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The map label for this gene is kdgK [H]

Identifier: 237812477

GI number: 237812477

Start: 2187247

End: 2188236

Strand: Reverse

Name: kdgK [H]

Synonym: GBP346_A2226

Alternate gene names: 237812477

Gene position: 2188236-2187247 (Counterclockwise)

Preceding gene: 237812478

Following gene: 237812476

Centisome position: 53.39

GC content: 71.11

Gene sequence:

>990_bases
ATGCAAGTCCCGCTCGATGTCGTCACCTATGGCGAAGCGATGGCGATGTTCGTCGCCGCCGAACCCGGCCCGCTCGACAG
CGCGACGCATTTCACGAAGCGCATCGCGGGTGCCGATCTGAACGTCGCGATCGGCCTCGCGCGTCTCGGCTTCCGGGTCG
GCTGGATGAGCCGCGTCGGCGCCGATTCGTTCGGCCGCTACGTGCTCGACACGCTCGCGCGCGAGCAGGTCGACGCGTCG
TGCGTGACGGTCGACGCGCGCTACCCGACGGGCTTCCAGCTGAAGTCGCGCGCGACCGACGGCGCGGACCCGAGCGTCGA
GTATTTCCGCAAGGGCTCGGCCGCGAGCCGCCTGTCGCTCGACGACTACGTGCCCGATTACGTGCTCGGCGCGCGCCACC
TGCACCTGACGGGCGTCGCGCCCGCGCTGTCCGATTCGTCGCGCGAGCTCGCGTTCCATCTCGCGCGCACGACGCGCGCG
GCGGGCAAGACGGTGTCGTTCGATCCGAACCTGCGGCCCACGCTATGGCCGTCGCCGGAAGCGATGGCGCGCACGCTGAA
CGCGCTCGCCGAGCATGCGGACTGGGTGCTGCCGGGGCTCGCCGAAGGGCGCCAATTGACGGGCCTCGATACGCCCGCCG
ACATCGCGCGCTTCTATCTCGAGCGGGGCGCGCGCGGCGTGATCGTCAAGCTCGGCGCGGCGGGCGCGTACTTTCGCGTG
GCCGACGGCCGCGAGGGCGAGATCGCGGCCGAGCGCGTCGAGCACGTCGTCGATACGGTGGGCGCGGGCGACGGTTTCGC
GGTCGGCGTCGTGAGCGCGCTGCTCGAAGGCCGCGCGATCGACGAAGCGGTGGTGCGCGGCAACCGGATCGGCGCGCTCG
CGATCCAGGTGATCGGCGATTCGGAAGGACTGCCGACGCGCGCGGCGCTCGATCGAATCGAAAACCTGAGCAATGCGCGG
GATCGCCTAGAGGCGCCGCTCGCGCGATAA

Upstream 100 bases:

>100_bases
GGCTCGCGGCCGCATGAAACCCACCCACCGTCGCCCGGCTCGGCTAAGCTCGTTGTTTGCGCCGACGCCGGGCCGTTGAT
CGAAGGAGTCCGCCCACATC

Downstream 100 bases:

>100_bases
ACCGCCTGTCCCGACGCAGGACGGGCACAATCGCGGCGAATCCCGCGTTTCATACGGCGCCGCTCGACACAGGAGACACA
CATCATGTCCGCAACGCTCG

Product: 2-dehydro-3-deoxygluconokinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQVPLDVVTYGEAMAMFVAAEPGPLDSATHFTKRIAGADLNVAIGLARLGFRVGWMSRVGADSFGRYVLDTLAREQVDAS
CVTVDARYPTGFQLKSRATDGADPSVEYFRKGSAASRLSLDDYVPDYVLGARHLHLTGVAPALSDSSRELAFHLARTTRA
AGKTVSFDPNLRPTLWPSPEAMARTLNALAEHADWVLPGLAEGRQLTGLDTPADIARFYLERGARGVIVKLGAAGAYFRV
ADGREGEIAAERVEHVVDTVGAGDGFAVGVVSALLEGRAIDEAVVRGNRIGALAIQVIGDSEGLPTRAALDRIENLSNAR
DRLEAPLAR

Sequences:

>Translated_329_residues
MQVPLDVVTYGEAMAMFVAAEPGPLDSATHFTKRIAGADLNVAIGLARLGFRVGWMSRVGADSFGRYVLDTLAREQVDAS
CVTVDARYPTGFQLKSRATDGADPSVEYFRKGSAASRLSLDDYVPDYVLGARHLHLTGVAPALSDSSRELAFHLARTTRA
AGKTVSFDPNLRPTLWPSPEAMARTLNALAEHADWVLPGLAEGRQLTGLDTPADIARFYLERGARGVIVKLGAAGAYFRV
ADGREGEIAAERVEHVVDTVGAGDGFAVGVVSALLEGRAIDEAVVRGNRIGALAIQVIGDSEGLPTRAALDRIENLSNAR
DRLEAPLAR
>Mature_329_residues
MQVPLDVVTYGEAMAMFVAAEPGPLDSATHFTKRIAGADLNVAIGLARLGFRVGWMSRVGADSFGRYVLDTLAREQVDAS
CVTVDARYPTGFQLKSRATDGADPSVEYFRKGSAASRLSLDDYVPDYVLGARHLHLTGVAPALSDSSRELAFHLARTTRA
AGKTVSFDPNLRPTLWPSPEAMARTLNALAEHADWVLPGLAEGRQLTGLDTPADIARFYLERGARGVIVKLGAAGAYFRV
ADGREGEIAAERVEHVVDTVGAGDGFAVGVVSALLEGRAIDEAVVRGNRIGALAIQVIGDSEGLPTRAALDRIENLSNAR
DRLEAPLAR

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=318, Percent_Identity=27.9874213836478, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082281, Length=280, Percent_Identity=29.2857142857143, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790193, Length=306, Percent_Identity=26.1437908496732, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 35037; Mature: 35037

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVPLDVVTYGEAMAMFVAAEPGPLDSATHFTKRIAGADLNVAIGLARLGFRVGWMSRVG
CCCCCHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
ADSFGRYVLDTLAREQVDASCVTVDARYPTGFQLKSRATDGADPSVEYFRKGSAASRLSL
CHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCCCCCHHHHHCCCCCCCCCH
DDYVPDYVLGARHLHLTGVAPALSDSSRELAFHLARTTRAAGKTVSFDPNLRPTLWPSPE
HHCCCHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHH
AMARTLNALAEHADWVLPGLAEGRQLTGLDTPADIARFYLERGARGVIVKLGAAGAYFRV
HHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEE
ADGREGEIAAERVEHVVDTVGAGDGFAVGVVSALLEGRAIDEAVVRGNRIGALAIQVIGD
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEEEC
SEGLPTRAALDRIENLSNARDRLEAPLAR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQVPLDVVTYGEAMAMFVAAEPGPLDSATHFTKRIAGADLNVAIGLARLGFRVGWMSRVG
CCCCCHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
ADSFGRYVLDTLAREQVDASCVTVDARYPTGFQLKSRATDGADPSVEYFRKGSAASRLSL
CHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCCCCCHHHHHCCCCCCCCCH
DDYVPDYVLGARHLHLTGVAPALSDSSRELAFHLARTTRAAGKTVSFDPNLRPTLWPSPE
HHCCCHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHH
AMARTLNALAEHADWVLPGLAEGRQLTGLDTPADIARFYLERGARGVIVKLGAAGAYFRV
HHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEE
ADGREGEIAAERVEHVVDTVGAGDGFAVGVVSALLEGRAIDEAVVRGNRIGALAIQVIGD
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEEEC
SEGLPTRAALDRIENLSNARDRLEAPLAR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]