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The map label for this gene is argM [C]

Identifier: 237813072

GI number: 237813072

Start: 2769724

End: 2771151

Strand: Reverse

Name: argM [C]

Synonym: GBP346_A2834

Alternate gene names: 237813072

Gene position: 2771151-2769724 (Counterclockwise)

Preceding gene: 237813073

Following gene: 237813071

Centisome position: 67.61

GC content: 67.58

Gene sequence:

>1428_bases
GTGACGTATCGAACCGAAGACATCGCCTATGTAGCGCCGCTGCACGCGAGCGCCGCGCCCGCGCACCGCACGAGCGCCGA
ATACCGCGCGCTCGACGCCGCGCACCACCTCCACCCGTTCTCGGACATGGGCTCGCTCAATCGCGCGGGCAGCCGCGTGA
TCGTGAAGGCCGAAGGCGTCCACCTGTGGGATTCCGACGGCAACAGGATCATCGACGGCATGGCCGGGCTCTGGTGCGTG
AACGTCGGCTACGGCCGCGACGAACTGATCGAGGCCGGCAGCCGCCAGTTGCGCGAGCTGCCGTTCTACAACACCTTCTT
CAAGACCACCCATCCGCCCGTCATCGAGCTGTCCGCGCTGCTCGCGCAGATCGCGCCGCCCGCGTTCAACCGCTTCTTCT
ATTGCAACAGCGGCTCCGAGGGCAACGACACGGTGCTGCGCATCGCGCATCAGTACTGGCGCGCGCAGAACCGCCCGCAG
AAGAAGTTCGTCATTTCGCGCCGAAACGGCTACCACGGCTCGACGATCGCGGGCGCGACGCTCGGCGGCATGGGCTACAT
GCACGAGCAGATGCCCTCGAAGGTCGAGCACATCGTCCACATCGATCAGCCCTATTACTTCGGCGAAGCGCGCGAGGGGC
AGACGCCCGAGGCGTTCGGCCTCGAGCGCGCGCGACAGCTCGAAGCGAAGATTCTCGAGCTCGGCGCGCAGAACGTCGCG
GCGTTCATCGGCGAGCCGTTCCAGGGCGCGGGCGGCGTGATCTTTCCGCCGTCGACGTACTGGCCGGAGATCGAGCGGAT
CTGCCGCCAGTACGACGTGCTGCTCGTCGCCGACGAAGTGATCGGCGGCTTCGGGCGCACCGGCGAATGGTTCGCGCACC
AGCACTTCGGCTTCGCGCCCGACCTGATGACGCTCGCCAAGGGCCTGACGAGCGGTTACGTGCCGATGGGCGCGGTCGCG
CTGTCGGACCGGATCGCCGACGCGCTGATCGCGCACGGCGAGTTCAACCACGGGATGACGTACTCCGGGCATCCGGTCGC
GGCGGCGGTGGCCGTCGCGAATCTGAAGGTGCTGCGCGACGAGCGGATCGTCGAGCGCGTGAAGACCGATACCGGCCCCT
ACTTCCAGCAGCGGTTGCGCGAAACGTTCGCGAACCATCCGATCGTCGGCGACATCGCCGGCGCGGGGCTCGTCGCCGGC
ATCCAGCTCGCGCGCGAGCCGCGCACGCGCAAGCGCTTCGAGAACGGCGGCGAAGTCGGCACGATCTGCCGCGACTACTG
CTTCAACGGCAACCTGATCATGCGCGCGACGGGCGACCGGATGCTGCTGTCGCCGCCGCTCGTGATCTCGAAACCGCAGA
TCGACGAGATCGTCGAGAAGGCGAAGCGCGCGATCGATGCGACGGCCAAGCAGTTGGGGTTTGCGTGA

Upstream 100 bases:

>100_bases
GAGTACGAAGCATTTTTCCGCGTGATCAGCTCGTGGGAGCGCAGGCACCTGCTGCTGCACGTTTGAGCGTGCGCACGCAC
GCCGCATTCAGGAGATCCAA

Downstream 100 bases:

>100_bases
TGCGGGGTAGGGGGCGCAGCGGCCTTGTCGGGCATTCTTTTCGTGCGATAGGCGTGGCTTCTATCCACCGTTGCCGCAAT
GCCGCTGATCGAATGCGCTG

Product: putative aminotransferase

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTYRTEDIAYVAPLHASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGVHLWDSDGNRIIDGMAGLWCV
NVGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSALLAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQ
KKFVISRRNGYHGSTIAGATLGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVA
AFIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAPDLMTLAKGLTSGYVPMGAVA
LSDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRDERIVERVKTDTGPYFQQRLRETFANHPIVGDIAGAGLVAG
IQLAREPRTRKRFENGGEVGTICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA

Sequences:

>Translated_475_residues
MTYRTEDIAYVAPLHASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGVHLWDSDGNRIIDGMAGLWCV
NVGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSALLAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQ
KKFVISRRNGYHGSTIAGATLGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVA
AFIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAPDLMTLAKGLTSGYVPMGAVA
LSDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRDERIVERVKTDTGPYFQQRLRETFANHPIVGDIAGAGLVAG
IQLAREPRTRKRFENGGEVGTICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA
>Mature_474_residues
TYRTEDIAYVAPLHASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGVHLWDSDGNRIIDGMAGLWCVN
VGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSALLAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQK
KFVISRRNGYHGSTIAGATLGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVAA
FIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAPDLMTLAKGLTSGYVPMGAVAL
SDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRDERIVERVKTDTGPYFQQRLRETFANHPIVGDIAGAGLVAGI
QLAREPRTRKRFENGGEVGTICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI24119277, Length=360, Percent_Identity=29.1666666666667, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI37574042, Length=370, Percent_Identity=29.7297297297297, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI13994255, Length=423, Percent_Identity=28.1323877068558, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI226442705, Length=365, Percent_Identity=29.3150684931507, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226442709, Length=323, Percent_Identity=30.6501547987616, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI4557809, Length=446, Percent_Identity=27.1300448430493, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI284507298, Length=228, Percent_Identity=32.8947368421053, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI188536080, Length=338, Percent_Identity=26.0355029585799, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI38679950, Length=338, Percent_Identity=26.0355029585799, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI38679946, Length=338, Percent_Identity=26.0355029585799, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1788044, Length=415, Percent_Identity=26.9879518072289, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1786991, Length=447, Percent_Identity=28.8590604026846, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789759, Length=415, Percent_Identity=27.710843373494, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI145693181, Length=411, Percent_Identity=25.7907542579075, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789016, Length=429, Percent_Identity=27.039627039627, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1787560, Length=370, Percent_Identity=29.7297297297297, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786349, Length=307, Percent_Identity=25.7328990228013, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=28.3372365339578, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=423, Percent_Identity=27.6595744680851, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32564660, Length=449, Percent_Identity=29.1759465478842, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=235, Percent_Identity=33.6170212765957, Blast_Score=135, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6323470, Length=462, Percent_Identity=26.4069264069264, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=366, Percent_Identity=30.8743169398907, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=432, Percent_Identity=25.462962962963, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI161085790, Length=426, Percent_Identity=28.8732394366197, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI28574759, Length=430, Percent_Identity=29.3023255813954, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI21357415, Length=442, Percent_Identity=27.6018099547511, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21356575, Length=371, Percent_Identity=29.9191374663073, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI281366494, Length=342, Percent_Identity=23.6842105263158, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24667139, Length=342, Percent_Identity=23.6842105263158, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24667143, Length=342, Percent_Identity=23.6842105263158, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 52347; Mature: 52216

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRTEDIAYVAPLHASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGV
CCCCCCCEEEEECCCCCCCCCHHCCHHHHHHHHHHHCCCCHHHCCHHCCCCEEEEEECCE
HLWDSDGNRIIDGMAGLWCVNVGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSAL
EEECCCCCEEHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHH
LAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQKKFVISRRNGYHGSTIAGAT
HHHHCCCHHCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCHH
LGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVA
HCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHH
AFIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAP
HHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCCCH
DLMTLAKGLTSGYVPMGAVALSDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERIVERVKTDTGPYFQQRLRETFANHPIVGDIAGAGLVAGIQLAREPRTRKRFENGGEVG
HHHHHHHHCCCCHHHHHHHHHHHCCCCCEEHHHCCHHHHHHHHHCCCHHHHHHHCCCCHH
TICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA
HHHHHHHCCCCEEEEECCCEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYRTEDIAYVAPLHASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGV
CCCCCCEEEEECCCCCCCCCHHCCHHHHHHHHHHHCCCCHHHCCHHCCCCEEEEEECCE
HLWDSDGNRIIDGMAGLWCVNVGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSAL
EEECCCCCEEHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHH
LAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQKKFVISRRNGYHGSTIAGAT
HHHHCCCHHCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCHH
LGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVA
HCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHH
AFIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAP
HHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCCCH
DLMTLAKGLTSGYVPMGAVALSDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERIVERVKTDTGPYFQQRLRETFANHPIVGDIAGAGLVAGIQLAREPRTRKRFENGGEVG
HHHHHHHHCCCCHHHHHHHHHHHCCCCCEEHHHCCHHHHHHHHHCCCHHHHHHHCCCCHH
TICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA
HHHHHHHCCCCEEEEECCCEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]