACGGCCCTTCGC

Product: pyrophosphatase, MutT/nudix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MAHDARRTAHGTRRTADDAWRGRLPAFGRRAAADSVSSPSSRNAARQARRPIARRMPRSTAAPSGERLAARFFLFGATIW
PYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTPAGLRERFAEPPEWTQEPAEAQLAHGVDPRSAAVLVPLVVR
ERGLTVLLTQRADHLNDHAGQISFPGGRREPDDRDANATALREAREEIALAHERVELLGALPDYLTGTGFCVTPVVGLVH
PPFTVQPDTLEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYPRGPVGGQYFIWGATAGMLRNLYRFLSA

Sequences:

>Translated_316_residues
MAHDARRTAHGTRRTADDAWRGRLPAFGRRAAADSVSSPSSRNAARQARRPIARRMPRSTAAPSGERLAARFFLFGATIW
PYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTPAGLRERFAEPPEWTQEPAEAQLAHGVDPRSAAVLVPLVVR
ERGLTVLLTQRADHLNDHAGQISFPGGRREPDDRDANATALREAREEIALAHERVELLGALPDYLTGTGFCVTPVVGLVH
PPFTVQPDTLEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYPRGPVGGQYFIWGATAGMLRNLYRFLSA
>Mature_315_residues
AHDARRTAHGTRRTADDAWRGRLPAFGRRAAADSVSSPSSRNAARQARRPIARRMPRSTAAPSGERLAARFFLFGATIWP
YPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTPAGLRERFAEPPEWTQEPAEAQLAHGVDPRSAAVLVPLVVRE
RGLTVLLTQRADHLNDHAGQISFPGGRREPDDRDANATALREAREEIALAHERVELLGALPDYLTGTGFCVTPVVGLVHP
PFTVQPDTLEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYPRGPVGGQYFIWGATAGMLRNLYRFLSA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=155, Percent_Identity=38.0645161290323, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI1788115, Length=167, Percent_Identity=42.5149700598802, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536993, Length=120, Percent_Identity=38.3333333333333, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI18859683, Length=174, Percent_Identity=37.3563218390805, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 35078; Mature: 34947

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHDARRTAHGTRRTADDAWRGRLPAFGRRAAADSVSSPSSRNAARQARRPIARRMPRST
CCCCHHHHHCCCCCCCCHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
AAPSGERLAARFFLFGATIWPYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTP
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCCCCC
AGLRERFAEPPEWTQEPAEAQLAHGVDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAG
HHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEHHHHHHCCCCEEEEECCHHHHCCCCC
QISFPGGRREPDDRDANATALREAREEIALAHERVELLGALPDYLTGTGFCVTPVVGLVH
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHCC
PPFTVQPDTLEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYPRGPVGGQYFIW
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCEEEEE
GATAGMLRNLYRFLSA
CCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AHDARRTAHGTRRTADDAWRGRLPAFGRRAAADSVSSPSSRNAARQARRPIARRMPRST
CCCHHHHHCCCCCCCCHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
AAPSGERLAARFFLFGATIWPYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTP
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCCCCC
AGLRERFAEPPEWTQEPAEAQLAHGVDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAG
HHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEHHHHHHCCCCEEEEECCHHHHCCCCC
QISFPGGRREPDDRDANATALREAREEIALAHERVELLGALPDYLTGTGFCVTPVVGLVH
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHCC
PPFTVQPDTLEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYPRGPVGGQYFIW
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCEEEEE
GATAGMLRNLYRFLSA
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]