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The map label for this gene is argD [H]

Identifier: 237813145

GI number: 237813145

Start: 2834758

End: 2835990

Strand: Reverse

Name: argD [H]

Synonym: GBP346_A2907

Alternate gene names: 237813145

Gene position: 2835990-2834758 (Counterclockwise)

Preceding gene: 237813147

Following gene: 237813144

Centisome position: 69.19

GC content: 68.13

Gene sequence:

>1233_bases
ATGAAGAGCCCGAACGTGTCCCGTCAGACTTTCGATGAAGTGATGGTGCCGGTGTTTTCCCCCGCGCCGTTCATCCCCGA
TCGCGGCGAAGGCTCGCGCGTCTGGGACACGGAAGGCCGCGATTATGTCGATTTCGCCGGCGGCATCGCCGTCACCGCGC
TCGGCCACGGTCATCCGGAGCTCCTCAAGGTGCTCGACGAGCAAAGCCGCAAGCTCTGGCACATCGGCAACGGCTACACG
AACGAGCCCGTGCTGCGCCTCGCGAAGCGCCTGGAATCGCTCACGTTCGCCGACCGCGCGTTCTTCGCGAACTCCGGCGC
CGAAGCCAACGAGGCCGCCCTCAAGCTCGCGCGCCGCGTCGCGTTCGAACGCCACGGCGCCGACAAGTACGAAATCGTGT
CGTTCCTGCAGTCGTTCCACGGCCGCACGTTCTTCACCGTGAGCGTCGGCGGCCAATCGAAGTACTCCGAAGGTTTCGGT
CCGGTGCCCGAAGGCATCAAGCATCTGCCGTTCAACGACATCGCCGCCGCCCAGGCCGCGATCGGCCCGAAGACCTGCGC
GGTCATCGTCGAGCCGATCCAGGGCGAGGGCGGCGTGATTCCCGCCGATCCCGCCTTCCTCAAGGCGCTGCGCGAAGCGT
GCGACGCGCACGGCGCGCTCCTCATCTTCGACGAGGTGCAAACGGGCGTCGGCCGCACCGGCCACTTCTACGCGTACATG
GACACGGGCGTCACGCCCGACATCCTGACCACCGCGAAGGCGCTCGGCAACGGCTTGCCGATCGGCGCGATGCTCACCAC
CGAGGCGCTCGCCGCGCACTTCAAGGTCGGCGTGCACGGCACGACGTACGGCGGCAATCCGCTCGCGTCGGCGATCGCCG
AGAAGGTCGTCGAGCTCGTCGGCGATCCCGCGCTGCTCGAGGGCGTCAAGCAACGCAGCGCGCGCCTCACGGCCACGCTC
GAGAAGATCAACGCGCGCTTCAAGCTCTTCAAGGAGATTCGCGGCAAGGGCCTGCTGATCGGCGCCGAGCTCGTCGGCGC
GCTCGACGGCCGCGCGAAGGACTTCGTGTCGGCCGCGGCCGAGCACGGCGTCATCATGCTGATCGCCGGCCCGAACGTGC
TGCGCTTCGCGCCGTCGCTCGTGATTCCGCTCGACGTGCTCGACGAGGGCCTCGCGCGCTTCGAGAAGGCGGTCGAGCAG
GTGCTCGCGCAAGCCGAAGCCGCGTCGCGCTAA

Upstream 100 bases:

>100_bases
GAACCCCGTCCGATAAATCCCGTCGCAATTGCGCAAGACGCATCCCGCGCCGTTGCCTAAACTTGAACGTGTTACCTGTT
ACGAAACGAAAGGAATCGTC

Downstream 100 bases:

>100_bases
GCCGGCCCGAACCGCCCCCATCGCTGACGTAGACAGGAACGACGATGCTCTTCGTACGCCCCGGCAGACTCACCGATCTC
GACGCGCTCGCGCAGATGGC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKSPNVSRQTFDEVMVPVFSPAPFIPDRGEGSRVWDTEGRDYVDFAGGIAVTALGHGHPELLKVLDEQSRKLWHIGNGYT
NEPVLRLAKRLESLTFADRAFFANSGAEANEAALKLARRVAFERHGADKYEIVSFLQSFHGRTFFTVSVGGQSKYSEGFG
PVPEGIKHLPFNDIAAAQAAIGPKTCAVIVEPIQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGHFYAYM
DTGVTPDILTTAKALGNGLPIGAMLTTEALAAHFKVGVHGTTYGGNPLASAIAEKVVELVGDPALLEGVKQRSARLTATL
EKINARFKLFKEIRGKGLLIGAELVGALDGRAKDFVSAAAEHGVIMLIAGPNVLRFAPSLVIPLDVLDEGLARFEKAVEQ
VLAQAEAASR

Sequences:

>Translated_410_residues
MKSPNVSRQTFDEVMVPVFSPAPFIPDRGEGSRVWDTEGRDYVDFAGGIAVTALGHGHPELLKVLDEQSRKLWHIGNGYT
NEPVLRLAKRLESLTFADRAFFANSGAEANEAALKLARRVAFERHGADKYEIVSFLQSFHGRTFFTVSVGGQSKYSEGFG
PVPEGIKHLPFNDIAAAQAAIGPKTCAVIVEPIQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGHFYAYM
DTGVTPDILTTAKALGNGLPIGAMLTTEALAAHFKVGVHGTTYGGNPLASAIAEKVVELVGDPALLEGVKQRSARLTATL
EKINARFKLFKEIRGKGLLIGAELVGALDGRAKDFVSAAAEHGVIMLIAGPNVLRFAPSLVIPLDVLDEGLARFEKAVEQ
VLAQAEAASR
>Mature_410_residues
MKSPNVSRQTFDEVMVPVFSPAPFIPDRGEGSRVWDTEGRDYVDFAGGIAVTALGHGHPELLKVLDEQSRKLWHIGNGYT
NEPVLRLAKRLESLTFADRAFFANSGAEANEAALKLARRVAFERHGADKYEIVSFLQSFHGRTFFTVSVGGQSKYSEGFG
PVPEGIKHLPFNDIAAAQAAIGPKTCAVIVEPIQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGHFYAYM
DTGVTPDILTTAKALGNGLPIGAMLTTEALAAHFKVGVHGTTYGGNPLASAIAEKVVELVGDPALLEGVKQRSARLTATL
EKINARFKLFKEIRGKGLLIGAELVGALDGRAKDFVSAAAEHGVIMLIAGPNVLRFAPSLVIPLDVLDEGLARFEKAVEQ
VLAQAEAASR

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=34.375, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI13994255, Length=439, Percent_Identity=29.3849658314351, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=36.4548494983278, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI37574042, Length=426, Percent_Identity=28.4037558685446, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=28.9002557544757, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442705, Length=426, Percent_Identity=27.9342723004695, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=26.4705882352941, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI188536080, Length=435, Percent_Identity=23.2183908045977, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI38679950, Length=435, Percent_Identity=23.2183908045977, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI38679946, Length=435, Percent_Identity=23.2183908045977, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788044, Length=407, Percent_Identity=60.9336609336609, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=57.6826196473552, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1789016, Length=412, Percent_Identity=33.495145631068, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI145693181, Length=394, Percent_Identity=33.756345177665, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1787560, Length=409, Percent_Identity=32.518337408313, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1786991, Length=295, Percent_Identity=32.2033898305085, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=30.8917197452229, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=383, Percent_Identity=34.4647519582245, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=30.045871559633, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=258, Percent_Identity=34.1085271317829, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=434, Percent_Identity=27.1889400921659, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71981843, Length=178, Percent_Identity=32.5842696629214, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=432, Percent_Identity=26.6203703703704, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=398, Percent_Identity=39.9497487437186, Blast_Score=280, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.0845771144279, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=28.6624203821656, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=374, Percent_Identity=26.2032085561497, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357415, Length=384, Percent_Identity=32.03125, Blast_Score=198, Evalue=5e-51,
Organism=Drosophila melanogaster, GI28574759, Length=413, Percent_Identity=30.9927360774818, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=29.6127562642369, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=29.2161520190024, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281366494, Length=437, Percent_Identity=25.1716247139588, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24667139, Length=437, Percent_Identity=25.1716247139588, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24667143, Length=437, Percent_Identity=25.1716247139588, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43706; Mature: 43706

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSPNVSRQTFDEVMVPVFSPAPFIPDRGEGSRVWDTEGRDYVDFAGGIAVTALGHGHPE
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCHHHHCCCEEEEEECCCCHH
LLKVLDEQSRKLWHIGNGYTNEPVLRLAKRLESLTFADRAFFANSGAEANEAALKLARRV
HHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AFERHGADKYEIVSFLQSFHGRTFFTVSVGGQSKYSEGFGPVPEGIKHLPFNDIAAAQAA
HHHHCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHH
IGPKTCAVIVEPIQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGHFYAYM
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEE
DTGVTPDILTTAKALGNGLPIGAMLTTEALAAHFKVGVHGTTYGGNPLASAIAEKVVELV
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHH
GDPALLEGVKQRSARLTATLEKINARFKLFKEIRGKGLLIGAELVGALDGRAKDFVSAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCHHHHHHHHHH
EHGVIMLIAGPNVLRFAPSLVIPLDVLDEGLARFEKAVEQVLAQAEAASR
HCCEEEEEECCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSPNVSRQTFDEVMVPVFSPAPFIPDRGEGSRVWDTEGRDYVDFAGGIAVTALGHGHPE
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCHHHHCCCEEEEEECCCCHH
LLKVLDEQSRKLWHIGNGYTNEPVLRLAKRLESLTFADRAFFANSGAEANEAALKLARRV
HHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AFERHGADKYEIVSFLQSFHGRTFFTVSVGGQSKYSEGFGPVPEGIKHLPFNDIAAAQAA
HHHHCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHH
IGPKTCAVIVEPIQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGHFYAYM
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEE
DTGVTPDILTTAKALGNGLPIGAMLTTEALAAHFKVGVHGTTYGGNPLASAIAEKVVELV
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHH
GDPALLEGVKQRSARLTATLEKINARFKLFKEIRGKGLLIGAELVGALDGRAKDFVSAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCHHHHHHHHHH
EHGVIMLIAGPNVLRFAPSLVIPLDVLDEGLARFEKAVEQVLAQAEAASR
HCCEEEEEECCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]