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The map label for this gene is tcp [H]

Identifier: 237813115

GI number: 237813115

Start: 2809483

End: 2811405

Strand: Reverse

Name: tcp [H]

Synonym: GBP346_A2877

Alternate gene names: 237813115

Gene position: 2811405-2809483 (Counterclockwise)

Preceding gene: 237813119

Following gene: 237813114

Centisome position: 68.59

GC content: 68.95

Gene sequence:

>1923_bases
ATGAGCAAGCATGTATTTGGACCGGGTATGCGCCTGATGGCGCGCATGAAGCTGCCCAGGAAGCTCGTGATTCTCGCCGC
GCTGTTCATCGTGCCGCTCGTCGCCGCGCTCTATGCGACGCTCGCCGTCGCCTGGCACGCTTATGCGACGACGCAGGGCG
AGCGCGACGGCATCTCGATCCTCGAAACGACACAGGATTTGTTGAAGGCGGTGCAGGTACGGCGCGGCGCGGGCGCTTCG
GTGCTCGCGGGCAACGAAGCAATGCGCGCGAAGTTCGACGCGGCGAGCGCGAGCGCCGGCCGTCTCGCGGCGACGCTCAA
GCAGCAGGTGCGCGGCACCGACCGGTTCGACATCGTCGCGGCGGTGGACGCGCTCGCGAGCGAATACGGCAAGGTGGCGG
CGGGCGGACTCGGCACGTCCGCGGCCGCGCTGTTCGGTTCGCACACCGACGTGATCCATGCGATCTTCCTGTTCGAGAAG
GATCTCGCGGTGGCGTCGCGGCTCGGCGTCGATCCGGACGCATCGAACTATCACCTGATCGATTCGGTGCTGTTCGTGCT
GCCGGGGACGGCCGAAACGGTCGGCGTGCTGCGCGGCAAGGGCGCCGCCGCGCTTGTGGGCGGCGCGCTCGGCGAGGCCG
ACAAGCGCGAGCTCGCGGTGCGCGCGGGCAGTCTCGCCGAACAGATGAGCGTGATTCGCCATCATCTCGACCGCATGAAG
GACCGGCTCGGCGCGGGCGTGCCGGACGGCGTCGATCTCGGCGCGGTGGCGGCGTTTCAACGCGCGGCGGCCGCGCTCGC
GGGCGGCGACGCGTCGATCGACGCGAAGACCTATTTCCAGCGGGGCACCGATGCGATCGACGCGCTGTATCGCGTGCACG
GCACGCTCGCGCAACAATTGCGCGAGCGCCTCGCGGCGCGCGCGCATGCCGAACAGGTGAAGGTGGCCGCGATCCTCGCC
CTGAGTGTCGTGCTTGTCGCCTGCGCGCTCTATCTTTTCGTCGCCTTCGCGATGTCGACGCACGAGGACGTCGCGCAACT
GTCCGACTGCATGCGCGCGGTGGGCGACGGCGATCTGCGCGCGCGCCTCGCGGTGCGCGGCGGCGACGAATTCGCGTTCA
TCAAGCGCGGCTTCAACGCGCTGCTCGACGTCTGGGCGCAGACGCTGACCGAGACGCGGCGCGTCGCCGATTCGGTGATG
GTCGGCAGCCAGCAGATCGCCGCCGGCAACCTCGATCTGTCGGGGCGCACCGAGACGCAGGCGGCATCGCTCGAGCAAAC
GGCGGCGAGCATGGAAGAGCTGACGTCGACGGTGCGCCATAACGCGTCGAACGCATCGCACGCGAGCACGCTGAGCGCCG
AGGCGTCCGAGCGCGCGGCGGACACCGGCCGGATCGTGACGCATGCGGTATCGCTGATGACGCGGATTCACGACAGTTCG
AACCGGATGGCGGAGATCGTGACGGTGATCGAGGGCATCGCGTTCCAGACCAACATCCTCGCGCTGAACGCGGCCGTCGA
GGCCGCGCGCGCGGGCGAGCAGGGCAAGGGCTTCGCGGTCGTCGCGGGCGAGGTGCGCGCGCTCGCGCACCGCAGCGCGA
CCGCCGCGAAGGACGTGAAGGAGCTGATTCACGAATCGATTCGGCACGTGACCGACGGCTCGTCGCTGTTTCAGCGCGCG
GACGATGCGATCCGCAGCGTGAACGCGTCGATCAAGAGCGTCGATACCGTCGTCAGCGAGATCGCGAAGGCGTCCGAGCA
GCAAAGCGACGGGATCGAGCAGGTCAACGCGGCGATCACGCAGATGGACGAAGTGACGCAGCGCAACGCGGCGCTCGTCG
AGGAATCGGCTGCCGCGAGCGCGTCGCTGCGCGAGCAGGCCGAGCATATGGGCAAGCTCGTCGGGCGCTTCGTGCTCGCG
TAG

Upstream 100 bases:

>100_bases
CGTGATCGGATGATTGATCTTGCTTAAGTATCGGGCCGAACGATCCGTATACGGAAAGGCGGCCGTAAAGGTCGTCTCAT
CACATCGAAAAGGGGCAAGA

Downstream 100 bases:

>100_bases
CGGGCGGGCAGCCCTTCAGCGTATACGCGCGCCGCCCGTTCGGCGGCAAGCGCGCGGCGTCGGAGGTTGATTTGCATCAA
GTCCGTCCGGGCCGCGCGCC

Product: methyl-accepting chemotaxis protein I

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MSKHVFGPGMRLMARMKLPRKLVILAALFIVPLVAALYATLAVAWHAYATTQGERDGISILETTQDLLKAVQVRRGAGAS
VLAGNEAMRAKFDAASASAGRLAATLKQQVRGTDRFDIVAAVDALASEYGKVAAGGLGTSAAALFGSHTDVIHAIFLFEK
DLAVASRLGVDPDASNYHLIDSVLFVLPGTAETVGVLRGKGAAALVGGALGEADKRELAVRAGSLAEQMSVIRHHLDRMK
DRLGAGVPDGVDLGAVAAFQRAAAALAGGDASIDAKTYFQRGTDAIDALYRVHGTLAQQLRERLAARAHAEQVKVAAILA
LSVVLVACALYLFVAFAMSTHEDVAQLSDCMRAVGDGDLRARLAVRGGDEFAFIKRGFNALLDVWAQTLTETRRVADSVM
VGSQQIAAGNLDLSGRTETQAASLEQTAASMEELTSTVRHNASNASHASTLSAEASERAADTGRIVTHAVSLMTRIHDSS
NRMAEIVTVIEGIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRALAHRSATAAKDVKELIHESIRHVTDGSSLFQRA
DDAIRSVNASIKSVDTVVSEIAKASEQQSDGIEQVNAAITQMDEVTQRNAALVEESAAASASLREQAEHMGKLVGRFVLA

Sequences:

>Translated_640_residues
MSKHVFGPGMRLMARMKLPRKLVILAALFIVPLVAALYATLAVAWHAYATTQGERDGISILETTQDLLKAVQVRRGAGAS
VLAGNEAMRAKFDAASASAGRLAATLKQQVRGTDRFDIVAAVDALASEYGKVAAGGLGTSAAALFGSHTDVIHAIFLFEK
DLAVASRLGVDPDASNYHLIDSVLFVLPGTAETVGVLRGKGAAALVGGALGEADKRELAVRAGSLAEQMSVIRHHLDRMK
DRLGAGVPDGVDLGAVAAFQRAAAALAGGDASIDAKTYFQRGTDAIDALYRVHGTLAQQLRERLAARAHAEQVKVAAILA
LSVVLVACALYLFVAFAMSTHEDVAQLSDCMRAVGDGDLRARLAVRGGDEFAFIKRGFNALLDVWAQTLTETRRVADSVM
VGSQQIAAGNLDLSGRTETQAASLEQTAASMEELTSTVRHNASNASHASTLSAEASERAADTGRIVTHAVSLMTRIHDSS
NRMAEIVTVIEGIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRALAHRSATAAKDVKELIHESIRHVTDGSSLFQRA
DDAIRSVNASIKSVDTVVSEIAKASEQQSDGIEQVNAAITQMDEVTQRNAALVEESAAASASLREQAEHMGKLVGRFVLA
>Mature_639_residues
SKHVFGPGMRLMARMKLPRKLVILAALFIVPLVAALYATLAVAWHAYATTQGERDGISILETTQDLLKAVQVRRGAGASV
LAGNEAMRAKFDAASASAGRLAATLKQQVRGTDRFDIVAAVDALASEYGKVAAGGLGTSAAALFGSHTDVIHAIFLFEKD
LAVASRLGVDPDASNYHLIDSVLFVLPGTAETVGVLRGKGAAALVGGALGEADKRELAVRAGSLAEQMSVIRHHLDRMKD
RLGAGVPDGVDLGAVAAFQRAAAALAGGDASIDAKTYFQRGTDAIDALYRVHGTLAQQLRERLAARAHAEQVKVAAILAL
SVVLVACALYLFVAFAMSTHEDVAQLSDCMRAVGDGDLRARLAVRGGDEFAFIKRGFNALLDVWAQTLTETRRVADSVMV
GSQQIAAGNLDLSGRTETQAASLEQTAASMEELTSTVRHNASNASHASTLSAEASERAADTGRIVTHAVSLMTRIHDSSN
RMAEIVTVIEGIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRALAHRSATAAKDVKELIHESIRHVTDGSSLFQRAD
DAIRSVNASIKSVDTVVSEIAKASEQQSDGIEQVNAAITQMDEVTQRNAALVEESAAASASLREQAEHMGKLVGRFVLA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=357, Percent_Identity=43.4173669467787, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1788194, Length=329, Percent_Identity=45.5927051671732, Blast_Score=247, Evalue=2e-66,
Organism=Escherichia coli, GI1788195, Length=263, Percent_Identity=49.8098859315589, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI2367378, Length=292, Percent_Identity=45.5479452054795, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI1789453, Length=311, Percent_Identity=36.6559485530547, Blast_Score=180, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 67210; Mature: 67079

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHVFGPGMRLMARMKLPRKLVILAALFIVPLVAALYATLAVAWHAYATTQGERDGISI
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LETTQDLLKAVQVRRGAGASVLAGNEAMRAKFDAASASAGRLAATLKQQVRGTDRFDIVA
HHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHH
AVDALASEYGKVAAGGLGTSAAALFGSHTDVIHAIFLFEKDLAVASRLGVDPDASNYHLI
HHHHHHHHHCCHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
DSVLFVLPGTAETVGVLRGKGAAALVGGALGEADKRELAVRAGSLAEQMSVIRHHLDRMK
HHHHHHCCCCHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLGAGVPDGVDLGAVAAFQRAAAALAGGDASIDAKTYFQRGTDAIDALYRVHGTLAQQL
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
RERLAARAHAEQVKVAAILALSVVLVACALYLFVAFAMSTHEDVAQLSDCMRAVGDGDLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ARLAVRGGDEFAFIKRGFNALLDVWAQTLTETRRVADSVMVGSQQIAAGNLDLSGRTETQ
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHH
AASLEQTAASMEELTSTVRHNASNASHASTLSAEASERAADTGRIVTHAVSLMTRIHDSS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NRMAEIVTVIEGIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRALAHRSATAAKDVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
ELIHESIRHVTDGSSLFQRADDAIRSVNASIKSVDTVVSEIAKASEQQSDGIEQVNAAIT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QMDEVTQRNAALVEESAAASASLREQAEHMGKLVGRFVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKHVFGPGMRLMARMKLPRKLVILAALFIVPLVAALYATLAVAWHAYATTQGERDGISI
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LETTQDLLKAVQVRRGAGASVLAGNEAMRAKFDAASASAGRLAATLKQQVRGTDRFDIVA
HHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHH
AVDALASEYGKVAAGGLGTSAAALFGSHTDVIHAIFLFEKDLAVASRLGVDPDASNYHLI
HHHHHHHHHCCHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
DSVLFVLPGTAETVGVLRGKGAAALVGGALGEADKRELAVRAGSLAEQMSVIRHHLDRMK
HHHHHHCCCCHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLGAGVPDGVDLGAVAAFQRAAAALAGGDASIDAKTYFQRGTDAIDALYRVHGTLAQQL
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
RERLAARAHAEQVKVAAILALSVVLVACALYLFVAFAMSTHEDVAQLSDCMRAVGDGDLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ARLAVRGGDEFAFIKRGFNALLDVWAQTLTETRRVADSVMVGSQQIAAGNLDLSGRTETQ
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHH
AASLEQTAASMEELTSTVRHNASNASHASTLSAEASERAADTGRIVTHAVSLMTRIHDSS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NRMAEIVTVIEGIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRALAHRSATAAKDVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
ELIHESIRHVTDGSSLFQRADDAIRSVNASIKSVDTVVSEIAKASEQQSDGIEQVNAAIT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QMDEVTQRNAALVEESAAASASLREQAEHMGKLVGRFVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]