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The map label for this gene is nahR [H]

Identifier: 237812737

GI number: 237812737

Start: 2430987

End: 2431916

Strand: Direct

Name: nahR [H]

Synonym: GBP346_A2490

Alternate gene names: 237812737

Gene position: 2430987-2431916 (Clockwise)

Preceding gene: 237812735

Following gene: 237812740

Centisome position: 59.31

GC content: 64.84

Gene sequence:

>930_bases
ATGAGCCAGCAACGCGAGGCGATCGACACGTATTTATTGCGCGTCCTGCATACTTTGCTGATGGAGCGCAGCGTGACGCG
CGCGGCCGTCAAGCTGAACCAGTCGCAACCGGCGATCAGCGCCGCGCTGCGCCGCCTGCGCGACATCACGGGCGACCCGC
TGCTCGTGCGCGGCAAGTCCGGCATGGTGCCGACCGAATACGGGTTGCGCCTGCTCGAACCCGTGCAGAACGCGCTGCGC
GAAATCGAGCGAATCAAGTTCCAGCAGCACAACTTCGATCCGGCGACGTCGATCCGCTGCTATCGGATCGGGTGCCCCGA
CTATCTGAACGTGCTGTTCGTGCCGACCGTCGTCGAACGCTTCCGTCAGGCCGCGCCGAACGCGACGCTCGAATTCCATT
CGCTCGGGCCCGCGTTCGACTACGAGCTCGCGCTCGAGGACGGCAAGCTCGACATCGTCGTCGGCAACTGGCCGGAGCCG
CCCGAGCAGTTGCATCTGTCGAACCTGTTCGTCGACGAGATCGTCTGCCTGATGAGCAACTCGCATCCGTTCGCCAAGCG
CGGCGGCCTCACGCTCGACCAGTATCTGAACGCGCCGCATCTCGCGCCGACGCCGTACTCGGTCGGGCAGCGCGGCGCGA
TCGACGTCCATCTCGCGCGCGAGCGCCTCAAGCGCCATGTCGTCGTCACGTTGCCGTACTTCAACCTCGCGCCGTACGTG
CTCGTGAAGTCTGATCTGATCTTCACGACGACACGGCTCTTCGCCGATCATTACGCGAAGTTCCTGCCGCTGTCGGTCGT
GCCCGCGCCGCTCGACTTTCCGCCGATGCAGTATTACCAGCTCTGGCACGAGCGCTGCCATTACTCGGACGAGGTGCGCT
GGTTGCGCGGGCTCGTCGCCGAGGCCACTCGCACGCTGATCGATGCTTGA

Upstream 100 bases:

>100_bases
CGACTCGAATGCGTCACGCTTGACGCTCCTTTATGTCCATATTAAAAACCATATACCCCCACCTGCAATCGATCAGCCCG
GACATATAAACGGAGAGAGC

Downstream 100 bases:

>100_bases
GGGTGGGATGCGCGGGATGCACGTGGCCTGGGCTTGATGTGCGTTGCGGCGGCGTTGACGGCGTCGGCAGCGGCGTCGGC
GTCGGCGTCGGCGTCGGCAG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALR
EIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFRQAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEP
PEQLHLSNLFVDEIVCLMSNSHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYV
LVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRGLVAEATRTLIDA

Sequences:

>Translated_309_residues
MSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALR
EIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFRQAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEP
PEQLHLSNLFVDEIVCLMSNSHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYV
LVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRGLVAEATRTLIDA
>Mature_308_residues
SQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALRE
IERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFRQAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPP
EQLHLSNLFVDEIVCLMSNSHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYVL
VKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRGLVAEATRTLIDA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=26.9102990033223, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790147, Length=298, Percent_Identity=23.8255033557047, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=27.9310344827586, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081904, Length=260, Percent_Identity=25, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35253; Mature: 35122

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCC
GMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
FRQAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPEQLHLSNLFVDEIVCLMSN
HHHHCCCCEEEECCCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
SHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYV
CCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCE
LVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRGLVA
EEECCHHHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
EATRTLIDA
HHHHHHHCC
>Mature Secondary Structure 
SQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCC
GMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
FRQAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPEQLHLSNLFVDEIVCLMSN
HHHHCCCCEEEECCCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
SHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYV
CCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCE
LVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRGLVA
EEECCHHHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
EATRTLIDA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]