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The map label for this gene is nrdD [C]

Identifier: 237813102

GI number: 237813102

Start: 2798416

End: 2800179

Strand: Direct

Name: nrdD [C]

Synonym: GBP346_A2864

Alternate gene names: 237813102

Gene position: 2798416-2800179 (Clockwise)

Preceding gene: 237813101

Following gene: 237813103

Centisome position: 68.28

GC content: 64.57

Gene sequence:

>1764_bases
TTGTCCGAGACCATGCACCCTTGCGCCGCGCCGAATCCCGCGTCGCGCGACAAGCCGTTGATCGACGTCGAATCGTCGAT
CAACGAATACCTGGACCGGCAGGACTGGCGCGTCAACGCGAACGCGAACCAGGGCTATTCGCTCGGCGGCCTGATCCTGA
ACGTGTCCGGCAAGGTGATCGCGAACTACTGGCTGAGCCACGTCTACCCGAGCGCGATCGGCGAAGCGCACCGCAATGCG
GATCTGCACATCCACGATCTCGACGTGCTGTCCGGCTACTGCGCGGGCTGGTCGCTGCGCACGCTGCTCAACGAAGGGTT
GAACGGCGTGCCCGGCAAGGTCGAGTCGGGGCCGCCGAAGCACATGTCGAGCGCGGTCGGCCAGATCGTGAACTTCCTCG
GCACGCTGCAGAACGAATGGGCGGGCGCGCAGGCGTTCAGCTCGTTCGACACGTACATGGCGCCGTTCGTGCGCCGCGAC
GCGCTCACCTACGCCGAAGTGCGCCAGTCCGTCCAGGAACTGATCTACAACCTGAACGTGCCGTCACGCTGGGGCACGCA
GACGCCGTTCACGAACCTGACGTTCGACTGGATCTGCCCCGAGGATCTGCGCGAGCAAGTGCCCGTGATCGCCGGCGAAG
AGATGCCGTTCACGTACGGCGATCTGCAGCCCGAAATGGACATGATCAACCAGGCGTACATCGAGGTGATGCAGGCGGGC
GACGCGGCGGGCCGCGTGTTCACGTTCCCGATTCCGACCTACAACATCACCGCCGATTTCGACTGGCACAGCCCGAACGC
CGAGCGCCTGTTCGAGATGACCGCGCGCTACGGCCTGCCGTACTTTCAGAACTTCATCAATTCCGAGTTGAAGCCGAACA
TGATCCGCTCGATGTGCTGCCGGCTGCAGCTCGACCTGCGCGAGCTGATGAAGCGCGGCAACGGGCTGTTCGGCTCGGCC
GAGCAGACGGGATCGATCGGCGTGGTCACCGTGAATTGCGCGCGGCTCGGCTATCTGCACGCGGGCGACGAGCGCGCGCT
CTTCGCGCGGCTCGACACGCTGCTCGACTACGGCAAGGAAAGCCTCGAGATCAAGCGCGAGGTGATCCAGCATCACATGA
ACAACGGGCTCTTCCCGTACACGAAGCGCTATCTCGGCACGCTGCGCAATCATTTCTCGACGCTCGGCGTGAACGGCATC
AACGAGATGATCCGCAATTTCACGCGCGACGCGCACGATCTGACGACCGACTGGGGCCACGCGTTCGCGCTGCGCCTGCT
CGACCACGTGCGCGCGCGCATCGTCGAGTATCAGGAGGAAACGGGCCACATGTACAACCTCGAGGCGACGCCGGCCGAGG
GCACGACGTACCGCTTCGCGAAGGAAGACCGCCGCCGCTATCCGGACATCCTGCAGGCGGGCACGCCGCAGATGCCGTAC
TACACGAACTCGTCGCAGTTGCCGGTGGGCTTCACCGACGATCCGTTCGAGGCGCTCGAACGCCAGGACGACCTGCAGCG
CAAATACACGGGCGGCACGGTGCTGCATCTGTACATGACCGAGCCGCTGTCGTCCGCCGACGCGTGCCGCACGCTCGTGA
AGCGCGCGCTCACCCGCTTCTCGCTGCCGTATCTGACCGTCACGCCGACCTTCTCGATCTGCCCGACGCACGGCTATCTC
GCCGGCAGCCACCCGTTTTGCCCGAAGTGCGACGAAGCGCTGCTGCGTCGCAAATTGTCTCAATCCCAACCGATGGAAGC
CTGA

Upstream 100 bases:

>100_bases
CGCGTCAAACTTCGCCGGATCGCCGTTGACCCATACAACATCTGGTATTTAGCATTCACCCCGTCACCAGATTTTGTGCC
ACCAACGAGAGAGGCCCACG

Downstream 100 bases:

>100_bases
ACATGACGACGACATTGCAAGCCAACCCACAAGCCGCCCGCGCCGCGATCGTGCTGTCCGACGACGAGCGCCAGCCGTGC
GAGATCTGGACCCGCGTGAT

Product: anaerobic ribonucleoside triphosphate reductase

Products: dUTP; H2O; Oxidized thioredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 586

Protein sequence:

>587_residues
MSETMHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPSAIGEAHRNA
DLHIHDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRD
ALTYAEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAG
DAAGRVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMKRGNGLFGSA
EQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGI
NEMIRNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPY
YTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTFSICPTHGYL
AGSHPFCPKCDEALLRRKLSQSQPMEA

Sequences:

>Translated_587_residues
MSETMHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPSAIGEAHRNA
DLHIHDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRD
ALTYAEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAG
DAAGRVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMKRGNGLFGSA
EQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGI
NEMIRNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPY
YTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTFSICPTHGYL
AGSHPFCPKCDEALLRRKLSQSQPMEA
>Mature_586_residues
SETMHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPSAIGEAHRNAD
LHIHDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDA
LTYAEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAGD
AAGRVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMKRGNGLFGSAE
QTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGIN
EMIRNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPYY
TNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTFSICPTHGYLA
GSHPFCPKCDEALLRRKLSQSQPMEA

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2 [C]

Molecular weight: Translated: 66321; Mature: 66189

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETMHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVI
CCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEECCCCCCCEECCEEEECCCHHH
ANYWLSHVYPSAIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPK
HHHHHHHHCHHHHHHHHCCCCCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHH
HMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTYAEVRQSVQELIYNLNV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAG
CCCCCCCCCCCCCEEECCCCHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCC
DAAGRVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCC
CCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHH
RLQLDLRELMKRGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKE
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHCCEEECCCCHHHHHHHHHHHHCCHH
SLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMIRNFTRDAHDLTTDWGH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHCHHHH
AFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPY
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCHHHHHCCCCCCCE
YTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRF
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
SLPYLTVTPTFSICPTHGYLAGSHPFCPKCDEALLRRKLSQSQPMEA
CCCEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SETMHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVI
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEECCCCCCCEECCEEEECCCHHH
ANYWLSHVYPSAIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPK
HHHHHHHHCHHHHHHHHCCCCCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHH
HMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTYAEVRQSVQELIYNLNV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAG
CCCCCCCCCCCCCEEECCCCHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCC
DAAGRVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCC
CCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHH
RLQLDLRELMKRGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKE
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHCCEEECCCCHHHHHHHHHHHHCCHH
SLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMIRNFTRDAHDLTTDWGH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHCHHHH
AFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPY
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCHHHHHCCCCCCCE
YTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRF
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
SLPYLTVTPTFSICPTHGYLAGSHPFCPKCDEALLRRKLSQSQPMEA
CCCEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Reduced thioredoxin; UTP [C]

Specific reaction: Reduced thioredoxin + UTP --> dUTP + H2O + Oxidized thioredoxin [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]