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The map label for this gene is arcD [H]

Identifier: 237812265

GI number: 237812265

Start: 1963696

End: 1965156

Strand: Reverse

Name: arcD [H]

Synonym: GBP346_A2013

Alternate gene names: 237812265

Gene position: 1965156-1963696 (Counterclockwise)

Preceding gene: 237812267

Following gene: 237812264

Centisome position: 47.95

GC content: 66.94

Gene sequence:

>1461_bases
ATGGCTGAAGTCACACAAGAACAAGGCGTCGCGGCGAAATCCGCCGCGAACAAGCTGCGGCTCGGCGCGCTCACCGCGCT
CGTCGTCGGCTCGATGATCGGCGGCGGCATCTTCTCGCTGCCGCAGAACATGGCGGCCACCGCCGAAGCCGGCGCGATCC
TGATCGGCTGGGCGATCACCGCGATCGGCATGCTCACGCTCGCGTTCGTGTTCCAGACGCTCGCGAACCGCGAGCCGCAG
CTCGACGGCGGCGTGTACGCCTATGCGCAGGCGGGCTTCGGCGACTACATGGGCTTCTCGTCCGCGTGGGGCTACTGGAT
CAGCGCATGGCTCGGCAACGTCGGCTACTTCGTGCTGCTGTTCTCGACGCTCGGCTATTTCTTCCCCGTATTCGGCGAAG
GCAACACGCCCGCCGCGATCGCGGGCGCATCGGTGCTGCTGTGGGCCGTGCACTTTCTCGTGCTGCGCGGCATCCGGGAG
GCGGCGTTCGTCAATCTCGTCACCACCGTCGCGAAGATCGTCCCGCTCGTCGTCTTCATCCTGATCGGCTTCTTCGCGTT
CAAGCTCGACGTGTTCCGCACCGACATCTGGGGCCGCGCGAATCCGTCGCTCGGCTCGGTGATGAACCAGGTCCGCAACA
TGATGCTCGTCACCGTCTGGGTGTTCATCGGCATCGAAGGCGCGAGCATCTTCTCGGCGCGCGCGGAAAAGCGCAGCGAC
GTCGGCCGCGCGACCGTGATCGGCTTCGTCGGCGTGCTGCTCGCGCTCGTGCTGGTCAACGTGCTGTCGCTCGGCATCAT
GACGCAGCCGCAGCTCGCGAAGCTGCAGAACCCGTCGATGGCGGCCGTGCTCGAGCACGTGGTGGGCCACTGGGGCGCGG
TGCTCATCAGCGTCGGCCTCGTCGTCTCGCTCGCGGGCGCGCTGCTGTCCTGGGTGCTGCTCTGCGCGGAAATCATGTTC
TCGGCCGCGAAGGACCGCACGATGCCCGCGTTCCTGCGCAAGGAGAACGCGAACCATGTGCCGGCGAACGCGCTCTGGCT
CACGAACGCGATGGTCCAGGTGTTCCTGCTGATCACGCTCTTCTCGCAAAGCACCTATCTGTCGCTGATCTATCTGGCGA
CGTCGATGATCCTGATCCCGTACTTCTGGTCGGCCGCCTACGCGCTGCTCATCGCCGTGCGCGGCGAGACCTACGAGGGC
GACGCGCGCGCGCGCCGCAAGGACCTCTTCGTCGCCGCGCTCGCCGTGCTCTACGCGGTGTGGCTGCTGTACGCGGGCGG
CCTCAAGTATCTGCTGCTGTCCGCCCTTCTCTACGCGCCGGGCGCGCTCTTCTTCGCGAAGGCGAAGCGCGAGCTCGGCA
AGCCGGTCTTCACCGCCGCCGAAAAACTGATCTTCGCGGCAGCGGCCGCCGCCGCGCTCGCCGCGGCCTACGCGCTCCAC
AGCGGGCTCATCACACTTTGA

Upstream 100 bases:

>100_bases
AGGCGGCAAACCGCCGCGCTGCCTGGCCCCCGGGGCCGGGATGCGCGAGGCCCGCGTGCGCGCCGCGTTTTTGCACGTTC
CCGCTTGCGAGGAAAACATC

Downstream 100 bases:

>100_bases
TCGAAGAGGTAATCAACATGTCCCAAGCCATCCCTCAAGTCGGTGTCCATTCCGAAGTCGGCAAGCTGCGCAAGGTGCTC
GTCTGCTCGCCGGGCCTCGC

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MAEVTQEQGVAAKSAANKLRLGALTALVVGSMIGGGIFSLPQNMAATAEAGAILIGWAITAIGMLTLAFVFQTLANREPQ
LDGGVYAYAQAGFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPVFGEGNTPAAIAGASVLLWAVHFLVLRGIRE
AAFVNLVTTVAKIVPLVVFILIGFFAFKLDVFRTDIWGRANPSLGSVMNQVRNMMLVTVWVFIGIEGASIFSARAEKRSD
VGRATVIGFVGVLLALVLVNVLSLGIMTQPQLAKLQNPSMAAVLEHVVGHWGAVLISVGLVVSLAGALLSWVLLCAEIMF
SAAKDRTMPAFLRKENANHVPANALWLTNAMVQVFLLITLFSQSTYLSLIYLATSMILIPYFWSAAYALLIAVRGETYEG
DARARRKDLFVAALAVLYAVWLLYAGGLKYLLLSALLYAPGALFFAKAKRELGKPVFTAAEKLIFAAAAAAALAAAYALH
SGLITL

Sequences:

>Translated_486_residues
MAEVTQEQGVAAKSAANKLRLGALTALVVGSMIGGGIFSLPQNMAATAEAGAILIGWAITAIGMLTLAFVFQTLANREPQ
LDGGVYAYAQAGFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPVFGEGNTPAAIAGASVLLWAVHFLVLRGIRE
AAFVNLVTTVAKIVPLVVFILIGFFAFKLDVFRTDIWGRANPSLGSVMNQVRNMMLVTVWVFIGIEGASIFSARAEKRSD
VGRATVIGFVGVLLALVLVNVLSLGIMTQPQLAKLQNPSMAAVLEHVVGHWGAVLISVGLVVSLAGALLSWVLLCAEIMF
SAAKDRTMPAFLRKENANHVPANALWLTNAMVQVFLLITLFSQSTYLSLIYLATSMILIPYFWSAAYALLIAVRGETYEG
DARARRKDLFVAALAVLYAVWLLYAGGLKYLLLSALLYAPGALFFAKAKRELGKPVFTAAEKLIFAAAAAAALAAAYALH
SGLITL
>Mature_485_residues
AEVTQEQGVAAKSAANKLRLGALTALVVGSMIGGGIFSLPQNMAATAEAGAILIGWAITAIGMLTLAFVFQTLANREPQL
DGGVYAYAQAGFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPVFGEGNTPAAIAGASVLLWAVHFLVLRGIREA
AFVNLVTTVAKIVPLVVFILIGFFAFKLDVFRTDIWGRANPSLGSVMNQVRNMMLVTVWVFIGIEGASIFSARAEKRSDV
GRATVIGFVGVLLALVLVNVLSLGIMTQPQLAKLQNPSMAAVLEHVVGHWGAVLISVGLVVSLAGALLSWVLLCAEIMFS
AAKDRTMPAFLRKENANHVPANALWLTNAMVQVFLLITLFSQSTYLSLIYLATSMILIPYFWSAAYALLIAVRGETYEGD
ARARRKDLFVAALAVLYAVWLLYAGGLKYLLLSALLYAPGALFFAKAKRELGKPVFTAAEKLIFAAAAAAALAAAYALHS
GLITL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=440, Percent_Identity=47.5, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI2367353, Length=429, Percent_Identity=27.7389277389277, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786908, Length=433, Percent_Identity=26.3279445727483, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790575, Length=383, Percent_Identity=28.4595300261097, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51930; Mature: 51799

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
AEVTQEQGVAAKSAANKLRLGALTALVVGSMIGGGIFSLPQNMAATAEAGAILIGWAIT
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCHHHHHHHHH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CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]