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The map label for this gene is lrp [C]

Identifier: 237812465

GI number: 237812465

Start: 2176681

End: 2177262

Strand: Reverse

Name: lrp [C]

Synonym: GBP346_A2214

Alternate gene names: 237812465

Gene position: 2177262-2176681 (Counterclockwise)

Preceding gene: 237812466

Following gene: 237812464

Centisome position: 53.12

GC content: 70.96

Gene sequence:

>582_bases
ATGGCCGCGCGAACGTTCGCCGGCGAGCGCGCCCGCGCGCAAACCCGCCCGCGCGGCGGCCGGCTTGGGCGCGCGGGCGT
TCGGCGCTATCATCGCGGCACCGCCATTCGCCGATCCGCCATGCGCCCACCCCGACTCGACCAACTCGACGACCTCGACC
GCAACCTCGTCGCGCTGCTGCAGGCGAACGCGCGCGCGAGCGTCGCGGATCTCGCGCGGCAGTTGGGCGTCGCGCGCACG
ACCGTGCTCGCGCGAATCGCGCGGCTCGAGCGTACGCAGGTGATCGCCGGCTACAGCGTGCGGCTCGGGCAGGACGTGCT
CGACGCGAGCATCTACGCGTACGTCGGCATCATCCTCGCGCCGAAGTACGGCAAGGACGTGCTCAAGCGCCTCGATCGCA
TGCCCGAGGTACAACTGCTGTGCGCGGTGAGCGGTGAGTACGATTACGTCGCGTGGCTGCGCGCCGACTCGCCCGAGCGC
CTGAACGACCTGCTCGATCAGATCGGCGCGCTCGAAGGCGTCGAGCGGACGACGACGTCGATCATCCTCGCGCGCAAGAT
CGATCGCGGGACGCTCGGCTGA

Upstream 100 bases:

>100_bases
CGTCGGTGGCCGCCGCGCGCGAGCGGGCGTCGCGCGCCGGCCGCCGAGCCCGGCCGCACGATGCGGCGATGCGCCTGCCG
TCACCGCGGCGGCGGCGCGC

Downstream 100 bases:

>100_bases
CGCGCGCCGCGCGCGACGACGGAGCGGATTTCGCTCACGACGGAGACCGGAAACATGACGACGAGCCCAACCTATTCGCG
GCCCGAGCGGCTGCTGCAGA

Product: transcriptional regulator, AsnC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MAARTFAGERARAQTRPRGGRLGRAGVRRYHRGTAIRRSAMRPPRLDQLDDLDRNLVALLQANARASVADLARQLGVART
TVLARIARLERTQVIAGYSVRLGQDVLDASIYAYVGIILAPKYGKDVLKRLDRMPEVQLLCAVSGEYDYVAWLRADSPER
LNDLLDQIGALEGVERTTTSIILARKIDRGTLG

Sequences:

>Translated_193_residues
MAARTFAGERARAQTRPRGGRLGRAGVRRYHRGTAIRRSAMRPPRLDQLDDLDRNLVALLQANARASVADLARQLGVART
TVLARIARLERTQVIAGYSVRLGQDVLDASIYAYVGIILAPKYGKDVLKRLDRMPEVQLLCAVSGEYDYVAWLRADSPER
LNDLLDQIGALEGVERTTTSIILARKIDRGTLG
>Mature_192_residues
AARTFAGERARAQTRPRGGRLGRAGVRRYHRGTAIRRSAMRPPRLDQLDDLDRNLVALLQANARASVADLARQLGVARTT
VLARIARLERTQVIAGYSVRLGQDVLDASIYAYVGIILAPKYGKDVLKRLDRMPEVQLLCAVSGEYDYVAWLRADSPERL
NDLLDQIGALEGVERTTTSIILARKIDRGTLG

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=149, Percent_Identity=32.8859060402685, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1790182, Length=145, Percent_Identity=28.9655172413793, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 21365; Mature: 21234

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARTFAGERARAQTRPRGGRLGRAGVRRYHRGTAIRRSAMRPPRLDQLDDLDRNLVALL
CCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
QANARASVADLARQLGVARTTVLARIARLERTQVIAGYSVRLGQDVLDASIYAYVGIILA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
PKYGKDVLKRLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGALEGVERTTTS
CCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHH
IILARKIDRGTLG
HHHHHHCCCCCCC
>Mature Secondary Structure 
AARTFAGERARAQTRPRGGRLGRAGVRRYHRGTAIRRSAMRPPRLDQLDDLDRNLVALL
CCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
QANARASVADLARQLGVARTTVLARIARLERTQVIAGYSVRLGQDVLDASIYAYVGIILA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
PKYGKDVLKRLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGALEGVERTTTS
CCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHH
IILARKIDRGTLG
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA