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The map label for this gene is argF_2 [H]

Identifier: 237812263

GI number: 237812263

Start: 1961347

End: 1962357

Strand: Reverse

Name: argF_2 [H]

Synonym: GBP346_A2011

Alternate gene names: 237812263

Gene position: 1962357-1961347 (Counterclockwise)

Preceding gene: 237812264

Following gene: 237812262

Centisome position: 47.88

GC content: 65.08

Gene sequence:

>1011_bases
ATGAGCTTCAACCTGCACAACCGCAACCTGCTGAGCCTGATCCACCACAACGCGCGCGAGCTGCGCTATCTGCTCGACCT
CGCGCGGGATCTCAAGCGCGCGAAGTACAGCGGCACCGAGCAGCCGCGCCTGCTGCGCAAGAACATCGCGCTCATCTTCG
AGAAGACCTCGACCCGCACGCGCTGCGCGTTCGAAGTCGCCGCATACGATCAGGGCGCGAACGTCACGTACATCGATCCG
GCTTCGTCGCAGATCGGCCACAAGGAAAGCATGAGGGACACGGCGCGCGTGCTCGGGCGGATGTACGACGCGATCGAGTA
CCGTGGCTTCAGCCAGGAGATCGTCGAGGAGCTCGCGCACCACGCGGGCGTGCCCGTCTTCAACGGGCTCACCGACGAAT
ACCACCCGACGCAGATGCTCGCCGACGTGATGACGATGCGCGAGCACAGCGACAAGCCGCTGCACGACATCCGCTACGCC
TATCTCGGCGACGCGCGCAACAACATGGGCAATTCGCTGCTCCTGATCGGCGCGAAGCTCGGGATGGACGTGCGGATCGG
CGCGCCGAAGTCGCTCTGGCCCGCGGCCGACTTCATCGCGCAGTGCGAGGCGTTCGCGGCCGAGAGCGGCGCGCGGCTCA
CGCTGACCGAGGACCCGTACGAAGCGGTCAAGGGCGTCGACTTCATCCACACCGACGTGTGGGTGTCGATGGGCGAGCCC
GTCGAGGCCTGGGACGAGCGGATCAACGCGCTCCTGCCGTATCAGGTGAACCGCAAGCTGATCGAATCGACGGGCAATCC
GCGCACGCGCTTCATGCACTGCCTGCCGTCGTTCCACAACTGCGAGACGAAGGTCGGCAAGCAGATCGCCGAGCGCTATC
CGCACCTGAAGGACGGTATCGAAGTCACCGACGAAGTGTTCGAATCGCCGCGCTGCATCGCGTTCGAGCAGGCGGAAAAC
CGCATGCACACGATCAAGGCGGTCCTCGTGTCGACGCTCGGCGGCATCTGA

Upstream 100 bases:

>100_bases
ACCTGCCCGGTGCTGCGCGACCCCGTCGACTACTGAGCGCGAACCCAAGCGTCGCGGCGCGCGAGCGCCGCGCCCCCCGG
CAACCTAACGGAGAAACCAG

Downstream 100 bases:

>100_bases
AGGCGCGCCGCGCGCGATCGAGACGGGCGGCGCGCGAGGCTGCGCCGCCCGCACCGTCGGCACCGTTGACACAACAAGGA
GAAACATGATGCGTATCGTC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDP
ASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAHHAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYA
YLGDARNNMGNSLLLIGAKLGMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEP
VEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLKDGIEVTDEVFESPRCIAFEQAEN
RMHTIKAVLVSTLGGI

Sequences:

>Translated_336_residues
MSFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDP
ASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAHHAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYA
YLGDARNNMGNSLLLIGAKLGMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEP
VEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLKDGIEVTDEVFESPRCIAFEQAEN
RMHTIKAVLVSTLGGI
>Mature_335_residues
SFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDPA
SSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAHHAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYAY
LGDARNNMGNSLLLIGAKLGMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEPV
EAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLKDGIEVTDEVFESPRCIAFEQAENR
MHTIKAVLVSTLGGI

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=330, Percent_Identity=39.0909090909091, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI18105007, Length=333, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790703, Length=331, Percent_Identity=58.6102719033233, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1786469, Length=332, Percent_Identity=57.8313253012048, Blast_Score=403, Evalue=1e-114,
Organism=Escherichia coli, GI48994908, Length=381, Percent_Identity=24.6719160104987, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367364, Length=153, Percent_Identity=37.2549019607843, Blast_Score=68, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=330, Percent_Identity=31.2121212121212, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24642586, Length=341, Percent_Identity=24.3401759530792, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 38018; Mature: 37887

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCCC
RCAFEVAAYDQGANVTYIDPASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAH
CEEEEEEEECCCCCEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYAYLGDARNNMGNSLLLIGAKL
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCCCCCEEEEEEECC
GMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEP
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCC
VEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLKDGI
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCH
EVTDEVFESPRCIAFEQAENRMHTIKAVLVSTLGGI
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCCC
RCAFEVAAYDQGANVTYIDPASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAH
CEEEEEEEECCCCCEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYAYLGDARNNMGNSLLLIGAKL
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCCCCCEEEEEEECC
GMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEP
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCC
VEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLKDGI
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCH
EVTDEVFESPRCIAFEQAENRMHTIKAVLVSTLGGI
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA