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The map label for this gene is infC [H]

Identifier: 237812017

GI number: 237812017

Start: 1706018

End: 1706488

Strand: Direct

Name: infC [H]

Synonym: GBP346_A1758

Alternate gene names: 237812017

Gene position: 1706018-1706488 (Clockwise)

Preceding gene: 237812016

Following gene: 237812018

Centisome position: 41.62

GC content: 58.17

Gene sequence:

>471_bases
GTGCGTCTGGTCGGGGTCGATGGTGAGCCCATCGGCATCGTGAAACTCGCCGAGGCTTTCCGTAAATCGGAAGAGCTGGA
TGTTGACCTGGTGGAGATTGCGCCGCAGGCGGCTCCGCCGGTTTGCCGTCTGATGGATTACGGCAAGTTCAAGTACCAGG
AAGCCAAGAAGCAGCACGAGGCGAAGCTCAAGCAAAAGGTCATCCAGGTCAAGGAAGTGAAATTCCGCCCGGGAACCGAT
GACGGCGATTACAACGTCAAGCTTCGCAATCTGGTGCGCTTCCTCGAGGAAGGCGACAAGACGAAGATCACGTTGCGTTT
CCGCGGCCGTGAAATGGCTCACCAGGAAATCGGCATGCGCATGCTCGAGCGCCTGCGCGGCGATCTCGACGAGGTCGGCC
AGGTCGAGCAGATGCCGAAGATGGAAGGGCGCCAGATGATCATGGTGCTCTCGCCGAAGAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
CCCTGGCAGCGCGGCTCGTTTTTTTAATTTTTAGAGGAAACGTAACATCGCTACTGATAAGTCGTCGCATCGCATCAACG
GTGAAATCACTGCGCCGGAA

Downstream 100 bases:

>100_bases
CGAAGCGCCGCGCGAGCGCGGTGCTTCGATGAAGGGGTTCGGCGCGTCGTCCGGTCAGGGCGGCGCGCCAGAAACGGCGG
CGGTCGCGTGAGCGTACGCG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRLVGVDGEPIGIVKLAEAFRKSEELDVDLVEIAPQAAPPVCRLMDYGKFKYQEAKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRGDLDEVGQVEQMPKMEGRQMIMVLSPKKKK

Sequences:

>Translated_156_residues
MRLVGVDGEPIGIVKLAEAFRKSEELDVDLVEIAPQAAPPVCRLMDYGKFKYQEAKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRGDLDEVGQVEQMPKMEGRQMIMVLSPKKKK
>Mature_156_residues
MRLVGVDGEPIGIVKLAEAFRKSEELDVDLVEIAPQAAPPVCRLMDYGKFKYQEAKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRGDLDEVGQVEQMPKMEGRQMIMVLSPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=157, Percent_Identity=68.7898089171974, Blast_Score=206, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18041; Mature: 18041

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVGVDGEPIGIVKLAEAFRKSEELDVDLVEIAPQAAPPVCRLMDYGKFKYQEAKKQHE
CEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHH
AKLKQKVIQVKEVKFRPGTDDGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMR
HHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHH
MLERLRGDLDEVGQVEQMPKMEGRQMIMVLSPKKKK
HHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRLVGVDGEPIGIVKLAEAFRKSEELDVDLVEIAPQAAPPVCRLMDYGKFKYQEAKKQHE
CEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHH
AKLKQKVIQVKEVKFRPGTDDGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMR
HHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHH
MLERLRGDLDEVGQVEQMPKMEGRQMIMVLSPKKKK
HHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]