Click here to switch to the map view.

The map label for this gene is map_1 [H]

Identifier: 237812810

GI number: 237812810

Start: 2495278

End: 2496093

Strand: Direct

Name: map_1 [H]

Synonym: GBP346_A2564

Alternate gene names: 237812810

Gene position: 2495278-2496093 (Clockwise)

Preceding gene: 237812809

Following gene: 237812811

Centisome position: 60.88

GC content: 65.2

Gene sequence:

>816_bases
ATGGCTATTACGCTCAAAAACGAACACGACATCGCGCAGATGCGCATCGCCTGCCGTCTCGCGAGCGAAGTGCTCGACTA
CATCACGCCATTCGTCGTCGCCGGCGTGACGACGGGCGAACTCGATCGCCTCTGCCACGAGTACATGACCCATGTGCAGG
GCACGGTGCCCGCGCCGCTCAATTACCAGCCGCCCGGCTATCCGCCGTTCCCGAAGGCGATCTGCACGTCGGTCAACGAC
GTGATCTGCCACGGCATCCCGGGCGAGAAGACGCTCAAGAACGGCGACGCGCTGAACATCGACATCACCGTCATCAAGAA
CGGCTATTTCGGCGACACGAGCCGGATGTTCATCATCGGCGAGGGCTCGATCCTCGCGAAGCGCCTCGTGCAAACCACCT
ACGAATGCATGTGGCTCGGCATCGACCAGGTGAGGCCCGGCGCGCATCTCGGCGACATCGGCCACGCGATCCAGAAGCAT
GCGGAAGCGCAAGGCTACAGCGTCGTGCGCGAATACTGCGGTCACGGCATCGGCACGGTGTTCCACGAGGACCCGCAAGT
CGTCCACTACGGGCGCCCGGGCACGGGCATCGAGCTCAAGCCGGGCATGATCTTCACGATCGAGCCGATGATCAACGCCG
GCAAGCGCGACATCCGCACGATGCCCGACCAGTGGACCGTCAAGACCCGCGACCGCAGCCTGTCCGCGCAGTGGGAGCAC
ACGATCCTCGTCACCGACACGGGTCACGAGGTGTTGACGGTGTCGGCCGGCACGCCGGCGCGCCCGACGTTCGCCGCGCC
GGCGACGGCGGCTTGA

Upstream 100 bases:

>100_bases
GAGCCGGCCGCGATTCGCGCGTCGCCGACCCGCGAAAGGCTGCGACGGCCGGAATAAGGTGCGATAATTGCGCAATTCAC
CGCATTTCAGGCATCGACTC

Downstream 100 bases:

>100_bases
GCGGCCCGCGCGCGCGCACCGGCATGCGCCGCCGCCCGCTTCGCCCGCCCCGGCCCGCTCGCGCGGCTCGCCCCGCCTGA
GCGGCGCGAGCCCGCACCAA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMTHVQGTVPAPLNYQPPGYPPFPKAICTSVND
VICHGIPGEKTLKNGDALNIDITVIKNGYFGDTSRMFIIGEGSILAKRLVQTTYECMWLGIDQVRPGAHLGDIGHAIQKH
AEAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TILVTDTGHEVLTVSAGTPARPTFAAPATAA

Sequences:

>Translated_271_residues
MAITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMTHVQGTVPAPLNYQPPGYPPFPKAICTSVND
VICHGIPGEKTLKNGDALNIDITVIKNGYFGDTSRMFIIGEGSILAKRLVQTTYECMWLGIDQVRPGAHLGDIGHAIQKH
AEAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TILVTDTGHEVLTVSAGTPARPTFAAPATAA
>Mature_270_residues
AITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMTHVQGTVPAPLNYQPPGYPPFPKAICTSVNDV
ICHGIPGEKTLKNGDALNIDITVIKNGYFGDTSRMFIIGEGSILAKRLVQTTYECMWLGIDQVRPGAHLGDIGHAIQKHA
EAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEHT
ILVTDTGHEVLTVSAGTPARPTFAAPATAA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=264, Percent_Identity=49.6212121212121, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI40385867, Length=253, Percent_Identity=40.3162055335968, Blast_Score=190, Evalue=1e-48,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=58.4313725490196, Blast_Score=314, Evalue=4e-87,
Organism=Escherichia coli, GI1788728, Length=254, Percent_Identity=25.5905511811024, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=263, Percent_Identity=44.8669201520913, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6323273, Length=253, Percent_Identity=45.0592885375494, Blast_Score=219, Evalue=2e-58,
Organism=Drosophila melanogaster, GI21355531, Length=262, Percent_Identity=46.1832061068702, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=38.5542168674699, Blast_Score=187, Evalue=5e-48,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29616; Mature: 29485

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMTHVQGTVPAPL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
NYQPPGYPPFPKAICTSVNDVICHGIPGEKTLKNGDALNIDITVIKNGYFGDTSRMFIIG
CCCCCCCCCCHHHHHCCHHHHEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLVQTTYECMWLGIDQVRPGAHLGDIGHAIQKHAEAQGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHHEEEHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEE
FHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
ECCCCCEEEECCCCCCEEECCCEEEEECCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCE
TILVTDTGHEVLTVSAGTPARPTFAAPATAA
EEEEEECCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMTHVQGTVPAPL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
NYQPPGYPPFPKAICTSVNDVICHGIPGEKTLKNGDALNIDITVIKNGYFGDTSRMFIIG
CCCCCCCCCCHHHHHCCHHHHEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLVQTTYECMWLGIDQVRPGAHLGDIGHAIQKHAEAQGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHHEEEHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEE
FHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
ECCCCCEEEECCCCCCEEECCCEEEEECCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCE
TILVTDTGHEVLTVSAGTPARPTFAAPATAA
EEEEEECCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]