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The map label for this gene is hoxN [H]

Identifier: 237812229

GI number: 237812229

Start: 1928588

End: 1929883

Strand: Direct

Name: hoxN [H]

Synonym: GBP346_A1976

Alternate gene names: 237812229

Gene position: 1928588-1929883 (Clockwise)

Preceding gene: 237812228

Following gene: 237812230

Centisome position: 47.06

GC content: 66.98

Gene sequence:

>1296_bases
TTGCCCGCTTCACCCCCGTCCGACGCCGCGCGCTTCGGCGCACGTCGCGAACGCGCATGTCGCGAACGCGCACGTCGCAT
CCATCGCGAACGTGCACGTCGCGAACGACGCGCCGCCGCCGATGCCTGCCGGCGCAAGCGATCGACGGGCGCGGCGGGGG
AGCACGTGCATTGCACGCGATGCCGCGCGTGTTGGCATTCGTCTCGTTTGTCGACCGTTCGCAAAGGGAGCGCCATGCTC
GAATCGTTTCTTCGTCTCTTCAACGACAGCCCCGCCGAGCTGCGCAGCAAGATCGTCGGGATCTACGCGATGCTGATCGC
GTTCAACGTCGGCGCGTGGGCCTGGGCGTTCGCCGCGTTCCACGGCCAGCCGGTGCTGCTCGGCACCGCGCTCCTCGCGT
ATACGTTCGGGCTGCGCCATGCGGTCGACGCCGATCACATCGCCGCGATCGACAACGTCACGCGCAAGCTGATGCACGAG
AAGAAGAACCCGCTCGGCGCGGGGCTGTTCTTCTCGCTCGGGCATTCGAGCGTCGTGATCCTGATGACGGTGGCCGTCGC
GCTGACGGCCGCGACGCTCGCCGAGCGCTTCGAGGGCATGAAGGCATGGGGCGGCGCGATCGGCACGAGCGTGTCGGCGT
TCTTCCTGCTCGTGCTCGCGTTCGCGAACCTGCTGATCCTGATCTCCGTGTACCGGACGTTTCGCGCGGTGCGTCGCGGC
GAGCCGCTCGTCGAGCAGGATCTCGACATCCTGCTCAACCAGCGCGGCTTCTTCGCGCGGATCTTCCGGCCGCTGTTCGC
GATCGTGTCGCGCAGCTGGCACCTGTATCCGATCGGCTTCCTGTTCGGCCTCGGCTTCGACACCGCGACCGAGATCGCGC
TGTTCGGCATCTCGGCGACGCAGGCGCACGGCGGGCTGTCGTTCTGGTCGGTGATGGCGCTGCCCGTGCTGTTCACCGCG
GGCATGACGCTCGTCGACACCACCGACGGCATCATGATGATGGGCGCGTACCGCTGGGCATTCGTGCGGCCGATCCGCAA
GATCTACTACAACATGACGATCACGTTCGTATCGGTGCTCGTCGCGATCGTGATCGGCGGCATCGAGGCGCTCGCGCTGA
TCGGCGGCAAGCTCGCGCTCAAGGGCGGCGTGTGGGATTTCGCCGCGATGGCGGCCGAACACTTCGGCGTGCTCGGCTAC
TTCGTGATCGGCCTGTTCGCCGCGAGCTGGATCGTCTCCGCGCTCATCTACCGGATCAGGCGCTACGACGACATCGACGT
GACGCTCTCCGCGTGA

Upstream 100 bases:

>100_bases
CTCGCGCGCATGCGCCGCCGCGGTAGCGGGCGGCCCCAGGGTTCAGCGCCGCGGGGATGCGGCGTGTCGTCCACGGCTGC
ATCGCGCCGCTTGCCGCGGC

Downstream 100 bases:

>100_bases
GGCCCGCGCGGGGCGCTTCCCCATGAGCTCATGCGCCGCGCGCGTCGCACGCCGCCGCGGCACCGGCCCGAGGCCCGATT
ACCCCTTACTCCATGACCCG

Product: high-affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MPASPPSDAARFGARRERACRERARRIHRERARRERRAAADACRRKRSTGAAGEHVHCTRCRACWHSSRLSTVRKGSAML
ESFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAFHGQPVLLGTALLAYTFGLRHAVDADHIAAIDNVTRKLMHE
KKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVRRG
EPLVEQDLDILLNQRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLFTA
GMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAIVIGGIEALALIGGKLALKGGVWDFAAMAAEHFGVLGY
FVIGLFAASWIVSALIYRIRRYDDIDVTLSA

Sequences:

>Translated_431_residues
MPASPPSDAARFGARRERACRERARRIHRERARRERRAAADACRRKRSTGAAGEHVHCTRCRACWHSSRLSTVRKGSAML
ESFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAFHGQPVLLGTALLAYTFGLRHAVDADHIAAIDNVTRKLMHE
KKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVRRG
EPLVEQDLDILLNQRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLFTA
GMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAIVIGGIEALALIGGKLALKGGVWDFAAMAAEHFGVLGY
FVIGLFAASWIVSALIYRIRRYDDIDVTLSA
>Mature_430_residues
PASPPSDAARFGARRERACRERARRIHRERARRERRAAADACRRKRSTGAAGEHVHCTRCRACWHSSRLSTVRKGSAMLE
SFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAFHGQPVLLGTALLAYTFGLRHAVDADHIAAIDNVTRKLMHEK
KNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVRRGE
PLVEQDLDILLNQRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLFTAG
MTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAIVIGGIEALALIGGKLALKGGVWDFAAMAAEHFGVLGYF
VIGLFAASWIVSALIYRIRRYDDIDVTLSA

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 47473; Mature: 47342

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASPPSDAARFGARRERACRERARRIHRERARRERRAAADACRRKRSTGAAGEHVHCTR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
CRACWHSSRLSTVRKGSAMLESFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HGQPVLLGTALLAYTFGLRHAVDADHIAAIDNVTRKLMHEKKNPLGAGLFFSLGHSSVVI
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHH
LMTVAVALTAATLAERFEGMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPLVEQDLDILLNQRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISAT
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHCCCCHH
QAHGGLSFWSVMALPVLFTAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVL
HCCCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAIVIGGIEALALIGGKLALKGGVWDFAAMAAEHFGVLGYFVIGLFAASWIVSALIYRIR
HHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYDDIDVTLSA
CCCCCCEEECC
>Mature Secondary Structure 
PASPPSDAARFGARRERACRERARRIHRERARRERRAAADACRRKRSTGAAGEHVHCTR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH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CCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]