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The map label for this gene is mdtA [H]

Identifier: 237811650

GI number: 237811650

Start: 1337819

End: 1339138

Strand: Reverse

Name: mdtA [H]

Synonym: GBP346_A1387

Alternate gene names: 237811650

Gene position: 1339138-1337819 (Counterclockwise)

Preceding gene: 237811652

Following gene: 237811649

Centisome position: 32.67

GC content: 70.23

Gene sequence:

>1320_bases
ATGGACAATCAAGAAAAGCCCACGCCCCGCTCTCCCGCTCCCGCGCCCTCCGGTCCCCGCCCGCGCCGCAGGCTGATCGC
ATTCGGCGTGCTCGCGGCCGTCGCGATCGGCGCCCTGCTGTGGTGGCATCCGTGGAAGAGCGGCGGCCCCCCGAGCGCCC
AGGGCCAGCCGGGCGGCGCGCGCCAGCGGGGCGGCCCCGCCGCGCTCGCGAACCTGCCGCAGCCGGTGCAGGTCGCCACG
GCGGCGCGCGGCGAGATGCCCGTCGTCCTCAACGCGCTCGGCACCGTCACGCCGCTCGCGAACGTGACCGTCCGGACCCA
GCTGTCCGGCTATCTGCAGGCGGTGTCGTTCCAGGAAGGCCAGATCGTGAAGAAGGGCGACGTGCTCGCGCAAATCGATC
CGCGCCCGTACCAGATCTCGCTCGCGAACGCGCAAGGCGCGCTCGCGCGCGACGAGGCGCTCCTCGCGACCGCGCGCCTC
GACCTGAAGCGCTATCAGACGCTCGTCGCGCAAGACTCGATCGCGAAGCAGACGGCCGACACGCAGGCCTCGCTCGTCAA
GCAGTACGAAGGCACCGTGCAGATCGACCGCGCGGCGATCGACTCCGCGAAGCTCAATCTCGCGTACGCGCGCATCACCG
CGCCCGTATCGGGCCGCGTCGGCCTGCGGCAGGTGGACCCGGGCAATTACGTGACGCCGTCGGACACGAACGGCATCGTC
GTCATCACGCAACTGCAGCCGATGAGCGTGATCTTCACCACGTCGGAGGACAATCTGCCCGCGATCCTCAAGCAGGTGGG
CGCGGGCGGCAAGCTGTCGGTCACCGCGTACAACCGCAACAACACGACGCCGCTCGAGACGGGCGTGCTCGACACGCTCG
ACAACCAGATCGACACGGCCACCGGCACCGTGAAGCTGCGCGCGCGCTTCGAGAACCGGAACAACCTGCTGTTCCCGAAT
CAGTTCGTCAACACGCGGCTGCTCGTCGACACGATCCGCGATGCGACGATCGTGCCGACGTCGGCCGTGCTCACGGGCTC
GATCGGCCAGTTCGTCTACGTCGTGAAGCCGGACAACACGGTGAGCGTGCGCAATGTGAAGCCCGGCCCCGTCGACGGCG
AGCGCACGAGCATCGTCGAGGGGCTCGCCGTCGGCGAGCGCGTCGTGACGGACGGCTCCGACCGGTTGCGCGAAGGCTCG
GCGGTGACGATCCCGGCCGACAAGCCGAAGCAGGCTTCGGGCGCAAGAAGCGCTTCGGGCGCTTCGGGCGCGCACGGCGG
GCACCGTCGCCGCGGCGCGTCGCAAGCCCGATCGCAATGA

Upstream 100 bases:

>100_bases
CGTCGCGACCGGGCTGCGGCCGGCCCGCGTCGCGCCGACCGCGAACGCGGCCCGTGCGCGCCCGTCGTATGCGCCGCACG
CCGACCTCCAGATCGAACCG

Downstream 100 bases:

>100_bases
CGCCGGCTGACCGATGAATCCGTCCCGCGTCTTCATTCTCCGGCCGGTCGGCACCGCGCTCCTGATGGCGGCGATCATGC
TCGCCGGCCTCGTCGCGCTG

Product: membrane fusion protein MdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MDNQEKPTPRSPAPAPSGPRPRRRLIAFGVLAAVAIGALLWWHPWKSGGPPSAQGQPGGARQRGGPAALANLPQPVQVAT
AARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSFQEGQIVKKGDVLAQIDPRPYQISLANAQGALARDEALLATARL
DLKRYQTLVAQDSIAKQTADTQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTNGIV
VITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQIDTATGTVKLRARFENRNNLLFPN
QFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKPDNTVSVRNVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGS
AVTIPADKPKQASGARSASGASGAHGGHRRRGASQARSQ

Sequences:

>Translated_439_residues
MDNQEKPTPRSPAPAPSGPRPRRRLIAFGVLAAVAIGALLWWHPWKSGGPPSAQGQPGGARQRGGPAALANLPQPVQVAT
AARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSFQEGQIVKKGDVLAQIDPRPYQISLANAQGALARDEALLATARL
DLKRYQTLVAQDSIAKQTADTQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTNGIV
VITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQIDTATGTVKLRARFENRNNLLFPN
QFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKPDNTVSVRNVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGS
AVTIPADKPKQASGARSASGASGAHGGHRRRGASQARSQ
>Mature_439_residues
MDNQEKPTPRSPAPAPSGPRPRRRLIAFGVLAAVAIGALLWWHPWKSGGPPSAQGQPGGARQRGGPAALANLPQPVQVAT
AARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSFQEGQIVKKGDVLAQIDPRPYQISLANAQGALARDEALLATARL
DLKRYQTLVAQDSIAKQTADTQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTNGIV
VITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQIDTATGTVKLRARFENRNNLLFPN
QFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKPDNTVSVRNVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGS
AVTIPADKPKQASGARSASGASGAHGGHRRRGASQARSQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=359, Percent_Identity=48.1894150417827, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI1789929, Length=331, Percent_Identity=29.3051359516616, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789665, Length=315, Percent_Identity=34.6031746031746, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1786668, Length=379, Percent_Identity=31.1345646437995, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081796, Length=341, Percent_Identity=28.7390029325513, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081951, Length=182, Percent_Identity=30.2197802197802, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46336; Mature: 46336

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQEKPTPRSPAPAPSGPRPRRRLIAFGVLAAVAIGALLWWHPWKSGGPPSAQGQPGGA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
RQRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSFQEG
CCCCCCHHHHCCCCCCEEHHHCCCCCCEEEHHHHCCCCCCCEEEEEHHHHHHHEEECCCC
QIVKKGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLVAQDSIAKQTAD
CEEECCCEEEEECCCCEEEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTNGIV
HHHHHHHHCCCCEEEEHHHHCCCCEEEEEEEEECCCCCCCCEEEECCCCEECCCCCCCEE
VITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQIDTA
EEEECCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHCHHHHHCCCCCCC
TGTVKLRARFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKPDNT
CCEEEEEEEECCCCCEECCCHHCCCEEEEEHHCCCEECCCHHHEECCCCCEEEEECCCCE
VSVRNVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKPKQASGARSASG
EEEECCCCCCCCCCHHHHHHHHHHCCEEECCCHHHHCCCCEEEECCCCCCCCCCCCCCCC
ASGAHGGHRRRGASQARSQ
CCCCCCCHHHCCCHHHCCC
>Mature Secondary Structure
MDNQEKPTPRSPAPAPSGPRPRRRLIAFGVLAAVAIGALLWWHPWKSGGPPSAQGQPGGA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
RQRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSFQEG
CCCCCCHHHHCCCCCCEEHHHCCCCCCEEEHHHHCCCCCCCEEEEEHHHHHHHEEECCCC
QIVKKGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLVAQDSIAKQTAD
CEEECCCEEEEECCCCEEEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTNGIV
HHHHHHHHCCCCEEEEHHHHCCCCEEEEEEEEECCCCCCCCEEEECCCCEECCCCCCCEE
VITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQIDTA
EEEECCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHCHHHHHCCCCCCC
TGTVKLRARFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKPDNT
CCEEEEEEEECCCCCEECCCHHCCCEEEEEHHCCCEECCCHHHEECCCCCEEEEECCCCE
VSVRNVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKPKQASGARSASG
EEEECCCCCCCCCCHHHHHHHHHHCCEEECCCHHHHCCCCEEEECCCCCCCCCCCCCCCC
ASGAHGGHRRRGASQARSQ
CCCCCCCHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA