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The map label for this gene is yafC [H]

Identifier: 237812011

GI number: 237812011

Start: 1697634

End: 1698635

Strand: Direct

Name: yafC [H]

Synonym: GBP346_A1751

Alternate gene names: 237812011

Gene position: 1697634-1698635 (Clockwise)

Preceding gene: 237812007

Following gene: 237812012

Centisome position: 41.42

GC content: 70.46

Gene sequence:

>1002_bases
ATGTTAGTTTTCCGATTTCGATATAAATACGGGCCAAGAGCGAATGAATTCTTCGCAAAAAGGAAAGATTGCGCGGGGCC
GTCGGCGAGGCGGCCGATGCTGATCGACGATCTGCCGGCGCTCGCGACATTCGCGCGGATCGTCGCGGCGGGCAGTCTGT
CAGCCGCGGCGCGTGAGCTCGATCTGTCGCTGTCGGTGGTCAGCAAGCGGCTCGCGCAGCTCGAAACGCGGCTGGGCGTG
CGGCTGTTGCAGCGGACGACGCGTCAGCAGACACTGACCGACGAGGGCGCGCTGTTCCACGCGCAAGTCGTGAGGATCCT
CGCGGAGATCGAGCAGGCCGAATCGCTGATGCGCGAGCGCCGCGGCACCGTGAGCGGCGCGCTGCGGATCACGGCGCCCG
GCGAGCTCGGGCGGCGGCGGATCGCGCCCATCGTCGCCGCGTTCCAGCGGCAGCATCCGCAGGTGACGGTGCAGATGCAG
CTCACCGATGCCGTCGTCGACCTCATCGCGCACGACGTCGACGTCGCGGTGCGGATCGGCATGCTCGCGGATTCGTCGCT
GATCGCGCGCGAGCTCGCGCCGAACTACCGCGTGCTGTGTGCGTCGCCCGCGTATCTCGCCGAGCACGGCATGCCCGCGC
AGCCCGCCGATCTGTGCGCGCACCGGTGCATCGTGCTGGGCGAGCAGCCGCGCGTCGAATGGCGCTTCGACGGGCCGCGG
CCCGCGGCGGTCGAGGTGTCGGCCGCGTTCCTGACGAACGACGGCGGCGCGGCCCGCACGCTCGCGCTGGAAGGCGCGGG
CATCGCGCTGAAATCGATTTGGGACGTGGGGCCGGACCTCGCCGCGGGGCGGCTGCGGCGCGTGCTGCCCGAATGCGCGT
CGAGCGCCGCGCCGTTGCACGCGGTCTATCCGAGCGGCCGGCATCTCGCGCTGCGCGTGCGGACGTTCGTCGACTATCTC
GGCGTCGAGCTGCGCCGCGCGTGGCGCTGGGACGAGCGATGA

Upstream 100 bases:

>100_bases
GGCGGGCATCGGAATCTCCTTGTGTGCGTTGCGTGGCGCGCGATGCCTGACGGCGATCGCGCGGAATGTCGTCCGCCTCG
TTCGTACGGCGGCGGCATTC

Downstream 100 bases:

>100_bases
CGTGCGGCGGCCGGCGCGCGGCCGCATGGCGGCGGGGCCCGGCGATCAGGCGGCCGGCGATCGGACGGCCGCGTTTCGCA
TGCGCGGCCGCTTCTCCGTG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MLVFRFRYKYGPRANEFFAKRKDCAGPSARRPMLIDDLPALATFARIVAAGSLSAAARELDLSLSVVSKRLAQLETRLGV
RLLQRTTRQQTLTDEGALFHAQVVRILAEIEQAESLMRERRGTVSGALRITAPGELGRRRIAPIVAAFQRQHPQVTVQMQ
LTDAVVDLIAHDVDVAVRIGMLADSSLIARELAPNYRVLCASPAYLAEHGMPAQPADLCAHRCIVLGEQPRVEWRFDGPR
PAAVEVSAAFLTNDGGAARTLALEGAGIALKSIWDVGPDLAAGRLRRVLPECASSAAPLHAVYPSGRHLALRVRTFVDYL
GVELRRAWRWDER

Sequences:

>Translated_333_residues
MLVFRFRYKYGPRANEFFAKRKDCAGPSARRPMLIDDLPALATFARIVAAGSLSAAARELDLSLSVVSKRLAQLETRLGV
RLLQRTTRQQTLTDEGALFHAQVVRILAEIEQAESLMRERRGTVSGALRITAPGELGRRRIAPIVAAFQRQHPQVTVQMQ
LTDAVVDLIAHDVDVAVRIGMLADSSLIARELAPNYRVLCASPAYLAEHGMPAQPADLCAHRCIVLGEQPRVEWRFDGPR
PAAVEVSAAFLTNDGGAARTLALEGAGIALKSIWDVGPDLAAGRLRRVLPECASSAAPLHAVYPSGRHLALRVRTFVDYL
GVELRRAWRWDER
>Mature_333_residues
MLVFRFRYKYGPRANEFFAKRKDCAGPSARRPMLIDDLPALATFARIVAAGSLSAAARELDLSLSVVSKRLAQLETRLGV
RLLQRTTRQQTLTDEGALFHAQVVRILAEIEQAESLMRERRGTVSGALRITAPGELGRRRIAPIVAAFQRQHPQVTVQMQ
LTDAVVDLIAHDVDVAVRIGMLADSSLIARELAPNYRVLCASPAYLAEHGMPAQPADLCAHRCIVLGEQPRVEWRFDGPR
PAAVEVSAAFLTNDGGAARTLALEGAGIALKSIWDVGPDLAAGRLRRVLPECASSAAPLHAVYPSGRHLALRVRTFVDYL
GVELRRAWRWDER

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=37.5, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=37.6712328767123, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1789440, Length=283, Percent_Identity=33.5689045936396, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=31.25, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=29.0657439446367, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=31.6498316498317, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=26.3698630136986, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=26, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787601, Length=138, Percent_Identity=29.7101449275362, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=24.7386759581882, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786448, Length=293, Percent_Identity=27.3037542662116, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788706, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=141, Percent_Identity=31.9148936170213, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36607; Mature: 36607

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVFRFRYKYGPRANEFFAKRKDCAGPSARRPMLIDDLPALATFARIVAAGSLSAAAREL
CEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHCHHHHHHHHHHHHHCCHHHHHHHH
DLSLSVVSKRLAQLETRLGVRLLQRTTRQQTLTDEGALFHAQVVRILAEIEQAESLMRER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGTVSGALRITAPGELGRRRIAPIVAAFQRQHPQVTVQMQLTDAVVDLIAHDVDVAVRIG
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCHHHHEEEE
MLADSSLIARELAPNYRVLCASPAYLAEHGMPAQPADLCAHRCIVLGEQPRVEWRFDGPR
HHCCHHHHHHHHCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHEEECCCCCEEEEECCCC
PAAVEVSAAFLTNDGGAARTLALEGAGIALKSIWDVGPDLAAGRLRRVLPECASSAAPLH
CCEEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEE
AVYPSGRHLALRVRTFVDYLGVELRRAWRWDER
EECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLVFRFRYKYGPRANEFFAKRKDCAGPSARRPMLIDDLPALATFARIVAAGSLSAAAREL
CEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHCHHHHHHHHHHHHHCCHHHHHHHH
DLSLSVVSKRLAQLETRLGVRLLQRTTRQQTLTDEGALFHAQVVRILAEIEQAESLMRER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGTVSGALRITAPGELGRRRIAPIVAAFQRQHPQVTVQMQLTDAVVDLIAHDVDVAVRIG
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCHHHHEEEE
MLADSSLIARELAPNYRVLCASPAYLAEHGMPAQPADLCAHRCIVLGEQPRVEWRFDGPR
HHCCHHHHHHHHCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHEEECCCCCEEEEECCCC
PAAVEVSAAFLTNDGGAARTLALEGAGIALKSIWDVGPDLAAGRLRRVLPECASSAAPLH
CCEEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEE
AVYPSGRHLALRVRTFVDYLGVELRRAWRWDER
EECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]