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The map label for this gene is rpoE [H]

Identifier: 237813202

GI number: 237813202

Start: 2891050

End: 2891649

Strand: Reverse

Name: rpoE [H]

Synonym: GBP346_A2967

Alternate gene names: 237813202

Gene position: 2891649-2891050 (Counterclockwise)

Preceding gene: 237813203

Following gene: 237813201

Centisome position: 70.55

GC content: 61.5

Gene sequence:

>600_bases
GTGAGTGAAAAAGAAATCGATCAGGTACTGGTCGAACGCGTACAGAATGGCGACAAGGCGGCGTTCGAACTCCTGGTCTC
CAAATACCACCGCAAGATCATCCGGCTGATCTCGCGCCTCGTGCGGGATCCCGCGGAGGTCGAGGACGTGGCCCAGGACG
CGTTCATCAAGGCGTATCGCGCGTTGCCGCAGTTTCGCGGCGAGTCGGCGTTCTACACGTGGTTGTACCGGATTGCCGTC
AATACGGCGAAGAACTACCTTGCGACCCAGGGGCGCCGGGCGCCCACGTCCACCGACGCGGACGCCGAAGAGGCTGAAAC
TTTCTCCGACGCGGACCAACTAAGGGATATCAACACGCCTGAGTCGATGTTGATGAGCAAGCAGATCGCCCAAACGGTCA
ACGCCGCGATGGCGCTGTTGCCGGAAGAGTTGCGAACGGCCATCACGCTGCGCGAGATCGAAGGTCTGAGCTACGAAGAG
ATCGCGGAGATGATGGGTTGCCCGATCGGCACCGTTCGCTCGCGGATCTTTCGCGCCCGCGAGGCGATCGCGGCAAAATT
GCGGCCGCTGCTCGATACGCCGGAAGGCAGGCGCTGGTAA

Upstream 100 bases:

>100_bases
GCGCGGCAGGCCGCTTCCGGTCGAAAACGCCCATGAGCGCCTCGAGCGGGAACGTTACAATAGCGCTCCGCGTTGCTTCC
CTCGTTTACGGATTTGTCAG

Downstream 100 bases:

>100_bases
GCGCCTGCGGCGAATCGAAGCGGCTTGGGGTCTAGTTACGGAGTCGTGTGTCACGACGGGGTGTGTGCAAGATGGGGAGC
ATCATGGGGTCGGTCTCTAC

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSEKEIDQVLVERVQNGDKAAFELLVSKYHRKIIRLISRLVRDPAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAV
NTAKNYLATQGRRAPTSTDADAEEAETFSDADQLRDINTPESMLMSKQIAQTVNAAMALLPEELRTAITLREIEGLSYEE
IAEMMGCPIGTVRSRIFRAREAIAAKLRPLLDTPEGRRW

Sequences:

>Translated_199_residues
MSEKEIDQVLVERVQNGDKAAFELLVSKYHRKIIRLISRLVRDPAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAV
NTAKNYLATQGRRAPTSTDADAEEAETFSDADQLRDINTPESMLMSKQIAQTVNAAMALLPEELRTAITLREIEGLSYEE
IAEMMGCPIGTVRSRIFRAREAIAAKLRPLLDTPEGRRW
>Mature_198_residues
SEKEIDQVLVERVQNGDKAAFELLVSKYHRKIIRLISRLVRDPAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAVN
TAKNYLATQGRRAPTSTDADAEEAETFSDADQLRDINTPESMLMSKQIAQTVNAAMALLPEELRTAITLREIEGLSYEEI
AEMMGCPIGTVRSRIFRAREAIAAKLRPLLDTPEGRRW

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=191, Percent_Identity=62.303664921466, Blast_Score=238, Evalue=2e-64,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22594; Mature: 22463

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKEIDQVLVERVQNGDKAAFELLVSKYHRKIIRLISRLVRDPAEVEDVAQDAFIKAYR
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ALPQFRGESAFYTWLYRIAVNTAKNYLATQGRRAPTSTDADAEEAETFSDADQLRDINTP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
ESMLMSKQIAQTVNAAMALLPEELRTAITLREIEGLSYEEIAEMMGCPIGTVRSRIFRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHH
EAIAAKLRPLLDTPEGRRW
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SEKEIDQVLVERVQNGDKAAFELLVSKYHRKIIRLISRLVRDPAEVEDVAQDAFIKAYR
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ALPQFRGESAFYTWLYRIAVNTAKNYLATQGRRAPTSTDADAEEAETFSDADQLRDINTP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
ESMLMSKQIAQTVNAAMALLPEELRTAITLREIEGLSYEEIAEMMGCPIGTVRSRIFRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHH
EAIAAKLRPLLDTPEGRRW
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]