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The map label for this gene is cheW [H]

Identifier: 237812281

GI number: 237812281

Start: 1978756

End: 1979268

Strand: Direct

Name: cheW [H]

Synonym: GBP346_A2029

Alternate gene names: 237812281

Gene position: 1978756-1979268 (Clockwise)

Preceding gene: 237812280

Following gene: 237812282

Centisome position: 48.28

GC content: 67.25

Gene sequence:

>513_bases
ATGAATGCAATTCTGGAAGCGCCGCACGCGGCGCGCATGAGCGGGCAGGACGCGGCGCGCGATGCGCAGGAATTCGTCAC
GTTCCGGCTCGGCACCGAGGAATACGGAATCGACATCCTGCGCGTGCAGGAGATCCGGTCGTATGAAGAGCCGACGCGCA
TCGCGAACGCGCCGGCGTTCATCAAGGGCGTGATCAACCTGCGCGGCGTGATCGTGCCGATCATCGACCTGCGCCTGAAG
TTCGCGCTCGATTCGGCCGAGTACAACACGTCGACGGTGGTCATCGTGCTGAACGTCGCGGCGCGCACGGTGGGCGTCGT
CGTCGACGCGGTGAGCGACGTGCTCGAACTCGCGGCCGCCGACCGGCCGCCGGCGCCCGAATTCGGCGCGGCGATCGACA
CCGGCTTCATCACGGACCTCGGATCGATCGCGGGCGAAAACGGCAACCGGATGCTGATCCTGCTCGACATCGAGCGGCTG
ATCGCGGCGGCGGACGTCGGGCTCGTCGGCTGA

Upstream 100 bases:

>100_bases
AACAAACCGGCGCCGGCTCTCGCCGCCGCCGCGACCGCAAGCGACGACTGGCAGACCTTCTGACGGCGGCGCGCAACCCC
AACGCGAGGAGGACAACGCA

Downstream 100 bases:

>100_bases
CCGGGCGTGGCCGATAGGCGCGGCATCGAGGGCGGGCCGGCAATGCCGGCGCCGCCCGCCGCGCTTTTTCGATCGATCGT
CCGGTGGGCACGCGGCGGCC

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MNAILEAPHAARMSGQDAARDAQEFVTFRLGTEEYGIDILRVQEIRSYEEPTRIANAPAFIKGVINLRGVIVPIIDLRLK
FALDSAEYNTSTVVIVLNVAARTVGVVVDAVSDVLELAAADRPPAPEFGAAIDTGFITDLGSIAGENGNRMLILLDIERL
IAAADVGLVG

Sequences:

>Translated_170_residues
MNAILEAPHAARMSGQDAARDAQEFVTFRLGTEEYGIDILRVQEIRSYEEPTRIANAPAFIKGVINLRGVIVPIIDLRLK
FALDSAEYNTSTVVIVLNVAARTVGVVVDAVSDVLELAAADRPPAPEFGAAIDTGFITDLGSIAGENGNRMLILLDIERL
IAAADVGLVG
>Mature_170_residues
MNAILEAPHAARMSGQDAARDAQEFVTFRLGTEEYGIDILRVQEIRSYEEPTRIANAPAFIKGVINLRGVIVPIIDLRLK
FALDSAEYNTSTVVIVLNVAARTVGVVVDAVSDVLELAAADRPPAPEFGAAIDTGFITDLGSIAGENGNRMLILLDIERL
IAAADVGLVG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=148, Percent_Identity=58.7837837837838, Blast_Score=174, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18115; Mature: 18115

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAILEAPHAARMSGQDAARDAQEFVTFRLGTEEYGIDILRVQEIRSYEEPTRIANAPAF
CCCCCCCCCHHHCCCCHHHHHHHHHHEEEECCHHHCEEEEEHHHHHCCCCCHHHCCCCHH
IKGVINLRGVIVPIIDLRLKFALDSAEYNTSTVVIVLNVAARTVGVVVDAVSDVLELAAA
HHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHC
DRPPAPEFGAAIDTGFITDLGSIAGENGNRMLILLDIERLIAAADVGLVG
CCCCCCCCCCHHCCHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCC
>Mature Secondary Structure
MNAILEAPHAARMSGQDAARDAQEFVTFRLGTEEYGIDILRVQEIRSYEEPTRIANAPAF
CCCCCCCCCHHHCCCCHHHHHHHHHHEEEECCHHHCEEEEEHHHHHCCCCCHHHCCCCHH
IKGVINLRGVIVPIIDLRLKFALDSAEYNTSTVVIVLNVAARTVGVVVDAVSDVLELAAA
HHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHC
DRPPAPEFGAAIDTGFITDLGSIAGENGNRMLILLDIERLIAAADVGLVG
CCCCCCCCCCHHCCHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]