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The map label for this gene is hscB [H]

Identifier: 237813016

GI number: 237813016

Start: 2704148

End: 2704666

Strand: Reverse

Name: hscB [H]

Synonym: GBP346_A2776

Alternate gene names: 237813016

Gene position: 2704666-2704148 (Counterclockwise)

Preceding gene: 237813017

Following gene: 237813015

Centisome position: 65.99

GC content: 68.4

Gene sequence:

>519_bases
TTGAAGGACAGCCACTTCGATCTCTTTCATTTGCCGGCGCGATTCGCGCTCGACGAGCCGACGCTCGACGCCGCGTACCG
CGCCGTGCAGTCGCAGGTGCACCCGGATCGCTTCGCCGCCGCGGGCGACGCGCAAAAGCGCATCGCCATGCAATGGGCGA
CGCGCGCGAACGAGGCATATCAGACGCTGCGCGATCCGCTCAAGCGGGCGACGTACCTGCTGCACCTGCGCGGCGTCGAT
GTCGGCGCGGAGAACAACACGGCGATGGAGCCGGCGTTCCTGATGCAGCAGATGGAGTGGCGCGAGCGCATCGAGGATGC
GGCGGGCGCGAAGAACGTCGACGCGCTCGACGCGCTTCTCGCCGAATTGCGCGACGAGCGGCGCGCGCGCCTCGCGAAGC
TGGGTGCGCTGCTCGACAGCGGCTCGGACCAGGGCGCGGCCGAGGCCGTGCGCCAACTGATGTTCGTCGAGCGCGTATCG
GCCGAGATCGGCGCTCAGATCGAGCGTCTCGAACACTAA

Upstream 100 bases:

>100_bases
CAAGAGGCGGCGCGGGCCGCCTTTTTAATGGGCGGCACTTCGGTCGACGTGCCGCGGTCGACAACGAGTTGAGCGCGAGA
GCGACTACGCGATGGTTTCG

Downstream 100 bases:

>100_bases
CCGCGCGCTTTACGCACGCGATGCAAGCGGGGCTTCGGCCCTCATCGAACACACGAGATGGCTTTACTGCAAATTTCCGA
ACCCGGCATGGCGCCCGCGC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLRGVD
VGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVS
AEIGAQIERLEH

Sequences:

>Translated_172_residues
MKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLRGVD
VGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVS
AEIGAQIERLEH
>Mature_172_residues
MKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLRGVD
VGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVS
AEIGAQIERLEH

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=164, Percent_Identity=26.219512195122, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788876, Length=157, Percent_Identity=36.9426751592357, Blast_Score=110, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17541320, Length=144, Percent_Identity=26.3888888888889, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161084223, Length=168, Percent_Identity=31.547619047619, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19284; Mature: 19284

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAY
CCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHH
QTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAY
CCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHH
QTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA