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The map label for this gene is livK [C]

Identifier: 237813163

GI number: 237813163

Start: 2854429

End: 2855577

Strand: Direct

Name: livK [C]

Synonym: GBP346_A2926

Alternate gene names: 237813163

Gene position: 2854429-2855577 (Clockwise)

Preceding gene: 237813162

Following gene: 237813165

Centisome position: 69.64

GC content: 67.62

Gene sequence:

>1149_bases
ATGAGACTCCGCTCGTCACTGCCCTCCCTCGCCCTCGCCGCGGCATTCGCGTGCGGCGCAACCGGCGCCGCGCGCGCCGC
CGACGAAACGCCCGTGAGGATCGGCTTCGCCGCGCCGCTCACGGGCGTCAACGCGGGCTACGGCAAGGATCTGCAAAACG
GCGTGCAGCTCGCGCTCGACGACGCCCGCGCGCAAAAGATCACGATCGCCGGCAAGCCCGCGCGCTTCGAACTCGTCGTC
GAGGACGACCAGGCCGATCCGCGGATCGGCGTGCAGGCCGCGCAGAGCCTCGTCGACAAGAAGGTGTCGGTCGTCGTCGG
CCACTTCAACTCCGGCACGACGATTCCGGCGTCGGTCGTCTACGACAAGGCGGGCATCCCCGTCATCGATCCGGCCGCGA
CGAATCCCGTCATCACGTCGCGCGGGCTCGCGAACGTGTTCATGGTGATCGCCACCGACGGCCAGAACGCCGGCAACGCG
GGCCGCTACGCGGTCGACGTGACGAAGGCCAAGCGCATCGCGATCGTCGACGATCGCACCGCGTTCGGCCAGGGCGAAGC
CGACGAGTTCGACAAGGCGGTGAAGGCCGCGGGCGCCGCGATCGTCGCGCGCGAGTACACGAGCAACCAGGCGGTCGACT
TCCGCGCGCAGATCACGAGCCTCAAGAGCAAGAACGTCGATCTGGTCTTCTTCGGCGGCCTCGATTCGCTCGCGGCGAAC
TTCATCAAGCAGATGAAGCAGCTCGGCTTGAACGCGCAGTTCGTCGGCGGCGGCGGCGTGAAGGACGCCGAGTTCATCAA
GATCGCGGGCCCCGCAGCGGAAGGCGCGATGGCGTGGGAATACGGCCGGCCGCTCGACCAGTTGCCGCAAGGCAAGGATT
TCGAGTCGCGCTTCAAGAAGCGCTTCGGCGTCGACGTGCTGTCGTATGCGCAGTTCGGCTATGACGCGACGTGGGCCGCG
ATCAAGGCGATGCAGGCGGCGGGCACGACCGATCCGAGCGGCTATCGGCCCGCGCTGAAGAAGATCGATTTCGAGGGCAT
CACCGGCCGCATCTCGTTCGGCGGCGACGGCTCGCTCAAGAGCGGGATGTCGACGCTCTATCAGGTGAAGAGCGGCGCGT
GGCAGACGATCGTCACGAAGGGGGGCTGA

Upstream 100 bases:

>100_bases
AGCCGGCGCCGCTCCGGCGGCCCGCGACGCGGGCCATGGCGCCGGCCCCGTGCATCCGCGCCACTCGCGTCCCGTTCGTG
CATCGCTACAAGGAAAGAAC

Downstream 100 bases:

>100_bases
CCGGCCGCCCATGTATGGAGCGGACCGCGCGCGACGCGCTGCACGCGCGCGGCCCGGGTCCCGAACGGCGCGCATCGCGC
CCAACCCATGGAGTTTCGAT

Product: putative periplasmic substrate-binding protein

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MRLRSSLPSLALAAAFACGATGAARAADETPVRIGFAAPLTGVNAGYGKDLQNGVQLALDDARAQKITIAGKPARFELVV
EDDQADPRIGVQAAQSLVDKKVSVVVGHFNSGTTIPASVVYDKAGIPVIDPAATNPVITSRGLANVFMVIATDGQNAGNA
GRYAVDVTKAKRIAIVDDRTAFGQGEADEFDKAVKAAGAAIVAREYTSNQAVDFRAQITSLKSKNVDLVFFGGLDSLAAN
FIKQMKQLGLNAQFVGGGGVKDAEFIKIAGPAAEGAMAWEYGRPLDQLPQGKDFESRFKKRFGVDVLSYAQFGYDATWAA
IKAMQAAGTTDPSGYRPALKKIDFEGITGRISFGGDGSLKSGMSTLYQVKSGAWQTIVTKGG

Sequences:

>Translated_382_residues
MRLRSSLPSLALAAAFACGATGAARAADETPVRIGFAAPLTGVNAGYGKDLQNGVQLALDDARAQKITIAGKPARFELVV
EDDQADPRIGVQAAQSLVDKKVSVVVGHFNSGTTIPASVVYDKAGIPVIDPAATNPVITSRGLANVFMVIATDGQNAGNA
GRYAVDVTKAKRIAIVDDRTAFGQGEADEFDKAVKAAGAAIVAREYTSNQAVDFRAQITSLKSKNVDLVFFGGLDSLAAN
FIKQMKQLGLNAQFVGGGGVKDAEFIKIAGPAAEGAMAWEYGRPLDQLPQGKDFESRFKKRFGVDVLSYAQFGYDATWAA
IKAMQAAGTTDPSGYRPALKKIDFEGITGRISFGGDGSLKSGMSTLYQVKSGAWQTIVTKGG
>Mature_382_residues
MRLRSSLPSLALAAAFACGATGAARAADETPVRIGFAAPLTGVNAGYGKDLQNGVQLALDDARAQKITIAGKPARFELVV
EDDQADPRIGVQAAQSLVDKKVSVVVGHFNSGTTIPASVVYDKAGIPVIDPAATNPVITSRGLANVFMVIATDGQNAGNA
GRYAVDVTKAKRIAIVDDRTAFGQGEADEFDKAVKAAGAAIVAREYTSNQAVDFRAQITSLKSKNVDLVFFGGLDSLAAN
FIKQMKQLGLNAQFVGGGGVKDAEFIKIAGPAAEGAMAWEYGRPLDQLPQGKDFESRFKKRFGVDVLSYAQFGYDATWAA
IKAMQAAGTTDPSGYRPALKKIDFEGITGRISFGGDGSLKSGMSTLYQVKSGAWQTIVTKGG

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=349, Percent_Identity=30.0859598853868, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI48994941, Length=351, Percent_Identity=29.0598290598291, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 39996; Mature: 39996

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRSSLPSLALAAAFACGATGAARAADETPVRIGFAAPLTGVNAGYGKDLQNGVQLALD
CCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCEEEEE
DARAQKITIAGKPARFELVVEDDQADPRIGVQAAQSLVDKKVSVVVGHFNSGTTIPASVV
CCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHEE
YDKAGIPVIDPAATNPVITSRGLANVFMVIATDGQNAGNAGRYAVDVTKAKRIAIVDDRT
ECCCCCCEECCCCCCCCEECCCCCEEEEEEEECCCCCCCCCCEEEEEECCCEEEEEECCC
AFGQGEADEFDKAVKAAGAAIVAREYTSNQAVDFRAQITSLKSKNVDLVFFGGLDSLAAN
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHCCCCCCEEEECCHHHHHHH
FIKQMKQLGLNAQFVGGGGVKDAEFIKIAGPAAEGAMAWEYGRPLDQLPQGKDFESRFKK
HHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCEEECCCCCHHHCCCCCCHHHHHHH
RFGVDVLSYAQFGYDATWAAIKAMQAAGTTDPSGYRPALKKIDFEGITGRISFGGDGSLK
HHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCHH
SGMSTLYQVKSGAWQTIVTKGG
HHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure
MRLRSSLPSLALAAAFACGATGAARAADETPVRIGFAAPLTGVNAGYGKDLQNGVQLALD
CCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCEEEEE
DARAQKITIAGKPARFELVVEDDQADPRIGVQAAQSLVDKKVSVVVGHFNSGTTIPASVV
CCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHEE
YDKAGIPVIDPAATNPVITSRGLANVFMVIATDGQNAGNAGRYAVDVTKAKRIAIVDDRT
ECCCCCCEECCCCCCCCEECCCCCEEEEEEEECCCCCCCCCCEEEEEECCCEEEEEECCC
AFGQGEADEFDKAVKAAGAAIVAREYTSNQAVDFRAQITSLKSKNVDLVFFGGLDSLAAN
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHCCCCCCEEEECCHHHHHHH
FIKQMKQLGLNAQFVGGGGVKDAEFIKIAGPAAEGAMAWEYGRPLDQLPQGKDFESRFKK
HHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCEEECCCCCHHHCCCCCCHHHHHHH
RFGVDVLSYAQFGYDATWAAIKAMQAAGTTDPSGYRPALKKIDFEGITGRISFGGDGSLK
HHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCHH
SGMSTLYQVKSGAWQTIVTKGG
HHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA