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The map label for this gene is nhaA [H]

Identifier: 237813214

GI number: 237813214

Start: 2900613

End: 2901530

Strand: Reverse

Name: nhaA [H]

Synonym: GBP346_A2979

Alternate gene names: 237813214

Gene position: 2901530-2900613 (Counterclockwise)

Preceding gene: 237813215

Following gene: 237813211

Centisome position: 70.79

GC content: 68.41

Gene sequence:

>918_bases
GTGCTCGAGCGCGTCGCGCTCGCGGCGATCAAGGAGCAGCGCGCCGCGCGGCGCTGGAGGATCTTCTTTCGCTTCGCGTT
CCTCGCCGTGCTCGGCGCGCTCGCGTTCGCGTTCCTCAGCGTGTCCGGCGACGGCAGCAAGCTCGCGAGCGGCCGCCACA
CGGCGGTCGTGACGATCGACGGCGAGATCGCCGCGAGCACCAACGCGAACGCCGAGGACATCAACACGGCGCTCGACAGC
GCGTTCGAGGATTCGGGCACGGTCGGCGTCGTGCTGAAGATCAACAGCCCGGGCGGCAGCCCGGTGCAGGCGGGCATCGT
CTACGACGAGATCCGGCGGCTGCGCAAGAAGTATCCGGCGAAGCCGCTTTACGTCGTCGTCTCCGACATGTGCGCGTCGG
GCGGCTACTACATCGCGGCGGCGGCGGACAAGATCTACGTCGACAAGGCGAGCATCGTCGGCTCGATCGGCGTGCTGATG
GACGGGTTCGGCTTCACCGGCCTGATGGGCAAGCTGGGCGTCGAGCGGCGCCTGCATACGTCGGGCGAGAACAAGGGCTT
CTTCGATCCGTTCTCGCCGGAGACGCCGAAGATGGATGCGCACGCGCAGGAAATGCTCGACGAGATCCACGCGCAGTTCA
TCAAGGCGGTGAAGGACGGCCGCGGCGCGCGCCTGCACGAATCGCCGGACATTTTCTCCGGGCTTTTCTGGACGGGCGCG
AAGAGCATCGAGCTCGGCCTCGCCGACGATTACGGGACGACCGATACCGTCGCGCGCGACGTGCTGAAGGCGCCCGACCT
CGTCGACTACACGGTCAAGGAAAGCCTGACCGATCGCGTCGCGCGCCGCTTCGGCGCGGCGCTCGGCAAGGCCGCGCTGA
AGGCGGCCGTCGCCGGCGGCGAGCTGAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
CCACTGACTTTCACGCATGTCCGATCAAATCAATCCGCCCGATTCGTCTTCGTCCCCCGCTGCGAACGCCGCCCCCCGAG
AACCGAGTTGGGAGCGCGCC

Downstream 100 bases:

>100_bases
AGGCGCGGGCCGCTTCGCGCGGCTCGCGCCGGTTCGCGTCAGCTCGCGAGCAGCAGGAAGATCGCGGGGCGCTTGTGCAG
ATCGGGCACGGGCGCCTTTT

Product: peptidase, U7 family protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGSKLASGRHTAVVTIDGEIAASTNANAEDINTALDS
AFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCASGGYYIAAAADKIYVDKASIVGSIGVLM
DGFGFTGLMGKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQFIKAVKDGRGARLHESPDIFSGLFWTGA
KSIELGLADDYGTTDTVARDVLKAPDLVDYTVKESLTDRVARRFGAALGKAALKAAVAGGELKLR

Sequences:

>Translated_305_residues
MLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGSKLASGRHTAVVTIDGEIAASTNANAEDINTALDS
AFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCASGGYYIAAAADKIYVDKASIVGSIGVLM
DGFGFTGLMGKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQFIKAVKDGRGARLHESPDIFSGLFWTGA
KSIELGLADDYGTTDTVARDVLKAPDLVDYTVKESLTDRVARRFGAALGKAALKAAVAGGELKLR
>Mature_305_residues
MLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGSKLASGRHTAVVTIDGEIAASTNANAEDINTALDS
AFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCASGGYYIAAAADKIYVDKASIVGSIGVLM
DGFGFTGLMGKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQFIKAVKDGRGARLHESPDIFSGLFWTGA
KSIELGLADDYGTTDTVARDVLKAPDLVDYTVKESLTDRVARRFGAALGKAALKAAVAGGELKLR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=221, Percent_Identity=33.4841628959276, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 32596; Mature: 32596

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGSKLASGRHTAVVTID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEC
GEIAASTNANAEDINTALDSAFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPA
CCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCC
KPLYVVVSDMCASGGYYIAAAADKIYVDKASIVGSIGVLMDGFGFTGLMGKLGVERRLHT
CCCEEEEEHHHCCCCEEEEEECCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
SGENKGFFDPFSPETPKMDAHAQEMLDEIHAQFIKAVKDGRGARLHESPDIFSGLFWTGA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
KSIELGLADDYGTTDTVARDVLKAPDLVDYTVKESLTDRVARRFGAALGKAALKAAVAGG
CEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ELKLR
CEEEC
>Mature Secondary Structure
MLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGSKLASGRHTAVVTID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEC
GEIAASTNANAEDINTALDSAFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPA
CCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCC
KPLYVVVSDMCASGGYYIAAAADKIYVDKASIVGSIGVLMDGFGFTGLMGKLGVERRLHT
CCCEEEEEHHHCCCCEEEEEECCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
SGENKGFFDPFSPETPKMDAHAQEMLDEIHAQFIKAVKDGRGARLHESPDIFSGLFWTGA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
KSIELGLADDYGTTDTVARDVLKAPDLVDYTVKESLTDRVARRFGAALGKAALKAAVAGG
CEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ELKLR
CEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA