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The map label for this gene is yhfN [H]

Identifier: 237813262

GI number: 237813262

Start: 2944064

End: 2945323

Strand: Direct

Name: yhfN [H]

Synonym: GBP346_A3029

Alternate gene names: 237813262

Gene position: 2944064-2945323 (Clockwise)

Preceding gene: 237813260

Following gene: 237813263

Centisome position: 71.83

GC content: 67.3

Gene sequence:

>1260_bases
ATGTCCGCCTATACCTTCACCCTGCTCTTCGCCGTCGCGATCGTCGCGATGACGGGCACCAAGCTGTGGCTCGCGTCGCG
GCAGGTCCGCTTCGTCGCCGCGCATCGCGCCCGCGTGCCCGCGCAGTTCCGCGAAACGATCCCGCTCGCCGCGCACCAGC
GCGCCGCCGACTACACGATCGAACGCACGCGGCTCACGATGTTCGAGATCGTCGTCGCCTCGGCGGTGCTTGTCGGTCTC
ACGCTCCTCGGGGGCGTCGGCGCGCTCGATTCGCTGCTCGCCGGCTGGCTCGGCCACGGCTACGGCCAGCAGGTGGCGCT
CGTCGCCGCGGTGCTCGTGATCTCCAGCGCGGCCGATCTGCCGTTCGAGTACTACCGCCAGTTCGGCATCGAAGAGCGCT
TCGGCTTCAACCGGATGACGAAGCGGCTGTTCTTCACCGATCTCGCGAAGAACGCGCTGCTCGGCGCGGCGCTCGGCCTG
CCGCTCCTGTTCGTCGTGCTGTGGCTGATGAACCAGGCGGGCGCGCTATGGTGGCTGTGGACGTGGATCGTGTGGGTCGG
CTTCCAGATGCTCGTTCTCGTGCTCTACCCGACCTTCATCGCGCCGATCTTCAACAAGTTCGAGCCGCTTTCCGACGACG
CGCTGCGCGCGCGCATCGAAGGGCTGATGAAGCGCTGCGGCTTCGCGGCGAAGGGCCTCTTCGTGATGGACGGCAGCCGC
CGCTCCGCGCACGGCAACGCGTACTTCACGGGCTTCGGCGCGTCGAAGCGGATCGTGTTCTTCGATACGTTGCTCGCCCG
CCTGACGGGTGGCGAGATCGAAGCGGTGCTCGCGCACGAGCTCGGCCATTTCAAGCGCCGCCACGTGATGAAGCGGATGC
TGTGGACCTTCGCGCTCAGCCTCGCGCTGCTCGCGCTGCTCGGCTGGCTCGCGCAGCGCGCGTGGTTCTACACGGGCCTC
GGCGTGATGCCGTCGCTCTCGGGCAGCAACGCGGGCATCGCGCTCGTGCTGTTCTTCCTGTCGATGCCGGTGTTCCTGTT
CTTCGTCACGCCGCTTGGCAGCCTGAGCTCGCGCAAGCACGAGTTCGAGGCCGACGCGTTCGCCGCGAGCCAGACCGATG
CGCGCGATCTCGTCAACGCGCTCGTGAAACTCTACGAAGACAATGCGTCGACGCTCACGCCCGACCCCGTCTACACCGCG
TTCTACTACTCGCATCCGCCCGCGTCCCAGCGTATCGACCGGCTGCTCCAGCACTCATGA

Upstream 100 bases:

>100_bases
AGCGGACGGCGCGCGCGCCGCCGGGCGGGCCGGCAAACAACAAGCGGGCCGGGTCCGCAAGAACATATAATTCTCGCATA
GATACCCACCAGCGCCTTCG

Downstream 100 bases:

>100_bases
AGCGCGCGCCGACGAAGCAGCCGGCCAAGCCCGCCGCGCGCGGCGGTGAACGCGCGCAGGGGCGCGTGATCGCCGCGCAC
GGGCGCCACTACATCGTCGC

Product: peptidase, M48 family

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSAYTFTLLFAVAIVAMTGTKLWLASRQVRFVAAHRARVPAQFRETIPLAAHQRAADYTIERTRLTMFEIVVASAVLVGL
TLLGGVGALDSLLAGWLGHGYGQQVALVAAVLVISSAADLPFEYYRQFGIEERFGFNRMTKRLFFTDLAKNALLGAALGL
PLLFVVLWLMNQAGALWWLWTWIVWVGFQMLVLVLYPTFIAPIFNKFEPLSDDALRARIEGLMKRCGFAAKGLFVMDGSR
RSAHGNAYFTGFGASKRIVFFDTLLARLTGGEIEAVLAHELGHFKRRHVMKRMLWTFALSLALLALLGWLAQRAWFYTGL
GVMPSLSGSNAGIALVLFFLSMPVFLFFVTPLGSLSSRKHEFEADAFAASQTDARDLVNALVKLYEDNASTLTPDPVYTA
FYYSHPPASQRIDRLLQHS

Sequences:

>Translated_419_residues
MSAYTFTLLFAVAIVAMTGTKLWLASRQVRFVAAHRARVPAQFRETIPLAAHQRAADYTIERTRLTMFEIVVASAVLVGL
TLLGGVGALDSLLAGWLGHGYGQQVALVAAVLVISSAADLPFEYYRQFGIEERFGFNRMTKRLFFTDLAKNALLGAALGL
PLLFVVLWLMNQAGALWWLWTWIVWVGFQMLVLVLYPTFIAPIFNKFEPLSDDALRARIEGLMKRCGFAAKGLFVMDGSR
RSAHGNAYFTGFGASKRIVFFDTLLARLTGGEIEAVLAHELGHFKRRHVMKRMLWTFALSLALLALLGWLAQRAWFYTGL
GVMPSLSGSNAGIALVLFFLSMPVFLFFVTPLGSLSSRKHEFEADAFAASQTDARDLVNALVKLYEDNASTLTPDPVYTA
FYYSHPPASQRIDRLLQHS
>Mature_418_residues
SAYTFTLLFAVAIVAMTGTKLWLASRQVRFVAAHRARVPAQFRETIPLAAHQRAADYTIERTRLTMFEIVVASAVLVGLT
LLGGVGALDSLLAGWLGHGYGQQVALVAAVLVISSAADLPFEYYRQFGIEERFGFNRMTKRLFFTDLAKNALLGAALGLP
LLFVVLWLMNQAGALWWLWTWIVWVGFQMLVLVLYPTFIAPIFNKFEPLSDDALRARIEGLMKRCGFAAKGLFVMDGSRR
SAHGNAYFTGFGASKRIVFFDTLLARLTGGEIEAVLAHELGHFKRRHVMKRMLWTFALSLALLALLGWLAQRAWFYTGLG
VMPSLSGSNAGIALVLFFLSMPVFLFFVTPLGSLSSRKHEFEADAFAASQTDARDLVNALVKLYEDNASTLTPDPVYTAF
YYSHPPASQRIDRLLQHS

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=440, Percent_Identity=27.7272727272727, Blast_Score=178, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17505484, Length=422, Percent_Identity=29.6208530805687, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6322577, Length=309, Percent_Identity=37.5404530744337, Blast_Score=212, Evalue=8e-56,
Organism=Drosophila melanogaster, GI19922414, Length=439, Percent_Identity=30.2961275626424, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI78707252, Length=411, Percent_Identity=26.5206812652068, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI78707254, Length=411, Percent_Identity=26.5206812652068, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24654305, Length=431, Percent_Identity=25.9860788863109, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 46579; Mature: 46448

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAYTFTLLFAVAIVAMTGTKLWLASRQVRFVAAHRARVPAQFRETIPLAAHQRAADYTI
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCHH
ERTRLTMFEIVVASAVLVGLTLLGGVGALDSLLAGWLGHGYGQQVALVAAVLVISSAADL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
PFEYYRQFGIEERFGFNRMTKRLFFTDLAKNALLGAALGLPLLFVVLWLMNQAGALWWLW
CHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TWIVWVGFQMLVLVLYPTFIAPIFNKFEPLSDDALRARIEGLMKRCGFAAKGLFVMDGSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHCCEEEECCCC
RSAHGNAYFTGFGASKRIVFFDTLLARLTGGEIEAVLAHELGHFKRRHVMKRMLWTFALS
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALLALLGWLAQRAWFYTGLGVMPSLSGSNAGIALVLFFLSMPVFLFFVTPLGSLSSRKH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCH
EFEADAFAASQTDARDLVNALVKLYEDNASTLTPDPVYTAFYYSHPPASQRIDRLLQHS
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SAYTFTLLFAVAIVAMTGTKLWLASRQVRFVAAHRARVPAQFRETIPLAAHQRAADYTI
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCHH
ERTRLTMFEIVVASAVLVGLTLLGGVGALDSLLAGWLGHGYGQQVALVAAVLVISSAADL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
PFEYYRQFGIEERFGFNRMTKRLFFTDLAKNALLGAALGLPLLFVVLWLMNQAGALWWLW
CHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TWIVWVGFQMLVLVLYPTFIAPIFNKFEPLSDDALRARIEGLMKRCGFAAKGLFVMDGSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHCCEEEECCCC
RSAHGNAYFTGFGASKRIVFFDTLLARLTGGEIEAVLAHELGHFKRRHVMKRMLWTFALS
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALLALLGWLAQRAWFYTGLGVMPSLSGSNAGIALVLFFLSMPVFLFFVTPLGSLSSRKH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCH
EFEADAFAASQTDARDLVNALVKLYEDNASTLTPDPVYTAFYYSHPPASQRIDRLLQHS
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]