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The map label for this gene is yvrH [H]

Identifier: 23502854

GI number: 23502854

Start: 1928295

End: 1928978

Strand: Reverse

Name: yvrH [H]

Synonym: BR2006

Alternate gene names: 23502854

Gene position: 1928978-1928295 (Counterclockwise)

Preceding gene: 23502857

Following gene: 23502853

Centisome position: 91.52

GC content: 55.99

Gene sequence:

>684_bases
ATGACAGGCCGTACTATTCTGATTGTGGACGATGACGAAGATCTCCGTTCCATCCTCGTCGAACAGCTGGAGCTGTGCGA
AGAATTCCAGATATTGCAGGAAGACAGCGCCGGAAAAGGCATCCAGACCGCCCGCAATGGCATAGTGGACCTTCTCATCA
TGGATGTCGGCCTGCCGGATATGGACGGGCGCGAAGCGGTGAAGCTTCTGCGCAAGGGCGGCTTCAAGGCGCCAATCATC
ATGCTGACCGGCCACGACACCGAATCGGACACGATTCTCGGCCTCGAATCGGGTGCCAACGACTATGTCACCAAGCCGTT
CAAGTTCGCGGTTCTTCTGGCGCGTGTGCGCGCGCAGTTGCGCCAGCATGAGCAGAGCGAGGATGCGACCTTCATCGTGG
GGCCTTATACCTTCAAGCCCGGCCAGAAGCTTCTTATCGATGAGAAGGGCAGCAAGATCCGCCTCACCGAAAAGGAAGCG
GCGATCATCAAATATCTCTATCGCGCCGGCGACAAGGTTATCGGCCGCGATGTGCTGCTTGAGGAAGTCTGGGGTTACAA
TTCGGGTGTGACCACCCATACACTTGAAACCCACGTCTATCGCCTGCGCCAGAAAATCGAAAAAGACCCGTCAAATGCGA
CGCTTCTCGTGACAGAAAGCGGGGGATATAAGCTTGTCCCATAA

Upstream 100 bases:

>100_bases
GGCGCAAAAATTTCTTTGGCGTTTCGCCGCTTCAACTTGGCTTCATTAAATGCGATAAAACACCAAGAACGATTTAAATC
AAAGAGTAACGAGGACAGGC

Downstream 100 bases:

>100_bases
TGGACAGCGCCCGATGCAGGTGTATTGACAACTCATGGCGCTAGACGACGATATTCGCATTCTCGGCACGGTGGGCCTGT
TCGAGTCTTTCACGCCCGAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTGRTILIVDDDEDLRSILVEQLELCEEFQILQEDSAGKGIQTARNGIVDLLIMDVGLPDMDGREAVKLLRKGGFKAPII
MLTGHDTESDTILGLESGANDYVTKPFKFAVLLARVRAQLRQHEQSEDATFIVGPYTFKPGQKLLIDEKGSKIRLTEKEA
AIIKYLYRAGDKVIGRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIEKDPSNATLLVTESGGYKLVP

Sequences:

>Translated_227_residues
MTGRTILIVDDDEDLRSILVEQLELCEEFQILQEDSAGKGIQTARNGIVDLLIMDVGLPDMDGREAVKLLRKGGFKAPII
MLTGHDTESDTILGLESGANDYVTKPFKFAVLLARVRAQLRQHEQSEDATFIVGPYTFKPGQKLLIDEKGSKIRLTEKEA
AIIKYLYRAGDKVIGRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIEKDPSNATLLVTESGGYKLVP
>Mature_226_residues
TGRTILIVDDDEDLRSILVEQLELCEEFQILQEDSAGKGIQTARNGIVDLLIMDVGLPDMDGREAVKLLRKGGFKAPIIM
LTGHDTESDTILGLESGANDYVTKPFKFAVLLARVRAQLRQHEQSEDATFIVGPYTFKPGQKLLIDEKGSKIRLTEKEAA
IIKYLYRAGDKVIGRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIEKDPSNATLLVTESGGYKLVP

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=33.4821428571429, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=32.8888888888889, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=33.1877729257642, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=32.1739130434783, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789402, Length=160, Percent_Identity=31.25, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=30.1310043668122, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=26.8722466960352, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=28.310502283105, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=33.7662337662338, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=28.1938325991189, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=27.3913043478261, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=29.5652173913043, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=28.8702928870293, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=253, Percent_Identity=24.5059288537549, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25331; Mature: 25200

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRTILIVDDDEDLRSILVEQLELCEEFQILQEDSAGKGIQTARNGIVDLLIMDVGLPD
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEEECCCCC
MDGREAVKLLRKGGFKAPIIMLTGHDTESDTILGLESGANDYVTKPFKFAVLLARVRAQL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
RQHEQSEDATFIVGPYTFKPGQKLLIDEKGSKIRLTEKEAAIIKYLYRAGDKVIGRDVLL
HHCCCCCCCEEEEECEEECCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHH
EEVWGYNSGVTTHTLETHVYRLRQKIEKDPSNATLLVTESGGYKLVP
HHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
TGRTILIVDDDEDLRSILVEQLELCEEFQILQEDSAGKGIQTARNGIVDLLIMDVGLPD
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEEECCCCC
MDGREAVKLLRKGGFKAPIIMLTGHDTESDTILGLESGANDYVTKPFKFAVLLARVRAQL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
RQHEQSEDATFIVGPYTFKPGQKLLIDEKGSKIRLTEKEAAIIKYLYRAGDKVIGRDVLL
HHCCCCCCCEEEEECEEECCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHH
EEVWGYNSGVTTHTLETHVYRLRQKIEKDPSNATLLVTESGGYKLVP
HHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]