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The map label for this gene is fabH [H]

Identifier: 237813208

GI number: 237813208

Start: 2895821

End: 2896810

Strand: Reverse

Name: fabH [H]

Synonym: GBP346_A2973

Alternate gene names: 237813208

Gene position: 2896810-2895821 (Counterclockwise)

Preceding gene: 237813209

Following gene: 237813207

Centisome position: 70.68

GC content: 66.87

Gene sequence:

>990_bases
ATGGCCCAATCGACCCTCTATTCCCGCGTGCTCGGCACGGGTAGCTATCTGCCGCCCGATCGCGTCACGAATCAAGAACT
CGCCGATCGTCTCGCGAAGGACGGCATCGAGACGAGCGACGAGTGGATCGTCGCGCGCACGGGCATCCGCGCGCGGCACT
TCGCCGCGCCCGACGTGACGACGAGCGATCTCGCGCTCGTCGCCGCGCAGCGCGCGATCGAGGCGGCCGACGTCGATCCG
CAGTCGATCGACCTCATCATCGTCGCGACGTCGACGCCTGATTTCGTTTTCCCGAGCACCGCGTGCCTGCTGCAGAACAA
GCTCGGCATCAAGAACGGCGGCGCCGCGTTCGACGTGCAGGCGGTATGTTCGGGCTTCGCCTACGCGCTCGCGACGGCCG
ACAGCTTCATCCGCACGGGGCAGCACCGCACGGCGCTCGTCATCGGCGCGGAGACGTTCTCGCGCATTCTCGATTTCAAG
GACCGTACGACCTGCGTGCTGTTCGGCGACGGCGCGGGCGCCGTCGTGCTGTCGGCGTCCGAAGAGCCGGGCATCCTCGG
CAGCGCGCTGCATGCGGACGGCAGCTATTCGAACATTCTCTGCACGCCGGGCAACGTGAACCGCGGCGTCATCGCGGGCA
GCGCGTTCCTGCACATGGACGGCCAGGCCGTCTTCAAGCTTGCCGTGAACGTGCTCGAGAAAGTCGCGGTCGAAGCGCTG
TCGAAGGCGGAGCTCGCGTCGGAACAGGTCGATTGGCTGATTCCGCACCAGGCCAATATCCGTATCATGACAAGCACGTG
CCGCAAGCTCGGCCTGCCGCAGGAACGCATGATCGTCACCGTCGACGAGCACGGCAACACGTCCGCCGCATCGATTCCGC
TCGCACTCGACGTCGCCGTGCGCGACGGCCGCATCAAGCGCGGCCAGCACGTGCTGATCGAAGGCGTCGGCGGCGGCTTC
ACGTGGGGCGCGTCGGTCTTCCGCTTCTGA

Upstream 100 bases:

>100_bases
CGCTCGGCGAAAGCGGGCGCGACGCGAACGGAGCGGGGCAGGCGAGTCCGTCCGCAGGCCAGCCAGCCGAGCCCTCCGCC
GCGCTTTCCTCGAAGACATA

Downstream 100 bases:

>100_bases
CGGCCCTTCTTCGCATCCCATCGGCGCGCCATTCAAGCGCGCCGCTCGAATCGATTCAATTGGGGACGATATGAAATTCG
CATTCGTTTTTCCGGGCCAG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAQSTLYSRVLGTGSYLPPDRVTNQELADRLAKDGIETSDEWIVARTGIRARHFAAPDVTTSDLALVAAQRAIEAADVDP
QSIDLIIVATSTPDFVFPSTACLLQNKLGIKNGGAAFDVQAVCSGFAYALATADSFIRTGQHRTALVIGAETFSRILDFK
DRTTCVLFGDGAGAVVLSASEEPGILGSALHADGSYSNILCTPGNVNRGVIAGSAFLHMDGQAVFKLAVNVLEKVAVEAL
SKAELASEQVDWLIPHQANIRIMTSTCRKLGLPQERMIVTVDEHGNTSAASIPLALDVAVRDGRIKRGQHVLIEGVGGGF
TWGASVFRF

Sequences:

>Translated_329_residues
MAQSTLYSRVLGTGSYLPPDRVTNQELADRLAKDGIETSDEWIVARTGIRARHFAAPDVTTSDLALVAAQRAIEAADVDP
QSIDLIIVATSTPDFVFPSTACLLQNKLGIKNGGAAFDVQAVCSGFAYALATADSFIRTGQHRTALVIGAETFSRILDFK
DRTTCVLFGDGAGAVVLSASEEPGILGSALHADGSYSNILCTPGNVNRGVIAGSAFLHMDGQAVFKLAVNVLEKVAVEAL
SKAELASEQVDWLIPHQANIRIMTSTCRKLGLPQERMIVTVDEHGNTSAASIPLALDVAVRDGRIKRGQHVLIEGVGGGF
TWGASVFRF
>Mature_328_residues
AQSTLYSRVLGTGSYLPPDRVTNQELADRLAKDGIETSDEWIVARTGIRARHFAAPDVTTSDLALVAAQRAIEAADVDPQ
SIDLIIVATSTPDFVFPSTACLLQNKLGIKNGGAAFDVQAVCSGFAYALATADSFIRTGQHRTALVIGAETFSRILDFKD
RTTCVLFGDGAGAVVLSASEEPGILGSALHADGSYSNILCTPGNVNRGVIAGSAFLHMDGQAVFKLAVNVLEKVAVEALS
KAELASEQVDWLIPHQANIRIMTSTCRKLGLPQERMIVTVDEHGNTSAASIPLALDVAVRDGRIKRGQHVLIEGVGGGFT
WGASVFRF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=324, Percent_Identity=52.1604938271605, Blast_Score=338, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34853; Mature: 34722

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSTLYSRVLGTGSYLPPDRVTNQELADRLAKDGIETSDEWIVARTGIRARHFAAPDVT
CCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCC
TSDLALVAAQRAIEAADVDPQSIDLIIVATSTPDFVFPSTACLLQNKLGIKNGGAAFDVQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCEEEHH
AVCSGFAYALATADSFIRTGQHRTALVIGAETFSRILDFKDRTTCVLFGDGAGAVVLSAS
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEECC
EEPGILGSALHADGSYSNILCTPGNVNRGVIAGSAFLHMDGQAVFKLAVNVLEKVAVEAL
CCCCCEEEEEECCCCCCEEEECCCCCCCCEEECEEEEEECCHHHHHHHHHHHHHHHHHHH
SKAELASEQVDWLIPHQANIRIMTSTCRKLGLPQERMIVTVDEHGNTSAASIPLALDVAV
HHHHHHHHCCCEECCCCCCEEEEEHHHHHHCCCCHHEEEEEECCCCCCCEECCEEEEEEE
RDGRIKRGQHVLIEGVGGGFTWGASVFRF
ECCCCCCCCEEEEEECCCCEEHHHHHHCC
>Mature Secondary Structure 
AQSTLYSRVLGTGSYLPPDRVTNQELADRLAKDGIETSDEWIVARTGIRARHFAAPDVT
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCC
TSDLALVAAQRAIEAADVDPQSIDLIIVATSTPDFVFPSTACLLQNKLGIKNGGAAFDVQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCEEEHH
AVCSGFAYALATADSFIRTGQHRTALVIGAETFSRILDFKDRTTCVLFGDGAGAVVLSAS
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEECC
EEPGILGSALHADGSYSNILCTPGNVNRGVIAGSAFLHMDGQAVFKLAVNVLEKVAVEAL
CCCCCEEEEEECCCCCCEEEECCCCCCCCEEECEEEEEECCHHHHHHHHHHHHHHHHHHH
SKAELASEQVDWLIPHQANIRIMTSTCRKLGLPQERMIVTVDEHGNTSAASIPLALDVAV
HHHHHHHHCCCEECCCCCCEEEEEHHHHHHCCCCHHEEEEEECCCCCCCEECCEEEEEEE
RDGRIKRGQHVLIEGVGGGFTWGASVFRF
ECCCCCCCCEEEEEECCCCEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA