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The map label for this gene is mdtA [H]

Identifier: 237812895

GI number: 237812895

Start: 2594945

End: 2596180

Strand: Direct

Name: mdtA [H]

Synonym: GBP346_A2654

Alternate gene names: 237812895

Gene position: 2594945-2596180 (Clockwise)

Preceding gene: 237812894

Following gene: 237812896

Centisome position: 63.31

GC content: 70.87

Gene sequence:

>1236_bases
ATGCCTTTCGTCACGCGCCGTAAGCTCGTCGCGTTCGCACTGCTGTCGCTCGGCGCGATCACGCTCGCCGCGTGGCTCGT
CAAACCCTCGGCCGACGCGCGCGCGGCGGGCGCGAAACAGGCCGACGCGGCGATCCCCGTCACGGCGGCCATCGTCGGCA
CGATGAACCTGCCCGTCTATCTAACCGGCGTCGGCGCCGTCACGCCGCAGTACGACGTGACCGTGAGAAGCCAGGTCGAC
GGCCAGATCACCCATGTGCGGTTCCACGAAGGCCAGCAGGTGCGCGCGGGCGACGTGCTCGTCGAGATCGATCGCCGCGC
GCTCCAGGCGACCGCCGACCAGGCGACAGCGAAGCTCGAGCAGGACAAGGCGACGCTCGCCAACGCCCGGCTCGAGCTCG
CGCGCCATCAGCGGCTCGCCGAAATGAACGCGGCGCCGGTGCAGATGCTGGATACATGGAAAGCGCGCGTCAACGAGCTG
CATGCGCAGATCCGCGGCGATCAGGCCGCCGTGCAGAACGCCCGCGTGGCCGTCGATTACACGACGATCCGCGCGCCCAT
CTCGGGGCGCATCGGCTTTCGGCTCGTCGACCAGGGCAACCTCGTGAAGGCCAACGATACGGCGCTGCTCACGCTCGTCA
CGACTTCGCCGATCACCGCGATCTATTCCGAATCGCAGGATGCACTGCCGGCGATCCAGGCGGCGCTGCGGCGCGGCGAG
GTCGAGGCCGTCGCGATGAGCACGGACGGCGAGACGACGCTCTCGCATGGGCGCCTGCGCACGATCGAGAACCGCGTCGA
TCCGACCAGCGGCGTGGTCCGGATGAAAGCGGTGTTCGAGAATGCCGACGGCGCGCTGTGGCCCGGGCAGTCGGTGATGA
TCCGCACCGTCGTCGACGTGCTGCGCAACGCGACGGCGGTGCCGGAGGACGCGATCCAGATCGGGCCGGACGGCAGCTTC
GTCTATGTGATCGGCGCCGGCGACAAGGTCGCGATGCGGCCCGTCGAGGTGTCGCATCGGGTGCTCGGCTACGCGGCCGT
CAAGCACGGCCTGCAAGCCGGCGAGCGCGTCGTCGTGCAGGGCCAGTACCGGTTGCAGGACGGCGCGCGCGTCGCCGCGA
CGATGATGCCGGCGCACGACGCACCCGACGCCGCCGCCGGCGCGCGGAACGCTCGCGCGCCGGCGGCGGGCCGCGAAGCG
CCCGCCGTGCCCGCGACGAACGCGCGCCGATCATGA

Upstream 100 bases:

>100_bases
GCCGTGACGCTTTCGCTCGAACCCGCGCCCTCCCGCTCACCGACACCGACATCGCGCCGCGATGCCGGCCGCATTCATTG
GTACGTCCACTCGCATGTCC

Downstream 100 bases:

>100_bases
GCCGGAACCTGTTCGCGGTGTTCATCCGCTACCCGGTCGCCACCTGCCTGATGACGGCGGGCATCCTGTTCGCGGGCGTG
GCCGCGTATTTTCATCTGCC

Product: efflux transporter, RND family, MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MPFVTRRKLVAFALLSLGAITLAAWLVKPSADARAAGAKQADAAIPVTAAIVGTMNLPVYLTGVGAVTPQYDVTVRSQVD
GQITHVRFHEGQQVRAGDVLVEIDRRALQATADQATAKLEQDKATLANARLELARHQRLAEMNAAPVQMLDTWKARVNEL
HAQIRGDQAAVQNARVAVDYTTIRAPISGRIGFRLVDQGNLVKANDTALLTLVTTSPITAIYSESQDALPAIQAALRRGE
VEAVAMSTDGETTLSHGRLRTIENRVDPTSGVVRMKAVFENADGALWPGQSVMIRTVVDVLRNATAVPEDAIQIGPDGSF
VYVIGAGDKVAMRPVEVSHRVLGYAAVKHGLQAGERVVVQGQYRLQDGARVAATMMPAHDAPDAAAGARNARAPAAGREA
PAVPATNARRS

Sequences:

>Translated_411_residues
MPFVTRRKLVAFALLSLGAITLAAWLVKPSADARAAGAKQADAAIPVTAAIVGTMNLPVYLTGVGAVTPQYDVTVRSQVD
GQITHVRFHEGQQVRAGDVLVEIDRRALQATADQATAKLEQDKATLANARLELARHQRLAEMNAAPVQMLDTWKARVNEL
HAQIRGDQAAVQNARVAVDYTTIRAPISGRIGFRLVDQGNLVKANDTALLTLVTTSPITAIYSESQDALPAIQAALRRGE
VEAVAMSTDGETTLSHGRLRTIENRVDPTSGVVRMKAVFENADGALWPGQSVMIRTVVDVLRNATAVPEDAIQIGPDGSF
VYVIGAGDKVAMRPVEVSHRVLGYAAVKHGLQAGERVVVQGQYRLQDGARVAATMMPAHDAPDAAAGARNARAPAAGREA
PAVPATNARRS
>Mature_410_residues
PFVTRRKLVAFALLSLGAITLAAWLVKPSADARAAGAKQADAAIPVTAAIVGTMNLPVYLTGVGAVTPQYDVTVRSQVDG
QITHVRFHEGQQVRAGDVLVEIDRRALQATADQATAKLEQDKATLANARLELARHQRLAEMNAAPVQMLDTWKARVNELH
AQIRGDQAAVQNARVAVDYTTIRAPISGRIGFRLVDQGNLVKANDTALLTLVTTSPITAIYSESQDALPAIQAALRRGEV
EAVAMSTDGETTLSHGRLRTIENRVDPTSGVVRMKAVFENADGALWPGQSVMIRTVVDVLRNATAVPEDAIQIGPDGSFV
YVIGAGDKVAMRPVEVSHRVLGYAAVKHGLQAGERVVVQGQYRLQDGARVAATMMPAHDAPDAAAGARNARAPAAGREAP
AVPATNARRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=346, Percent_Identity=38.4393063583815, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1786668, Length=324, Percent_Identity=33.0246913580247, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789929, Length=380, Percent_Identity=29.4736842105263, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789665, Length=373, Percent_Identity=28.9544235924933, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87081796, Length=375, Percent_Identity=24.2666666666667, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43634; Mature: 43503

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFVTRRKLVAFALLSLGAITLAAWLVKPSADARAAGAKQADAAIPVTAAIVGTMNLPVY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCCEE
LTGVGAVTPQYDVTVRSQVDGQITHVRFHEGQQVRAGDVLVEIDRRALQATADQATAKLE
EEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECCCEEEEEHHHHHHHHHHHHHHHHH
QDKATLANARLELARHQRLAEMNAAPVQMLDTWKARVNELHAQIRGDQAAVQNARVAVDY
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEE
TTIRAPISGRIGFRLVDQGNLVKANDTALLTLVTTSPITAIYSESQDALPAIQAALRRGE
EEEECCCCCCCCEEEECCCCEEEECCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCC
VEAVAMSTDGETTLSHGRLRTIENRVDPTSGVVRMKAVFENADGALWPGQSVMIRTVVDV
EEEEEEECCCCCHHCCCCEEEHHHCCCCCCCCEEEEEEHCCCCCCCCCCCHHHHHHHHHH
LRNATAVPEDAIQIGPDGSFVYVIGAGDKVAMRPVEVSHRVLGYAAVKHGLQAGERVVVQ
HHCCCCCCCCCEEECCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEE
GQYRLQDGARVAATMMPAHDAPDAAAGARNARAPAAGREAPAVPATNARRS
EEEEECCCCEEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PFVTRRKLVAFALLSLGAITLAAWLVKPSADARAAGAKQADAAIPVTAAIVGTMNLPVY
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCCEE
LTGVGAVTPQYDVTVRSQVDGQITHVRFHEGQQVRAGDVLVEIDRRALQATADQATAKLE
EEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECCCEEEEEHHHHHHHHHHHHHHHHH
QDKATLANARLELARHQRLAEMNAAPVQMLDTWKARVNELHAQIRGDQAAVQNARVAVDY
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEE
TTIRAPISGRIGFRLVDQGNLVKANDTALLTLVTTSPITAIYSESQDALPAIQAALRRGE
EEEECCCCCCCCEEEECCCCEEEECCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCC
VEAVAMSTDGETTLSHGRLRTIENRVDPTSGVVRMKAVFENADGALWPGQSVMIRTVVDV
EEEEEEECCCCCHHCCCCEEEHHHCCCCCCCCEEEEEEHCCCCCCCCCCCHHHHHHHHHH
LRNATAVPEDAIQIGPDGSFVYVIGAGDKVAMRPVEVSHRVLGYAAVKHGLQAGERVVVQ
HHCCCCCCCCCEEECCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEE
GQYRLQDGARVAATMMPAHDAPDAAAGARNARAPAAGREAPAVPATNARRS
EEEEECCCCEEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA