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The map label for this gene is cobL [H]

Identifier: 237812246

GI number: 237812246

Start: 1946388

End: 1947614

Strand: Direct

Name: cobL [H]

Synonym: GBP346_A1994

Alternate gene names: 237812246

Gene position: 1946388-1947614 (Clockwise)

Preceding gene: 237812237

Following gene: 237812247

Centisome position: 47.49

GC content: 76.85

Gene sequence:

>1227_bases
ATGACCGCGTGGCTGACGGTGGTGGGCATCGGCGACGACGGATACGCGGGGCTCGGCAAGCCGGCGCGGCGCGCGCTCGC
CGACGCGGCGGTGGTGATGGGCGGCGAGCGGCATCTCGCGATGCTGCCCGCGCGGCATCGCGCGCAGCGCGCGCCTTGGC
CGAAGCCGTTCGATCTCGCGCCGCTCTTCGCGCGGCGTCCGGCGCGCGTGTGCGTGCTCGCGAGCGGCGATCCGATGCTG
TTCGGCGTCGGCGCGCTGCTCGCGCGCGCGCTCGCGCCGAACGAATGGCGCGTGCTGCCCGCGCCGTCGTCGCTGTCGCT
CGCGGCCGCGCGCACCGGCTGGCCGTTGCAGGACGTCGACGCGGTGTCGCTCGTCGGCCGGCCGCTCGCGTCGCTGCATC
GGCACCTGTATCCGGGCCAGCGGCTGTTCGTGCTGAGCGCGGACGGCGCGACGCCCGCCGCGATCGCCGGCGCGCTCGTC
GCGCGCGGCTTCGGGCCGAGCGCGATGAGCGTGTTCGAGCATCTCGGCGGCCCGCTCGAGCGGCGTCTCGACGCGCGCGC
CGATGCCTGGCGCGACGCGCGCGCGGCCGCGCTGAACGTCGTCGCGATCGAATGCCGCGCGTGCGCCGACGCGCCGCGCC
TGGCGCTCACCCCGGGCTTGCCGGACGACGCGTATCGCCACGACGGCCAGATCACGAAGCGCGATCTGCGCGCGCTCGCG
CTCGCGCGGCTCGCGCCCGCGCCGGGCGAATTGCTGTGGGACGTCGGCGCGGGCTGCGGGTCGATCGGTATCGAATGGAT
GCGCGCGCACCCGAGTTGCCGGACGATCGCGATCGAGGCGCATCCGGACCGGCAGCGCTTCATCGAGCACAACCGCGACG
CGCTCGGCGTGCCGGCGCTTGAGCTCGTCGCGGGCCGCGCGCCCGACGCGCTCGCGGGCCTGCGCGCGCCCGACGCGGTG
TTCGTCGGCGGCGGCGTGAGCCGCGAAGGCGTGCTCGACGCTTGCTGGGCGGGCCTGAAGCCGGGGGGGCGCTTCGTCGC
GCACGCGGTGACGCTGCAGGGCGAGGCGGCGCTCGTCGCGTGGCGCGAGCAGCATGGCGGCACGCTCACGCGGGTGTCGG
TCGCGCACGCGCAGCCGCTCGGCGGCTTCGACGCGTGGCGGCAGGCGCTGCCCGTCACGCTGTACGACGCGCGCAAGCCG
CGCGGCGCGCAGCCGGAGCACGCATGA

Upstream 100 bases:

>100_bases
ACGGACGCTGTATTATGCCTTTTTTCGCGACGCCCGAGCGCGGGATGCGCAGCGCGGGCGTCGCTTTCAGGATCGACGGA
AACACGATGGAGTACGACGG

Downstream 100 bases:

>100_bases
TGCGCGACGAAACCCCCGAGCAGCCGGCGCCGCTGCGCTTCGGCTACACGACGGGCAGCTGCGCGAGCGCGACGTCGCTC
GCCGCCGCGCGCCTGCTGCT

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating)

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTAWLTVVGIGDDGYAGLGKPARRALADAAVVMGGERHLAMLPARHRAQRAPWPKPFDLAPLFARRPARVCVLASGDPML
FGVGALLARALAPNEWRVLPAPSSLSLAAARTGWPLQDVDAVSLVGRPLASLHRHLYPGQRLFVLSADGATPAAIAGALV
ARGFGPSAMSVFEHLGGPLERRLDARADAWRDARAAALNVVAIECRACADAPRLALTPGLPDDAYRHDGQITKRDLRALA
LARLAPAPGELLWDVGAGCGSIGIEWMRAHPSCRTIAIEAHPDRQRFIEHNRDALGVPALELVAGRAPDALAGLRAPDAV
FVGGGVSREGVLDACWAGLKPGGRFVAHAVTLQGEAALVAWREQHGGTLTRVSVAHAQPLGGFDAWRQALPVTLYDARKP
RGAQPEHA

Sequences:

>Translated_408_residues
MTAWLTVVGIGDDGYAGLGKPARRALADAAVVMGGERHLAMLPARHRAQRAPWPKPFDLAPLFARRPARVCVLASGDPML
FGVGALLARALAPNEWRVLPAPSSLSLAAARTGWPLQDVDAVSLVGRPLASLHRHLYPGQRLFVLSADGATPAAIAGALV
ARGFGPSAMSVFEHLGGPLERRLDARADAWRDARAAALNVVAIECRACADAPRLALTPGLPDDAYRHDGQITKRDLRALA
LARLAPAPGELLWDVGAGCGSIGIEWMRAHPSCRTIAIEAHPDRQRFIEHNRDALGVPALELVAGRAPDALAGLRAPDAV
FVGGGVSREGVLDACWAGLKPGGRFVAHAVTLQGEAALVAWREQHGGTLTRVSVAHAQPLGGFDAWRQALPVTLYDARKP
RGAQPEHA
>Mature_407_residues
TAWLTVVGIGDDGYAGLGKPARRALADAAVVMGGERHLAMLPARHRAQRAPWPKPFDLAPLFARRPARVCVLASGDPMLF
GVGALLARALAPNEWRVLPAPSSLSLAAARTGWPLQDVDAVSLVGRPLASLHRHLYPGQRLFVLSADGATPAAIAGALVA
RGFGPSAMSVFEHLGGPLERRLDARADAWRDARAAALNVVAIECRACADAPRLALTPGLPDDAYRHDGQITKRDLRALAL
ARLAPAPGELLWDVGAGCGSIGIEWMRAHPSCRTIAIEAHPDRQRFIEHNRDALGVPALELVAGRAPDALAGLRAPDAVF
VGGGVSREGVLDACWAGLKPGGRFVAHAVTLQGEAALVAWREQHGGTLTRVSVAHAQPLGGFDAWRQALPVTLYDARKPR
GAQPEHA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43091; Mature: 42960

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAWLTVVGIGDDGYAGLGKPARRALADAAVVMGGERHLAMLPARHRAQRAPWPKPFDLA
CCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCCCC
PLFARRPARVCVLASGDPMLFGVGALLARALAPNEWRVLPAPSSLSLAAARTGWPLQDVD
CHHHCCCCEEEEEECCCCCEEHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCCCH
AVSLVGRPLASLHRHLYPGQRLFVLSADGATPAAIAGALVARGFGPSAMSVFEHLGGPLE
HHHHHCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
RRLDARADAWRDARAAALNVVAIECRACADAPRLALTPGLPDDAYRHDGQITKRDLRALA
HHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCEEECCCCCCHHHHCCCCCHHHHHHHHH
LARLAPAPGELLWDVGAGCGSIGIEWMRAHPSCRTIAIEAHPDRQRFIEHNRDALGVPAL
HHHHCCCCCHHHEECCCCCCHHCHHHEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCHH
ELVAGRAPDALAGLRAPDAVFVGGGVSREGVLDACWAGLKPGGRFVAHAVTLQGEAALVA
HHHHCCCCHHHHCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCEEEEE
WREQHGGTLTRVSVAHAQPLGGFDAWRQALPVTLYDARKPRGAQPEHA
EEHHCCCEEEEEEEECCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TAWLTVVGIGDDGYAGLGKPARRALADAAVVMGGERHLAMLPARHRAQRAPWPKPFDLA
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCCCC
PLFARRPARVCVLASGDPMLFGVGALLARALAPNEWRVLPAPSSLSLAAARTGWPLQDVD
CHHHCCCCEEEEEECCCCCEEHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCCCH
AVSLVGRPLASLHRHLYPGQRLFVLSADGATPAAIAGALVARGFGPSAMSVFEHLGGPLE
HHHHHCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
RRLDARADAWRDARAAALNVVAIECRACADAPRLALTPGLPDDAYRHDGQITKRDLRALA
HHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCEEECCCCCCHHHHCCCCCHHHHHHHHH
LARLAPAPGELLWDVGAGCGSIGIEWMRAHPSCRTIAIEAHPDRQRFIEHNRDALGVPAL
HHHHCCCCCHHHEECCCCCCHHCHHHEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCHH
ELVAGRAPDALAGLRAPDAVFVGGGVSREGVLDACWAGLKPGGRFVAHAVTLQGEAALVA
HHHHCCCCHHHHCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCEEEEE
WREQHGGTLTRVSVAHAQPLGGFDAWRQALPVTLYDARKPRGAQPEHA
EEHHCCCEEEEEEEECCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]