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The map label for this gene is corA [H]

Identifier: 237812456

GI number: 237812456

Start: 2170151

End: 2171128

Strand: Reverse

Name: corA [H]

Synonym: GBP346_A2205

Alternate gene names: 237812456

Gene position: 2171128-2170151 (Counterclockwise)

Preceding gene: 237812459

Following gene: 237812453

Centisome position: 52.97

GC content: 65.54

Gene sequence:

>978_bases
ATGCTGATCAACTGCGCCGCGTATCAGGATGGCCGCAAACTGGCCGATATCGACATCGACGACATCAGCGACTACGTCGC
GAAGCCCGAGTGCTTCGTCTGGGTCGCGCTGAAGGACCCGGAGCCGGACGAGATCGAGCGGATGGGCGAGGAGTTCGGCC
TGCACGAGCTCGCGCTCGAGGACGCGCGCAAGGGCCATCAGCGCCCGAAGATCGAGGAGTACGGCGATGCGCTGTTCGCC
GTGCTGCACACGGTCGAGATCGACGGGCAGGGCGAGCTTCAGGTGGGCGAGCTGAACGTGTTCGTCGGTCCGAACTATGT
GCTGTCGATCCGCAGTCACACCGAGCAGGACTTCCGCGCGGTGCGCGCGCGCTGCGAACGCGAGCCGCATCTGCTGAAGG
AGGGGGCCGCGTTCGTGTTCTACGCGCTGATGGACCAGGTCGTCGACCGCTATTTCCCGACGCTCGAGGCGCTCGGCGCC
GAGCTGGAAGCGCTCGAGGACCGGATCTTCGAGAAGACGGGCACGGCCGCCGCCCGCGCGCTGATCGAGGATCTGTACAG
GCTCAAGCGCCGGCTCGTGATGCTGCAGCAGCACACGGCGCCGCTCGTCGAGCCGCTCGCGAAACTCGTCGGCGGCCGCG
TTCCGCAGGTCTGCGCGGGGATGGACCATTACTTCCGCGATGTCTACGATCATCTGCTGCGGATCGTGCGAACGATCGAA
GGGCGGCGCGAGATGCTCGTCACCGCGATTCAGGTGAACCTCGGGATGATCTCGCTCGCGGAGAACGAAGTGACGAAGCG
GCTCGGTTCGTTCGCCGCGCTGTTCGCGATCCCGACGATGATCGCCGGGATCTACGGGATGAACTTCAACAACATACCGG
AGCTGCACTGGCGCTTCGGCTTCTACGTATGCCTCGGCGTGATGGCGGCCGCCGACCTGTTCCTCTGGCGGCGCTTCAGG
AAGGCCGGCTGGCTGTGA

Upstream 100 bases:

>100_bases
CATGACCAATATCGGCGGGCCGCGCAAGCGACGCGCGCCGGCCGGCGCGCGCGGGAGCGGCTAAACTGTGCGCCGGAATG
GCTTCGAAACCCGTAACAGC

Downstream 100 bases:

>100_bases
GCGGCGCTCACGCGGGCGCGGCGAGCTTGCCGATGACGACCATCCACGGCCGCACCCGCCAGCGCTTGACGAGGCCGTTC
GCGACGTAGGGATCGGCCTG

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLINCAAYQDGRKLADIDIDDISDYVAKPECFVWVALKDPEPDEIERMGEEFGLHELALEDARKGHQRPKIEEYGDALFA
VLHTVEIDGQGELQVGELNVFVGPNYVLSIRSHTEQDFRAVRARCEREPHLLKEGAAFVFYALMDQVVDRYFPTLEALGA
ELEALEDRIFEKTGTAAARALIEDLYRLKRRLVMLQQHTAPLVEPLAKLVGGRVPQVCAGMDHYFRDVYDHLLRIVRTIE
GRREMLVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFNNIPELHWRFGFYVCLGVMAAADLFLWRRFR
KAGWL

Sequences:

>Translated_325_residues
MLINCAAYQDGRKLADIDIDDISDYVAKPECFVWVALKDPEPDEIERMGEEFGLHELALEDARKGHQRPKIEEYGDALFA
VLHTVEIDGQGELQVGELNVFVGPNYVLSIRSHTEQDFRAVRARCEREPHLLKEGAAFVFYALMDQVVDRYFPTLEALGA
ELEALEDRIFEKTGTAAARALIEDLYRLKRRLVMLQQHTAPLVEPLAKLVGGRVPQVCAGMDHYFRDVYDHLLRIVRTIE
GRREMLVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFNNIPELHWRFGFYVCLGVMAAADLFLWRRFR
KAGWL
>Mature_325_residues
MLINCAAYQDGRKLADIDIDDISDYVAKPECFVWVALKDPEPDEIERMGEEFGLHELALEDARKGHQRPKIEEYGDALFA
VLHTVEIDGQGELQVGELNVFVGPNYVLSIRSHTEQDFRAVRARCEREPHLLKEGAAFVFYALMDQVVDRYFPTLEALGA
ELEALEDRIFEKTGTAAARALIEDLYRLKRRLVMLQQHTAPLVEPLAKLVGGRVPQVCAGMDHYFRDVYDHLLRIVRTIE
GRREMLVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFNNIPELHWRFGFYVCLGVMAAADLFLWRRFR
KAGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=305, Percent_Identity=23.9344262295082, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321058, Length=340, Percent_Identity=21.1764705882353, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324442, Length=139, Percent_Identity=28.0575539568345, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36989; Mature: 36989

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINCAAYQDGRKLADIDIDDISDYVAKPECFVWVALKDPEPDEIERMGEEFGLHELALE
CEEEECCCCCCCEEECCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCHHHHHHH
DARKGHQRPKIEEYGDALFAVLHTVEIDGQGELQVGELNVFVGPNYVLSIRSHTEQDFRA
HHHHCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECCCEEEEEHHCCHHHHHH
VRARCEREPHLLKEGAAFVFYALMDQVVDRYFPTLEALGAELEALEDRIFEKTGTAAARA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEDLYRLKRRLVMLQQHTAPLVEPLAKLVGGRVPQVCAGMDHYFRDVYDHLLRIVRTIE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GRREMLVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFNNIPELHWRFG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FYVCLGVMAAADLFLWRRFRKAGWL
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLINCAAYQDGRKLADIDIDDISDYVAKPECFVWVALKDPEPDEIERMGEEFGLHELALE
CEEEECCCCCCCEEECCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCHHHHHHH
DARKGHQRPKIEEYGDALFAVLHTVEIDGQGELQVGELNVFVGPNYVLSIRSHTEQDFRA
HHHHCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECCCEEEEEHHCCHHHHHH
VRARCEREPHLLKEGAAFVFYALMDQVVDRYFPTLEALGAELEALEDRIFEKTGTAAARA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEDLYRLKRRLVMLQQHTAPLVEPLAKLVGGRVPQVCAGMDHYFRDVYDHLLRIVRTIE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GRREMLVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFNNIPELHWRFG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FYVCLGVMAAADLFLWRRFRKAGWL
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]