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The map label for this gene is serC [H]

Identifier: 237812875

GI number: 237812875

Start: 2568392

End: 2569486

Strand: Reverse

Name: serC [H]

Synonym: GBP346_A2634

Alternate gene names: 237812875

Gene position: 2569486-2568392 (Counterclockwise)

Preceding gene: 237812876

Following gene: 237812874

Centisome position: 62.69

GC content: 67.21

Gene sequence:

>1095_bases
ATGCATCGCAATCAACTGAATTTCTCCGGCGGCCCCGGCGCGCTGCCGGATACCGTGCTCGAACAGGTGCGGCAAGCGGT
GGTGGAGCTGCCGGAAACCGGCTTGTCGGTGCTCGGCATGAGCCATCGCTCGAGCTGGTTCTCGAGTCTGCTTGCGCAGG
CGCAGGCGGATCTGCGCGATCTGCTGGGCATTCCGGACGATTACGGCGTCGTGTTCCTGCAAGGCGGCAGCAGCCTGCAG
TTCTCGATGATCCCGATGAATTTCTCGCGGCCGGGCGCGGCCGCGCCCGAGTACGTGACGACGGGCTACTGGAGCCGCAA
GGCGATCGGCGAGGCGTCGCGCGTGGCCGCGATGCGCGTGGTCTGGGACGGCGCGGCGAGCGGCTACCGGACGCTGCCGT
CGCTCGCCGCGCTCGACTGGGACGCGCGCGCGCCGTTTCGTCACTACGTATCCAACGAGACCGTCGAAGGGCTGCAGTTT
CCCGACGCGGCGGATCTGCCCGGCAGCCCGCTGATCGCGGACATGTCGTCGGATTTCATGTCGAGGCCGTTCGACGTGCG
CGCGTACGGCATGGTCTACGCGCACGCGCAGAAGAATCTCGGGCCTGCCGGCGTGACGGTCGCGATCATCCGGCGCGCGC
TGCTCGAGCGCGTTCCGGACACGCTGCCGCCGATGCTCGATTTCCGCACGCACGTCGAGCATCGGTCGAACTACAACACG
CCGCCCGTGTTCGCGATCTACGTGATGGCGCTCGTGCTGCGCTGGATTTGGGACGAAATCGGCGGCGTGCATGCGATGCG
CGACATCAATGCGCGCAAGGCCGCCATGCTCTATGCGACGCTCGATGCGTTGAACGAAGTGATCGACTGCCATGCGCACA
GGGCGGCGCGCTCGACGATGAACGTCGCGTTCCGTTTCAGGCAGCCGCGGCTCGACACGCTGTTCAAGGAGCAGTCCACG
GAGGCGGGCTTCTGCGGCCTGAGCGGGCACCGCTCGATCGGCGGCATCCGCGCGTCGCTCTACAACGCCGTATCGGAGCA
GGCGGTGAGCCGGCTGTGCGCGTTCCTGAAGGACTTCGCGATCCGGCACGCGTGA

Upstream 100 bases:

>100_bases
CTGAACGCCGCGCTCAGGCGGGGCGCGACGCGTCCGTCCGCGGGCTATCTGCAGAAGTGATCCGATTCCGGTTCTCACCT
TGCCTCGGGAGTGTCGTCAG

Downstream 100 bases:

>100_bases
CGCGCGGCCGCGCGGCCGGCACCCGGCGCGCCGCCGCGCGCGTCGGCGCGGCACTTCGACGGCGTCGATTCAACCCGAAG
GAGATTGACCATGCTTTCCA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDDYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIWDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRHA

Sequences:

>Translated_364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDDYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIWDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRHA
>Mature_364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDDYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIWDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRHA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=367, Percent_Identity=40.0544959128065, Blast_Score=279, Evalue=3e-75,
Organism=Homo sapiens, GI10863955, Length=363, Percent_Identity=37.7410468319559, Blast_Score=241, Evalue=6e-64,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=38.6740331491713, Blast_Score=253, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=37.9120879120879, Blast_Score=271, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6324758, Length=387, Percent_Identity=34.8837209302326, Blast_Score=224, Evalue=1e-59,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=40.771349862259, Blast_Score=271, Evalue=4e-73,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40070; Mature: 40070

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LLGIPDDYGVVFLQGGSSLQFSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRV
HHCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHCCCCHHHHHCHHHHHHHHHH
VWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQFPDAADLPGSPLIADMSSDFM
EECCCCCCHHHCCHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHH
SRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
CCCCCEEHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PPVFAIYVMALVLRWIWDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTM
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVAFRFRQPRLDTLFKEQSTEAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFA
HHHHEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRHA
HCCC
>Mature Secondary Structure
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LLGIPDDYGVVFLQGGSSLQFSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRV
HHCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHCCCCHHHHHCHHHHHHHHHH
VWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQFPDAADLPGSPLIADMSSDFM
EECCCCCCHHHCCHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHH
SRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
CCCCCEEHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PPVFAIYVMALVLRWIWDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTM
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVAFRFRQPRLDTLFKEQSTEAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFA
HHHHEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRHA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA