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The map label for this gene is hflC [H]

Identifier: 237812540

GI number: 237812540

Start: 2257209

End: 2258108

Strand: Reverse

Name: hflC [H]

Synonym: GBP346_A2289

Alternate gene names: 237812540

Gene position: 2258108-2257209 (Counterclockwise)

Preceding gene: 237812541

Following gene: 237812539

Centisome position: 55.09

GC content: 69.67

Gene sequence:

>900_bases
ATGAACCGAATCATTGCGCTCGTCGTAGCGATCGTCATCGTCGCGCTGGTGGCCTCGTCGACGGTGCTCGTCGTCGATCC
GCGCCACACGGCCGTGCTGTCTTCGCGCGACGGCGGCACGCCGGCGCTTGCCGGCCCCGGTCTGCATTTCAAGCTGCCGC
AGCCGCTGCAAACCGCGACGCTCGTCGATGTCCGCGTGCAGACGCTCGACTCCGCCGATCCGTTGAGCCTCGCGACGAAG
GACAAGAGCGACGTGCTCGTGAGCCCCGTCGTCAAATACCGGATCGCCGACGCGCTCAAGTACTACAAGGAAACGGGCGG
CGCGCCGCGCGGCGAGGCGGACCGCCTGACGGCGGCGGCCAAGGGCGCGCTCGGCGCCGCGTTCGCGAAGCGCGATCTCG
ACGATGCGCTCGGCAGCCAGCGTGCGATCGCCGACGACGCGAAGCGCGCGTTGCAGGCCGACGCGGCGCCGCTTGGTATC
GACATCGTCGACGTGCAACTGACGCGCGTCGATCTGCCCGCCGCGCAAGCGGACGGCGCGTATCAGCGGATGACGGCCGA
ACTGCAGCGCGAGGCCGACCGCGAGCGCGCGGAGGGCGCGGCGCAAGCGGAGGAAATCAAGGCGGAGGCGGCCCGGCAGC
AGCAGACGATTCTCGCGGAAGGTTACAAGTCCGCGCAGTCGATCAAGGGCGAGGGCGACGCGAAGGCCGCGTCGATCGCC
GCCGACGCGTTCGGCCGCGATCCGCAGTTCTATCAGTTCTACGCGAGCCTGCAGGCGTATCGGAACAGCTTCAAGCCGAA
CGACGTGATCGTCGTCGATCCGGACAGCGAGTTCTTCCGCTTCATGCGCAGCCCGACGGGCGGCGCCGCGGCGCCGGCTG
CCGCGCCCCGCAACCGTTGA

Upstream 100 bases:

>100_bases
GCGGCGGCGAGCCCGGCGTCCGGCAGCGATTCGCGCTCGCGCGAGGCGTTGCGCAGCCGGTCGCGCACCGACGATCTGCA
GTAACGAGGAGCGCATCAAC

Downstream 100 bases:

>100_bases
TGTGCAAGGGGCGTCGTCGTCTGCATGGATCTCGCTGGCTCGTTACTGCTTGCTCTCGCGCTGATGCTCATCATCGAGGG
CGCCTTTCCGTTCGTGTTTC

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNRIIALVVAIVIVALVASSTVLVVDPRHTAVLSSRDGGTPALAGPGLHFKLPQPLQTATLVDVRVQTLDSADPLSLATK
DKSDVLVSPVVKYRIADALKYYKETGGAPRGEADRLTAAAKGALGAAFAKRDLDDALGSQRAIADDAKRALQADAAPLGI
DIVDVQLTRVDLPAAQADGAYQRMTAELQREADRERAEGAAQAEEIKAEAARQQQTILAEGYKSAQSIKGEGDAKAASIA
ADAFGRDPQFYQFYASLQAYRNSFKPNDVIVVDPDSEFFRFMRSPTGGAAAPAAAPRNR

Sequences:

>Translated_299_residues
MNRIIALVVAIVIVALVASSTVLVVDPRHTAVLSSRDGGTPALAGPGLHFKLPQPLQTATLVDVRVQTLDSADPLSLATK
DKSDVLVSPVVKYRIADALKYYKETGGAPRGEADRLTAAAKGALGAAFAKRDLDDALGSQRAIADDAKRALQADAAPLGI
DIVDVQLTRVDLPAAQADGAYQRMTAELQREADRERAEGAAQAEEIKAEAARQQQTILAEGYKSAQSIKGEGDAKAASIA
ADAFGRDPQFYQFYASLQAYRNSFKPNDVIVVDPDSEFFRFMRSPTGGAAAPAAAPRNR
>Mature_299_residues
MNRIIALVVAIVIVALVASSTVLVVDPRHTAVLSSRDGGTPALAGPGLHFKLPQPLQTATLVDVRVQTLDSADPLSLATK
DKSDVLVSPVVKYRIADALKYYKETGGAPRGEADRLTAAAKGALGAAFAKRDLDDALGSQRAIADDAKRALQADAAPLGI
DIVDVQLTRVDLPAAQADGAYQRMTAELQREADRERAEGAAQAEEIKAEAARQQQTILAEGYKSAQSIKGEGDAKAASIA
ADAFGRDPQFYQFYASLQAYRNSFKPNDVIVVDPDSEFFRFMRSPTGGAAAPAAAPRNR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=293, Percent_Identity=36.1774744027304, Blast_Score=164, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 31672; Mature: 31672

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIIALVVAIVIVALVASSTVLVVDPRHTAVLSSRDGGTPALAGPGLHFKLPQPLQTAT
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCCCCCCCCCCEEECCCCCCHHH
LVDVRVQTLDSADPLSLATKDKSDVLVSPVVKYRIADALKYYKETGGAPRGEADRLTAAA
HHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KGALGAAFAKRDLDDALGSQRAIADDAKRALQADAAPLGIDIVDVQLTRVDLPAAQADGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCCCH
YQRMTAELQREADRERAEGAAQAEEIKAEAARQQQTILAEGYKSAQSIKGEGDAKAASIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ADAFGRDPQFYQFYASLQAYRNSFKPNDVIVVDPDSEFFRFMRSPTGGAAAPAAAPRNR
HHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRIIALVVAIVIVALVASSTVLVVDPRHTAVLSSRDGGTPALAGPGLHFKLPQPLQTAT
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCCCCCCCCCCEEECCCCCCHHH
LVDVRVQTLDSADPLSLATKDKSDVLVSPVVKYRIADALKYYKETGGAPRGEADRLTAAA
HHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KGALGAAFAKRDLDDALGSQRAIADDAKRALQADAAPLGIDIVDVQLTRVDLPAAQADGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCCCH
YQRMTAELQREADRERAEGAAQAEEIKAEAARQQQTILAEGYKSAQSIKGEGDAKAASIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ADAFGRDPQFYQFYASLQAYRNSFKPNDVIVVDPDSEFFRFMRSPTGGAAAPAAAPRNR
HHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]